20 citations
,
February 2012 in “Archives of dermatology” Leg hair transplants can create a natural-looking hairline and show successful growth over several years.
23 citations
,
October 2021 in “Cell Stem Cell” Hair thinning causes stem cell loss through a process involving Piezo1, calcium, and TNF-α.
November 2014 in “British Journal of Dermatology” Hair loss is due to thinner hairs, not less hairs; hair diameter indicates balding progression and treatment effectiveness.
1 citations
,
January 2010 in “International Journal of Trichology” Hair loss affects quality of life, and options like wigs and scalp treatments can help when medical solutions aren't enough.
January 2018 in “bioRxiv (Cold Spring Harbor Laboratory)” The mutant HR bmh protein mis-localizes in cells, affecting skin and hair development.
73 citations
,
May 2009 in “Proceedings of the National Academy of Sciences” Disrupting the Sox21 gene in mice causes hair loss and regrowth cycles.
9 citations
,
April 1985 in “Archives of Dermatology” Recognizing the "bamboo hair defect" is crucial for diagnosing Netherton's syndrome.
3 citations
,
January 2021 in “Plastic and Aesthetic Research” Hair loss reduces hair thickness and coverage, but drug treatments mainly revive dormant hairs rather than reverse thinning; patients often undervalue their hair loss severity.
16 citations
,
January 1998 in “Dermatology” Androgens may worsen a natural hair resting phase, possibly leading to hair loss.
16 citations
,
April 2021 in “Frontiers in Cell and Developmental Biology” New hair follicles could be created to treat hair loss.
June 2013 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” Wnt ligand secretion by hair follicle cells is essential for hair growth and repair.
43 citations
,
November 1975 in “Archives of Dermatology” Testosterone affects hair loss, acne, and excessive hair growth, and antiandrogens can help treat these conditions.
July 2002 in “Journal of applied cosmetology” Hair growth issues can be linked to genetics, diseases, or medications, and new treatments are being developed.
3 citations
,
January 2021 in “Veterinary dermatology” A litter of cats had a hair condition similar to a mouse mutation, leading to hair loss and abnormal hair and skin.
2 citations
,
July 1998 in “International Journal of Dermatology” We need a safe, reliable way to stop severe hair loss.
5 citations
,
March 2001 in “Journal of biomechanics” Growing hairs are easier to pull out than resting hairs due to different anchorage strengths.
January 2006 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” 24 citations
,
May 2000 in “Journal of the American Academy of Dermatology” Pseudopelade can affect both the scalp and beard, causing hair loss.
The document concludes that Androgenic Alopecia is a type of hair loss, commonly known as baldness.
2 citations
,
September 2022 in “Organoid” A new method was developed to efficiently grow skin hair follicles from stem cells, potentially aiding alopecia treatment.
1 citations
,
July 2005 in “Informa Healthcare eBooks” Hair follicles could be used for targeted drug delivery, with liposomal systems showing promise for this method.
December 2014 in “PubMed” A scalp biopsy can help confirm hair loss types when other methods don't provide a clear diagnosis.
February 2020 in “Our Dermatology Online” A synthetic drug and a South American herb may help treat alopecia areata in Chinese men.
148 citations
,
September 2003 in “Journal of Investigative Dermatology Symposium Proceedings” Alopecia areata is an autoimmune disorder causing hair loss, linked to specific hair follicle antigens and genetic factors.
May 2009 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” PPARgamma is crucial for healthy hair follicles, and its loss causes scarring alopecia.
37 citations
,
January 2010 in “Journal of Clinical Investigation” N-WASP is essential for normal hair growth in mice.
3 citations
,
November 2015 in “Journal of Investigative Dermatology” Testosterone can both promote hair growth and cause baldness by affecting hair growth signals.
June 2013 in “Digital Repository (National Repository of Grey Literature)” Hair loss negatively affects self-esteem and social interactions, but people use coping strategies like wigs or shaving to manage it.
1 citations
,
August 1994 in “Journal of Cutaneous Pathology” Hair loss happens due to faster cell growth and fewer cells in affected follicles.
2 citations
,
January 2019 in “Case Reports in Dermatology” A 66-year-old woman's thick scalp and hair loss were confirmed as lipedematous alopecia, a rare condition possibly influenced by genetics, with no effective treatment known.