research The role of P-cadherin in skin biology and skin pathology: lessons from the hair follicle
P-cadherin is important for hair growth and health, and its problems can cause hair and skin disorders.
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research Stem cell apoptosis in HIV‐1 alopecia
HIV-1 may cause increased stem cell death in hair follicles, leading to hair loss.
research Targets to treat androgen excess in polycystic ovary syndrome
The conclusion is that while oral contraceptive pills are effective for PCOS-related high androgen levels, new treatments with fewer side effects are needed.
research Comparative Proteomic Analysis in Scar-Free Skin Regeneration in Acomys cahirinus and Scarring Mus musculus
The African spiny mouse heals skin without scarring due to different protein activity compared to the common house mouse, which heals with scarring.
research Identifying molecular targets for reverse aging using integrated network analysis of transcriptomic and epigenomic changes during aging
Curcumin may help reverse aging by targeting specific genes.
research The direct inhibitory effect of dutasteride or finasteride on androgen receptor activity is cell line specific
Dutasteride and finasteride affect different cell types differently.
research Clinical review 74: Dermatological manifestations of endocrine disorders.
Skin changes can indicate hormonal imbalances and help diagnose endocrine disorders.
research Proteomic analysis of balding and non-balding mesenchyme-derived dermal papilla cells from androgenetic alopecia patients using on-line two-dimensional reversed phase-reversed phase LC–MS/MS
Found different proteins in balding and non-balding cells, giving insight into hair loss causes.
research Lineage Tracing of Hair Follicle Stem Cells in Epidermal Whole Mounts
The method allows for 3D tracking of hair follicle stem cells and shows they can regenerate hair for up to 180 days.
research Influence of Dosing Time on the Efficacy and Safety of Finasteride in Rats
Dosing time affects finasteride's effectiveness and safety in rats.
research Non-rhizobial nodule endophytes improve nodulation, change root exudation pattern and promote the growth of lentil, for prospective application in fallow soil
Certain bacteria can boost lentil growth and improve soil used for farming.
research Single-cell transcriptomics defines keratinocyte differentiation in avian scutate scales
The research identified two types of keratinocytes in chicken scales: one for hard scales and another for soft skin, with similarities to human skin differentiation.
research Testicular Steroidogenesis
Genetic defects in testosterone production can cause hormonal and developmental disorders, and more research is needed to understand androgen regulation and develop safer treatments.
research Mechanism of androgenic alopecia: Addressing speculations through empirical evidences
Hair loss in men is mainly caused by hormones and genes, and while current treatments can slow it down, they can't fully stop it.
research The Role of Topical Vitamin D in Vitiligo: A Narrative Literature Review
Topical vitamin D is effective in treating vitiligo with few side effects.
research Production of a 135-residue long N-truncated human keratinocyte growth factor 1 in Escherichia coli
KGF-1 135 is a stable and effective alternative for treating oral mucositis.
research Understanding the molecular basis of mesenchymal stem cell stemness: implications for clinical applications
Understanding how mesenchymal stem cells stay undifferentiated can improve their use in treating diseases.
research Melanocytes and Vitiligo (and Hair Graying)
Melanocytes produce melanin; their defects cause vitiligo and hair graying, with treatments available for vitiligo.
research Deciphering the cellular landscape and genetic underpinnings of fiber diameter determined by dermal papilla cells in fine-wool sheep
Dermal papilla cells are key to fine wool growth in sheep.
research SARS-CoV-2 infection reduces the number of spermatogonial stem cells and dysregulates the transcriptional landscape of the human testis
COVID-19 can harm male fertility by reducing sperm stem cells and damaging testicular function.
research Hair cell loss – cause or consequence of hearing loss?
Hair cell loss usually happens after hearing loss starts.
research Exosomes in Skin Rejuvenation: Systematic Review of Anti-Aging Effects and Clinical Applications
Exosomes can improve skin elasticity, reduce wrinkles, and enhance hydration, but more research is needed.
research The emerging role of exosomes in skin health and dermatological conditions
Exosomes can improve skin treatments with fewer side effects.
research Medical Physics and Laser Technology: Advancements and Applications in Modern Healthcare
Advancements in medical physics and laser technology are improving healthcare but access remains unequal globally.
research Causal associations between plasma proteins and prostate cancer: a Proteome-Wide Mendelian Randomization
Certain plasma proteins are linked to prostate cancer risk and could help in early detection and treatment.
research Unlocking the Medicinal Potential of Plant-Derived Extracellular Vesicles: current Progress and Future Perspectives
Plant-derived extracellular vesicles show promise for treating diseases like cancer and inflammation.
research Regenerative potential and clinical application of mesenchymal stem cell-derived exosomes (review)
MSC-derived exosomes can help treat COVID-19, hair loss, skin aging, and arthritis.
research Avaliação do impacto da redução significativa de peso pela dieta cetogênica de muito baixa caloria nos parâmetros metabólicos, inflamatórios, hormonais e seminais de homens obesos
A very low-calorie ketogenic diet led to weight loss and improved metabolic and hormonal health in obese men, with better sperm motility.
research NATURAL ANTIVIRALS FOR THE MANAGEMENT OF SARS-COVID-19: A REVIEW
Natural plant compounds may offer safer COVID-19 treatments with fewer side effects.
research Proteins observed in scalp hair from preschool children
Mothers have more hair proteins than their children, with age-related differences in protein patterns, and some proteins in hair could indicate early childhood development.