45 citations
,
June 2008 in “Journal of pharmaceutical and biomedical analysis” The method effectively identifies banned substances in hair loss and skin disease cosmetics.
4 citations
,
January 1982 in “Endocrinologia Japonica” Androgens regulate 5 alpha-reductase activity in hamster sebaceous glands.
April 2017 in “Actas urológicas españolas” 5-alpha reductase inhibitors increase the risk of sexual dysfunction in patients treating enlarged prostate but not in those treating hair loss.
Cyproterone acetate is an effective treatment for women with acne, hair loss, and excessive hair growth.
Antiandrogen treatment helps reduce hair follicles and sebaceous glands in hirsute women.
11 citations
,
May 1996 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” The main enzyme found in pubic skin that could be targeted to treat excessive hair growth is 5 alpha-R2.
22 citations
,
September 1994 in “The Journal of Clinical Endocrinology and Metabolism” Finasteride reduces dihydrotestosterone, increases testosterone, and may treat hirsutism in women.
August 2016 in “Journal of Investigative Dermatology”
2 citations
,
May 2021 in “Journal of pharmaceutical and biomedical analysis” A new method was developed to accurately detect and measure 47 different drug ingredients in various products.
65 citations
,
April 2002 in “Journal of Alternative and Complementary Medicine” Plant extracts effectively reduce hair loss and increase growth, offering a safe alternative treatment.
June 2013 in “NATIONS UNIVERSITY INTERNATIONAL JOURNAL OF MULTI-DISCIPLINARY STUDIES” Hyperandrogenism did not affect sexual function in young women.
10 citations
,
March 2023 in “Journal of Chemistry” New compounds show promise for treating benign prostate hyperplasia with fewer side effects.
35 citations
,
January 2014 in “Postepy Dermatologii I Alergologii” DHT's role in hair loss is important, but measuring its level for diagnosis is questionable.
60 citations
,
December 1998 in “Clinical Pharmacology & Therapeutics” Both drugs lower DHT levels, with GI198745 being more effective.
49 citations
,
October 1988 in “The Journal of Clinical Endocrinology & Metabolism” Leuprolide effectively reduces hair growth in hirsute women at higher doses.
13 citations
,
July 2008 in “Biomedical Chromatography” The methods accurately measured brain androgens, showing most 5α-androstane-3α,17β-diol comes from outside the brain, while androsterone is both transported and made in the brain.
January 2014 in “theses.fr (ABES)” Androgens regulate Sertoli cells and affect fertility through specific receptors and coregulators.
8 citations
,
June 2016 in “Clinical Chemistry” PSA levels could help detect illegal steroid use in female athletes but face challenges like cost and PCOS prevalence.
3 citations
,
November 2022 in “Separations” The method accurately measures seven androgens in plasma and shows different hormone levels in females with acne and obesity.
January 1995 in “Adolescent and pediatric gynecology” Mutations in the androgen receptor gene cause different levels of androgen insensitivity, making it hard to create simple tests for the condition.
2 citations
,
December 2016 in “Journal of Pakistan Association of Dermatology” Higher androgen levels are linked to more severe hair growth in hirsute women.
27 citations
,
November 2013 in “Dermatologic Therapy” New test predicts if hair loss treatment will work.
10 citations
,
August 1998 in “Journal of Investigative Dermatology” The compounds tested could potentially treat hair loss and alopecia.
5 citations
,
February 1997 in “Bioorganic & Medicinal Chemistry” New compounds were made that effectively block a specific enzyme related to androgen conditions.
September 2025 in “Journal of Medicinal Chemistry” AR-27 E-Chol siRNA can effectively regrow hair by reducing androgen receptor gene activity.
January 2014 in “edoc (University of Basel)” Anabolic steroids and inflammation can disrupt androgen metabolism, potentially causing health issues.
7 citations
,
May 2007 in “PubMed” Women with androgenetic alopecia (AGA) are more insulin resistant than healthy women, with various insulin sensitivity indices being higher in the AGA group. An oral glucose tolerance test is suggested for women with AGA.
January 1983 in “Elsevier eBooks” Masculinization in affected individuals occurs gradually after puberty due to hormone changes.
1 citations
,
October 2017 in “Elsevier eBooks” Antiandrogens can treat female hormonal conditions, but environmental ones may harm reproductive health.
December 2023 in “Biointerface Research in Applied Chemistry” Stiripentol shows promise as a potential treatment for androgen-related diseases but needs more testing.