February 2017 in “International Journal on Advanced Science, Engineering and Information Technology” Human hair follicle stem cells can grow and turn into skin cells on chitosan templates, which may help in regenerative medicine.
45 citations
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May 2018 in “Stem Cell Research & Therapy” Using patients' own fat-derived cells to treat alopecia areata significantly improved hair growth and was safe.
295 citations
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June 2009 in “Science” Stromal stem cells may help heal wounds by becoming structural cells or affecting the immune system, but more research is needed to understand how.
November 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” Disrupted cholesterol production impairs hair follicle stem cells, leading to hair loss.
7 citations
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March 2012 in “European Journal of Pediatrics” A boy with a rare skin condition and kidney disease improved with cyclosporine after steroids failed, suggesting a new treatment approach.
August 2016 in “The journal of investigative dermatology/Journal of investigative dermatology” The hexosamine pathway helps protect skin cells from stress and may improve skin and hair health.
51 citations
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April 2013 in “Journal of Investigative Dermatology” Hair follicle stem cells rely on nearby blood vessels for their maintenance and function.
3 citations
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January 2021 in “Oxidative Medicine and Cellular Longevity” Nrf-2-modified stem cells from hair follicles significantly improve ulcerative colitis in rats.
April 2026 in “Research Square”
99 citations
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January 2014 in “Nature communications” Scientists created stem cells that can grow hair and skin.
January 2021 in “Pediatric Oncall” Autoimmune hepatitis in children often affects girls and can be treated successfully with medication.
4 citations
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January 2025 in “The Journal of Cell Biology” Ceramide Synthase 4 is crucial for maintaining hair follicle stem cells and preventing hair loss.
13 citations
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September 2017 in “Cytometry Part A” Horse hair follicles could be a new source of stem cells for healing horses.
13 citations
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January 1997 in “Biochemical Pharmacology” Human liver enzyme DHEA ST helps process minoxidil.
66 citations
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December 2013 in “Nature Cell Biology” Inactive hair follicle stem cells help prevent skin cancer.
5 citations
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June 2015 in “British Journal of Dermatology” A certain medication improved severe itching in a boy with liver and bowel disease by reducing histamine levels, suggesting a new treatment target.
November 2022 in “Journal of Investigative Dermatology” NCSTN gene mutation causes abnormal skin cell differentiation and more inflammation, contributing to Hidradenitis Suppurativa.
Bipotent dermal stem cells and specific macrophages are crucial for hair regrowth and regeneration.
153 citations
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October 2007 in “Cell Stem Cell” New research suggests that skin cell renewal may not require a special type of cell previously thought to be essential.
November 2013 in “Elsevier eBooks” Skin and hair renewal is maintained by both fast and slow cycling stem cells, with hair regrowth primarily driven by specific stem cells in the hair follicle bulge. These cells can also help heal wounds and potentially treat hair loss.
1 citations
,
May 2026 in “Nature Communications” CD19-CAR T cell therapy may help regenerate skin in systemic sclerosis.
508 citations
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February 2007 in “Cell” Epithelial stem cells are crucial for tissue renewal and repair, and understanding them could improve treatments for damage and cancer.
23 citations
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November 2018 in “Development, Growth & Differentiation” Epidermal stem cells have various roles in skin beyond just maintenance, including forming specialized structures and aiding in skin repair and regeneration.
March 2023 in “Scientific reports” Hair growth-related cells need the enzyme SCD1 to help maintain the area that supports hair growth.
51 citations
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February 2004 in “Journal of Investigative Dermatology” MCSP may help identify and regulate skin stem cells, affecting hair growth and regeneration.
11 citations
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December 2017 in “Orphanet Journal of Rare Diseases” A new mutation in the ST14 gene broadens the understanding of ichthyosis-hypotrichosis syndrome.
7 citations
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March 2017 in “Experimental and Therapeutic Medicine” Hair follicle cells can help keep embryonic stem cells undifferentiated.
Hair follicle-derived sheets can effectively treat vitiligo by repigmenting skin.
2 citations
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January 2016 Rat hair follicle stem cells can be successfully cultured and may be useful for creating tissue-engineered hair, vessels, and skin.
89 citations
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May 2005 in “Stem Cells” Mouse skin has special cells in the epidermis that decrease with age and are linked to keratinocyte stem cells.