research Structural & functional studies of L-PGDS and SMPDL3A enzymes in lipid signaling family
L-PGDS has specific binding sites for its functions and could help in drug delivery system design.
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research Long-term treatment within a maximum of 96 weeks of tinea unguium with long-pulsed neodymium-doped yttrium aluminum garnet laser
Laser treatment is safe and can effectively treat toenail fungus, especially when combined with other treatments if no improvement is seen after about a year.
research Povidone-iodine nail solution is active in treating chemotherapy-associated paronychia
Povidone-iodine nail solution effectively treats nail infections caused by chemotherapy.
research Diagnosis and Treatment of Polycystic Ovary Syndrome: An Endocrine Society Clinical Practice Guideline
The guideline suggests using specific criteria to diagnose PCOS, recommends various treatments for its symptoms, and advises screening for related health issues.
research Negative Impact of Testosterone Deficiency and 5α-Reductase Inhibitors Therapy on Metabolic and Sexual Function in Men
Low testosterone and 5α-reductase inhibitors can harm men's metabolic and sexual health; testosterone therapy may help, but discussing 5α-RIs' side effects is important.
research Estimation of biological heart age using cardiovascular magnetic resonance radiomics
Obesity and lifestyle strongly affect heart aging.
research The intragenic mRNA-microRNA regulatory network during telogen-anagen hair follicle transition in the cashmere goat
The research found that a complex gene network, controlled by microRNAs, is important for hair growth in cashmere goats.
research Male-pattern baldness and incident coronary heart disease and risk factors in the Heinz Nixdorf Recall Study
Male-pattern baldness is weakly linked to some heart disease risk factors but not a strong indicator for heart disease.
research Interventional studies for polycystic ovarian syndrome in children and adolescents
Early treatment and lifestyle changes are important for managing PCOS in young people to prevent long-term health issues.
research Health is Wealth & Wealth is Pugos Nutrition
Good nutrition is crucial for health and preventing disease, and supplements can help prevent nutrient deficiencies.
research Insulin Resistance and Polycystic Ovary Syndrome
Insulin resistance is linked to PCOS and can lead to other health issues, but treatments like metformin can help manage symptoms.
research A Comprehensive Review on Metabolic Syndrome
Managing metabolic syndrome needs both lifestyle changes and medical treatments.
research A comprehensive review of the medical complications associated with restrictive eating behaviors in anorexia nervosa
Anorexia nervosa causes serious health issues, best treated with a team approach focusing on nutrition.
research The skin and obesity
Obesity worsens skin health and losing weight can improve skin conditions.
research Targeting the pre-receptor metabolism of cortisol as a novel therapy in obesity and diabetes
Blocking a specific enzyme might help treat obesity and diabetes, but more research is needed to ensure it's safe.
research Insulin resistance and the long-term consequences of polycystic ovary syndrome
Insulin resistance in women with PCOS can lead to serious health issues, but lifestyle changes and certain medications can help manage symptoms.
research Androgenetic Alopecia: Relationship to Anthropometric Indices, Blood Pressure and Life-Style Habits
Men with hair loss have higher BMI, waist size, blood pressure, and are linked to smoking and inactivity.
research Feasibility of implementing current best clinical practice for people who are using anabolic androgenic steroids within a Swiss primary care practice: a quality assurance study
Integrating best practices for steroid users in Swiss primary care is feasible and beneficial, but doping laws need change.
research Pharmacodynamic Evaluation: Endocrinology
The conclusion is that endocrinology significantly impacts medicine with various common medications used for treatment.
research Genetic, hormonal and metabolic aspects of PCOS: an update
The document concludes that insulin resistance is key in PCOS development and early treatment is crucial to prevent complications.
research Androgen Therapy in Women: A Reappraisal: An Endocrine Society Clinical Practice Guideline
The guidelines advise against using testosterone and DHEA in women for most conditions due to safety and effectiveness concerns, but suggest considering testosterone for postmenopausal women with low sexual desire.
research JAK-inhibitors. New players in the field of immune-mediated diseases, beyond rheumatoid arthritis
JAK inhibitors are effective in treating various immune-related diseases, not just rheumatoid arthritis.
research Testosterone, Dihydrotestosterone, and Incident Cardiovascular Disease and Mortality in the Cardiovascular Health Study
DHT may increase the risk of heart disease and death in elderly men.
research Peroxisome proliferator-activated receptors (PPARs) and PPAR agonists: the ‘future’ in dermatology therapeutics?
PPAR agonists show promise for skin conditions but need more research before being a main treatment.
research Androgenetic alopecia and insulin resistance in young men
Hair loss in young men linked to higher risk of insulin resistance and metabolic issues.
research Prevalence of Hyperandrogenic States in Late Adolescent and Young Women: Epidemiological Survey on Italian High-School Students
Many young Italian women have hyperandrogenic disorders like PCOS, which are linked to age, body weight, and insulin resistance.
research Gender-Affirming Hormone Therapy for Transgender Men
Testosterone therapy seems safe and effective for transgender men with proper care, but more long-term research is needed.
research Effect of finasteride in idiopathic hirsutism
Finasteride significantly reduces hair growth in women with idiopathic hirsutism.
research Adverse health effects of androgen use
Using anabolic androgenic steroids can cause serious, lasting health problems in many parts of the body.
research Anti-androgens for the treatment of hirsutism
Different anti-androgen medications can help treat excessive hair growth, but the right choice depends on accurate diagnosis.