research Melan-A Positive cells significantly expressed in immune-targeted follicles of Alopecia Areata
Melanocytes may trigger the immune response in alopecia areata, affecting hair regrowth.
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research 1380 Ganoderma lucidum extract attenuates Corticotropin-Releasing Factor (CRF)-induced cellular senescence in human hair follicular cells
Ganoderma lucidum extract can potentially reduce stress-induced hair loss by slowing down premature hair aging and removing harmful substances.
research Supplementary Material for: Life of the B10 mouse: a view from the hair follicles and tissue stem cells
Mouse skin and hair aging starts at 200 days, with changes in hair follicles and more white hairs as signs of aging.
research Changes in Characteristics of Murine Hair Follicles and Tissue Stem Cells Throughout Life
Mouse hair follicles age, causing more white hairs due to fewer pigment stem cells.
research 244 Defective maintenance of hair follicle stem cells through COL17A1 loss orchestrates the hair follicle aging program
Loss of COL17A1 causes hair follicle stem cells to age and leads to hair loss.
research Generation of iPS-derived model cells for the analysis of hair development
Researchers created a cell model to study hair growth and test hair-growth drugs.
research The variable cell
Hairless protein is key for hair growth, cell differences cause gene expression variation, and the N-end rule pathway senses nitric oxide for protein breakdown.
research N02. Hair and Nails
Researchers found new hair and nail genes, how hair reacts to UV, differences in white and pigmented hair growth, nerve changes in alopecia, treatments for baldness and alopecia, a toenail condition linked to a genetic disorder, and that nail fungus is more common in people with psoriasis.
research Hair morphogenesisin vitro: formation of hair structures suitable for implantation
Scientists created early-stage hairs from mouse cells that grew into normal, pigmented hair when implanted into other mice.
research Recreation of a hair follicle regenerative microenvironment: Successes and pitfalls
Hair growth environment recreated with challenges; stem cells make successful skin organoids.
research Changes in the Expression of Smooth Muscle Cell–Related Genes in Human Dermal Sheath Cup Cells Associated with the Treatment Outcome of Autologous Cell–Based Therapy for Male and Female Pattern Hair Loss
Lower levels of certain genes in hair cells improve hair loss treatment outcomes.
research Regenerative Medicine Approaches for Engineering a Human Hair Follicle
New treatments for hair loss show promise, including plasma, stem cells, and hair-stimulating complexes, but more research is needed to fully understand them.
research Clonal Growth of Dermal Papilla Cells in Hydrogels Reveals Intrinsic Differences between Sox2-Positive and -Negative Cells In Vitro and In Vivo
Sox2-positive dermal papilla cells have unique characteristics and contribute more to skin and hair follicle formation than Sox2-negative cells.
research Functional hair follicle regeneration: an updated review
Hair follicle regeneration possible, more research needed.
research Hair follicle stem cells as a skin‐organizing signaling center during adult homeostasis
Hair follicle stem cells help maintain skin health and could improve skin replacement therapies.
research Engineering the future of hair follicle regeneration and delivery
Hair follicle regeneration and delivery is complex due to many molecular and cellular factors.
research Detecting the Mechanism behind the Transition from Fixed Two-Dimensional Patterned Sika Deer (Cervus nippon) Dermal Papilla Cells to Three-Dimensional Pattern
The study concluded that changing the culture conditions can cause sika deer skin cells to switch from a flat to a 3D pattern, which is important for creating hair follicles.
research Sox2-positive dermal papilla cells specify hair follicle type in mammalian epidermis
Sox2-positive cells determine specific hair follicle types in mammals.
research Stem Cells in Skin Regeneration, Wound Healing, and Their Clinical Applications
Stem cells are crucial for skin repair and new treatments for chronic wounds.
research Regenerating the skin: a task for the heterogeneous stem cell pool and surrounding niche
Different types of stem cells and their environments are key to skin repair and maintenance.
research Epidermal Development in Mammals: Key Regulators, Signals from Beneath, and Stem Cells
Skin development in mammals is controlled by key proteins and signals from underlying cells, involving stem cells for maintenance and repair.
research Sustained release of dermal papilla-derived extracellular vesicles from injectable microgel promotes hair growth
Injecting a special gel with human protein particles can help hair grow.
research Differences in Expression of Specific Biomarkers Distinguish Human Beard from Scalp Dermal Papilla Cells
Beard and scalp hair cells have different gene expressions, which may affect beard growth characteristics.
research Neural progenitor cell-derived nanovesicles promote hair follicle growth via miR-100
Tiny particles from brain cells help hair grow by targeting a specific hair growth pathway.
research Engineering the niche for hair regeneration — A critical review
Further research is needed to improve hair regeneration using stem cells and nanomaterials.
research Costunolide promotes the proliferation of human hair follicle dermal papilla cells and induces hair growth in C57BL/6 mice
Costunolide helps human hair cells grow and can stimulate hair growth in mice.
research The effect of cilostazol, a phosphodiesterase 3 (PDE3) inhibitor, on human hair growth with the dual promoting mechanisms
Cilostazol helps hair grow by making hair root cells grow faster and changing growth factor levels.
research Establishment and characterization of five immortalized human scalp dermal papilla cell lines
Researchers created five new human scalp cell lines that could be useful for hair growth and loss research.
research Future Horizons in Hair Restoration
New cell-based therapies may improve hair loss treatments in the future.
research Integral Roles of Specific Proteoglycans in Hair Growth and Hair Loss: Mechanisms behind the Bioactivity of Proteoglycan Replacement Therapy with Nourkrin® with Marilex® in Pattern Hair Loss and Telogen Effluvium
Proteoglycans are important for hair growth, and a specific treatment can help reduce hair loss.