14 citations
,
May 2013 in “American Journal of Physiology-endocrinology and Metabolism” Removing myelin protein zero-like 3 in mice leads to better metabolism and resistance to obesity.
11 citations
,
January 2017 in “Journal of Endocrinology/Journal of endocrinology” Female mice with disrupted 5α-reductase 1 had significant metabolic issues, including stress response problems, insulin resistance, liver fat buildup, and obesity.
5 citations
,
February 2025 in “International Journal of Molecular Sciences” Vitisin A reduces triglycerides better than Cyanidin-3-O-glucoside.
July 2022 in “World Journal of Advanced Research and Reviews” Piptadeniastrum africanum and Cordia plathytyrsa can increase testosterone without major metabolic changes, but may affect triglycerides and creatinine.
90 citations
,
February 2013 in “The Journal of Clinical Endocrinology and Metabolism” Women with PCOS have more body fat and thicker fat layers in certain abdominal areas than women without PCOS.
June 2024 in “Current Developments in Nutrition” KeraGLO improves skin and hair health.
165 citations
,
February 2014 in “Phytotherapy Research” Myrtle has various health benefits and potential for medicine development.
26 citations
,
April 2007 in “Journal of pediatric gastroenterology and nutrition” A teenage girl with high androgen levels and PCOS developed a rare liver tumor, suggesting a possible link between high androgens and the tumor's growth.
Higher apelin-12 levels may indicate more severe acne.
7 citations
,
March 2011 in “Hormone and Metabolic Research” Certain gene variations might help protect against insulin resistance and glucose intolerance in people with Polycystic Ovary Syndrome.
August 2023 in “Gadua Journal of Pure and Allied Science” Ziziphus spina-christi leaf extract lowered blood sugar and protected organs in diabetic rats.
33 citations
,
September 2014 in “Reproductive Biology and Endocrinology” High afamin levels are linked to metabolic syndrome and may predict its development in women with insulin resistance.
7 citations
,
August 2019 in “Journal of Ovarian Research” Blood removal and birth control pills both helped with hormone levels in women with PCOS, but birth control was better for regular periods and blood removal had fewer side effects.
1 citations
,
March 2020 in “Functional foods in health and disease/Journal of functional foods in health & disease” OM-X® helped prevent negative effects of Vitamin C deficiency in mice, suggesting it could protect organs and regulate metabolism.
343 citations
,
December 2008 in “Endocrine Reviews” Metformin helps with menstrual cycles and insulin levels in PCOS but is less effective for hair growth, diabetes prevention, and weight loss, and may improve fertility and reduce diabetes risk.
4 citations
,
February 2011 in “Nature Reviews Endocrinology” Metformin and thiazolidinediones are similarly effective for PCOS, but metformin is often preferred due to fewer side effects.
3 citations
,
August 2017 in “International journal of reproduction, contraception, obstetrics and gynecology” People with PCOS have higher levels of PAI-1, which may increase their risk of heart disease and fertility issues.
6 citations
,
January 2019 in “F1000Research” High triglyceride levels are a key factor affecting testosterone levels in women with PCOS.
119 citations
,
November 2009 in “Human Reproduction” Women with PCOS and higher androgen levels are more likely to have fatty liver disease.
114 citations
,
January 2014 in “World Journal of Gastroenterology” People with PCOS, especially if obese, often have NAFLD, linked to obesity, insulin resistance, and high androgen levels.
45 citations
,
January 2013 in “Journal of Human Reproductive Sciences” Women with PCOS are more likely to have fatty liver disease, especially if they have metabolic problems.
December 2025 in “Scientific Reports” Cedrol may help reduce liver fat and fat cell growth caused by corticosteroids.
December 2023 in “Pakistan Journal of Medical & Health Sciences” NAFLD in PCOS patients is linked to early kidney problems.
3 citations
,
June 2024 in “Journal of Neuroendocrinology” Many women with PCOS have abnormal cholesterol levels, needing careful management.
4 citations
,
January 2018 in “JBRA assisted reproduction” Orlistat helped reduce weight and testosterone in obese women with PCOS but did not significantly affect other androgens or cholesterol levels.
January 2021 in “Menoufia Medical Journal” People with early-onset androgenetic alopecia may have a higher risk of heart disease due to abnormal blood lipid levels.
June 2021 in “Egyptian Journal of Dermatology and Venereology” Psoriasis, acne, and hair loss are linked to unhealthy cholesterol levels, increasing heart disease risk.
1 citations
,
February 2013 in “African Journal of Pharmacy and Pharmacology” Finasteride lowers good cholesterol, raises bad fats, and may increase heart disease risk.
1 citations
,
April 2021 in “Deneysel ve klinik tıp dergisi/Journal of experimental and clinical medicine” Women with PCOS have a higher risk of metabolic syndrome and need lifestyle changes and treatment.
1 citations
,
June 2017 in “International journal of reproduction, contraception, obstetrics and gynecology” N-acetylcysteine was more effective and had fewer side effects than metformin for improving insulin resistance in women with PCOS.