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Scientists made the first metal-based compounds from a nonsteroidal antiandrogen drug, which showed potential in fighting both hormone-dependent and independent prostate cancer cells.

Human and horse hair have similar end groups to wool and feathers.

Certain enzymes react strongly with some hormones in rat skin during hair growth, mainly in sebaceous glands and hair sheaths.

Modified steroidal inhibitors showed promise in treating hormone-dependent cancers.

New compounds with carborane showed anti-androgen effects similar to flutamide.

The more lipophilic the progesterone derivative, the better it binds to androgen receptors and has antiandrogenic effects.

Two new compounds can block androgen receptor activity in different ways and may lead to new treatments for androgen-related diseases.

SARM-induced changes in the androgen receptor are specific to each ligand and affect stability and protein interactions.

Certain histamine receptors (H2R, H3R, H4R) have unique roles in treating skin diseases, with H2R helping with chronic urticaria and other conditions, H3R providing pain relief and allergy benefits, and H4R reducing inflammation and itchiness.

The compound 4c showed strong potential as an anticancer agent.

The tested hair dye ingredients do not form harmful oxidized metabolites in the liver.

The document concludes that scientists created various steroids with different properties, including a more effective semi-synthetic vitamin D.

Certain hydroxycinnamate derivatives may effectively inhibit enzymes linked to hair loss with low toxicity.

Analog 23 is a promising compound for prostate cancer treatment.

Researchers developed new compounds that target the androgen receptor effectively with fewer side effects.

Compound 15a was effective in inhibiting 5α-reductase.

Different halogens on progesterone derivatives can either block or mimic male hormone effects, depending on their type and amount.

A rigid compound with a common structural motif was successfully synthesized.

New compounds were made and tested, with compound 6 showing potential for treating prostate-related diseases.

Mutations in certain receptors can cause diseases and offer new treatment options.

SARMs work differently in tissues due to unique interactions and structures.

New progesterone-based compounds can block male hormones.

1,2,3,4-tetrahydroquinoline compounds are great for stable, pure blue hair dye.

A new compound effectively inhibits human 5α-reductase 1.

Iron chloride helps create compounds that could be useful in medicine, like treating hair loss.

A new compound with strong antiandrogenic effects was found, potentially useful for treating conditions like acne and prostate cancer.

CYP154C7 enzyme can effectively modify steroids and is promising for commercial use.

Compounds 6f and 6g effectively stop prostate cancer cell growth without harming healthy cells.

Three genes in Arabidopsis are important for plant growth and development by affecting sugar attachment to proteins.

RXR and RAR proteins in skin may help with cell growth, hair growth, and gland function.