59 citations
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September 2007 in “Biochemical and Biophysical Research Communications” The TRPV3 gene mutation affects hair growth by keeping mice in the growth phase longer, which could help treat hair loss.
56 citations
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September 2013 in “Journal of Biochemistry and Molecular Biology” Androgens increase a growth factor in hair cells by creating reactive oxygen species, and antioxidants might help treat hair loss.
55 citations
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January 2002 in “Journal of liposome research” New liposomal formulations may improve delivery of treatments to hair follicles, potentially helping with hair loss.
52 citations
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January 2020 in “Scientific Reports” NLCs with manual massage greatly improve clobetasol delivery to hair follicles.
49 citations
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October 2017 in “Nutrients” Equisetum debile extract, especially the ethyl acetate type, may be a promising natural ingredient for anti-hair loss products.
48 citations
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February 2016 in “Scientific Reports” Researchers created rat liver stem cells that could help repair liver failure in rats and may be useful for studying human liver diseases.
47 citations
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October 2016 in “Molecular and Cellular Endocrinology” Androgens prevent hair growth by changing Wnt signals in cells.
47 citations
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October 1989 in “Circulation Research” The study explains how minoxidil sulfate causes vasodilation in rabbits by opening potassium channels and inhibiting calcium channels.
45 citations
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August 2011 in “Journal of Microencapsulation” Chitosan microparticles improve minoxidil sulphate delivery, potentially reducing daily applications.
42 citations
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February 2017 in “Scientific Reports” Researchers found a way to create cells from stem cells that act like human cells important for hair growth and could be used for hair regeneration treatments.
41 citations
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September 2010 in “Journal of dermatological science” Bone marrow and umbilical cord stem cells can help grow new hair.
40 citations
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November 2021 in “npj Regenerative Medicine” Adult spiny mice recover better from heart attacks than common lab mice.
40 citations
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March 2019 in “Nature Communications” CRAC channels are crucial for the development and function of specialized immune cells, preventing severe inflammation and autoimmune diseases.
40 citations
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July 2015 in “Journal of Cellular Biochemistry” Cysteine helps maintain keratin production in skin cells even when iron is low.
40 citations
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December 2012 in “PLoS ONE” Removing Ctip2 in skin cells causes skin inflammation similar to atopic dermatitis.
39 citations
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January 2015 in “International journal for parasitology/International Journal for Parasitology” Epidermal keratinocytes start wound healing and inflammation after schistosome infection.
37 citations
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April 2011 in “Journal of Biological Chemistry” LEF1 interacts with Vitamin D Receptor, affecting hair follicle regeneration and this could be linked to hair loss conditions.
35 citations
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January 2013 in “The Journal of experimental medicine/The journal of experimental medicine” CD98hc's role in skin health decreases with age.
34 citations
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April 2009 in “Skin Pharmacology and Physiology” Minoxidil affects cell growth in two ways: low doses increase growth, while high doses slow it down and can be toxic.
33 citations
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October 2016 in “European Journal of Pharmaceutical Sciences” Effervescent formulations may improve minoxidil delivery, increasing effectiveness and reducing applications needed.
33 citations
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February 2016 in “Journal of Experimental Botany” ROOT HAIR SPECIFIC 10 (RHS10) reduces the length of root hairs in Arabidopsis plants.
33 citations
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December 2012 in “NMR in Biomedicine” Microencapsulation helps protect and track therapeutic cells, showing promise for treating various diseases, but more work is needed to improve the technology.
32 citations
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March 2013 in “Journal of Pharmaceutical Sciences” Iontophoresis improves minoxidil delivery for alopecia treatment.
32 citations
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February 1998 in “The journal of investigative dermatology/Journal of investigative dermatology” Two specific hair keratin genes are active during hair growth and decline as hair transitions to rest.
31 citations
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October 2017 in “Dermatologic Surgery” Hair transplants look natural, but the best method is debated, and PRP shows promise for hair regrowth.
31 citations
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April 2016 in “Nature communications” Certain signals are important for reducing specific chemical markers on hair follicle stem cells during rest periods, which is necessary for healthy hair growth.
30 citations
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October 2020 in “Nature Communications” Finasteride irreversibly affects human steroid 5α-reductase 2, providing insight into its catalytic mechanism and disease-related mutations.
29 citations
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February 2018 in “European Journal of Immunology” Regulatory T cells are essential for normal and improved wound healing in mice.
29 citations
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October 2016 in “Cell death and differentiation” ΔNp63α stops TAp73β from working in skin cancer by blocking its access to specific genes, not by directly interacting with it.
29 citations
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March 2016 in “Cell cycle/Cell cycle (Georgetown, Tex. Online)” Isoproterenol helps hair follicle stem cells turn into beating heart muscle cells.