6 citations
,
June 2018 in “Journal of Stomatology, Oral and Maxillofacial Surgery” Nanofat grafting is better for delicate areas and combining it with lipofilling might improve hair loss treatment.
New therapies like JAK inhibitors, PRP, and stem cell treatments show promise for better alopecia management.
277 citations
,
July 2011 in “Journal of the Dermatology Nurses’ Association” The skin's layers protect, sense, and regulate the body's internal balance, but can be prone to cancer.
156 citations
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October 2012 in “Seminars in Cell & Developmental Biology” Different types of stem cells in hair follicles play unique roles in wound healing and hair growth, with some stem cells not originating from existing hair follicles but from non-hair follicle cells. WNT signaling and the Lhx2 factor are key in creating new hair follicles.
153 citations
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October 2007 in “Cell Stem Cell” New research suggests that skin cell renewal may not require a special type of cell previously thought to be essential.
58 citations
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November 2013 in “Journal of Innovative Optical Health Sciences” Multiphoton microscopy is a promising tool for detailed skin imaging and could improve patient care if its challenges are addressed.
43 citations
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January 2012 in “Biological Research” The origins of many adult skin stem cells are still mostly unknown.
34 citations
,
April 2018 in “EMBO journal” The protein SLC1A3 is important for activating skin stem cells and is necessary for normal hair and skin growth in mice.
16 citations
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September 2016 in “Experimental Dermatology” Two-photon microscopy effectively tracks live stem cell activity in mouse skin with minimal harm and clear images.
6 citations
,
January 2009 in “Elsevier eBooks” The skin has multiple layers and cells, serves as a protective barrier, helps regulate temperature, enables sensation, affects appearance, and is involved in vitamin D synthesis.
5 citations
,
January 2019 in “Elsevier eBooks” Current therapies cannot fully regenerate adult skin without scars; more research is needed for scar-free healing.
1 citations
,
October 2025 in “International Journal of Nanomedicine” Exosomes could revolutionize skin disease treatment and healing.
1 citations
,
January 2023 in “Burns and trauma” Tiny particles from 3D-grown skin cells speed up wound healing by promoting blood vessel growth.
95 citations
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November 2016 in “Journal of The American Academy of Dermatology” Treatments for permanent hair loss from scarring aim to stop further loss, not regrow hair, and vary by condition, with partial success common.
20 citations
,
July 2013 in “European Journal of Oral Sciences” A new PAX9 gene mutation causes missing teeth and hair problems, but not skin or nail issues.
14 citations
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June 2013 in “Anais Brasileiros de Dermatologia” Follicular red dots may be a normal feature seen in people with less skin pigmentation, not necessarily indicating a scalp disorder.
8 citations
,
March 2021 in “Medicina-lithuania” PRP treatment may promote hair growth and improve hair density in women with AGA, but more research is needed.
3 citations
,
February 2021 in “Medical journal, Armed Forces India” Combination therapy promotes better hair growth and density.
Photobiomodulation improves the quality of life for people with hair loss.
Low-Level Light Therapy improves quality of life more for women than men with hair loss.
May 2017 in “InTech eBooks” Trichoscopy and trichogram are useful for diagnosing hair and scalp conditions.
23 citations
,
June 2018 in “Facial Plastic Surgery” Platelet-Rich Plasma (PRP) is a low-risk treatment for Androgenic Alopecia (AGA) that generally improves hair count or density, but more research is needed for optimization.
1 citations
,
October 2013 in “Expert Review of Dermatology” Diagnosing alopecia areata is challenging and requires careful examination and various tests to distinguish it from other hair loss types.
The treatment showed limited success in repigmenting hair for vitiligo-associated leukotrichia.
February 2026 in “Frontiers in Medicine” Oral minoxidil improved hair loss more than oral dutasteride.
January 2026 in “International Journal of All Research Education & Scientific Methods” Alopecia is caused by various factors, and new treatments like gene editing and regenerative medicine offer hope for personalized hair regrowth solutions.
August 2025 in “Benha Medical Journal” PRP therapy improves hair growth safely in androgenetic alopecia but needs standardized methods.
1160 citations
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November 2018 in “Physiological Reviews” The document concludes that better targeted treatments are needed for wound healing, and single-cell technologies may improve cell-based therapies.
688 citations
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June 2007 in “Cell Stem Cell” Removing the ATR gene in adult mice causes rapid aging and stem cell loss.
305 citations
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February 2007 in “Hormone and metabolic research” Human skin makes sexual hormones that affect hair growth, skin health, and healing; too much can cause acne and hair loss, while treatments can manage these conditions.