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research Immunhistochemische und biochemische Untersuchungen zur Expression von epithelialen Keratinen in klinisch unveränderter Pferdehaut und Fußhaut von Kaltblutpferden mit Warzenmauke-Syndrom

January 2007

Diseased horse foot skin shows increased keratin expression, similar to wound healing in mammals.

research Mutations in Homocysteine Metabolism Genes Increase Keratin N-Homocysteinylation and Damage in Mice

5 citations , September 2018 in “International journal of genomics”

Genetic mutations that disrupt homocysteine breakdown lead to increased damage in mouse hair keratin.

research [Analysis of normal human hair keratins by two-dimensional polyacrylamide gel electrophoresis].

May 1988 in “PubMed”

research A gene for pachyonychia congenita is closely linked to the keratin gene cluster on 17q12-q21.

61 citations , September 1994 in “Journal of Medical Genetics”

Pachyonychia congenita is linked to a keratin gene on chromosome 17.

Structural and Biochemical Changes Underlying a Keratoderma-Like Phenotype in Mice Lacking Suprabasal AP1 Transcription Factor Function

research Structural and biochemical changes underlying a keratoderma-like phenotype in mice lacking suprabasal AP1 transcription factor function

17 citations , February 2015 in “Cell Death and Disease”

Inhibiting AP1 in mice skin causes structural changes and weakens the skin barrier.

research Synthesis of porcine pCLCA2 protein during late differentiation of keratinocytes of epidermis and hair follicle inner root sheath

13 citations , September 2012 in “Cell & tissue research/Cell and tissue research”

pCLCA2 protein may help maintain skin structure and function.

research A new mutation in the type II hair cortex keratin hHb1 involved in the inherited hair disorder monilethrix

100 citations , November 1997 in “Human Genetics”

A new mutation in the hHb1 keratin gene is linked to the hair disorder monilethrix.

research A Group of Type I Keratin Genes on Human Chromosome 17: Characterization and Expression

38 citations , February 1988 in “Molecular and Cellular Biology”

Only one of the two K16 genes on chromosome 17 makes a functional protein for keratin filaments.

research In this Issue

May 2002 in “Journal of Investigative Dermatology”

New findings on hair keratin, wound healing, and skin blistering were presented.

research An Unusual Ala12Thr Polymorphism in the 1A α-Helical Segment of the Companion Layer-Specific Keratin K6hf: Evidence for a Risk Factor in the Etiology of the Common Hair Disorder Pseudofolliculitis Barbae

88 citations , March 2004 in “Journal of Investigative Dermatology”

research De novo mutations in monilethrix

26 citations , December 2003 in “Experimental Dermatology”

Specific keratin gene mutations can cause monilethrix.

research Special Biochemical Features of the Hair Follicle

15 citations , January 1988

Hair follicles have unique proteins that vary by species and are influenced by nutrition.

research Delayed-onset pachyonychia congenita caused by a novel mutation in the V2 domain of keratin 6b

4 citations , December 2013 in “The Journal of Dermatology”

A new mutation in the K6b gene caused a girl's late-appearing nail condition.

research K6irs1, K6irs2, K6irs3, and K6irs4 Represent the Inner-Root-Sheath-Specific Type II Epithelial Keratins of the Human Hair Follicle1

130 citations , April 2003 in “Journal of Investigative Dermatology”

Four specific keratins in hair follicles help understand hair structure and function.

research Human Trichohyalin Gene Is Clustered with the Genes for Other Epidermal Structural Proteins and Calcium-Binding Proteins at Chromosomal Locus 1q21

January 1993

The trichohyalin gene is located at chromosomal region 1q21 with other skin-related protein genes.

research Mice Expressing a Mutant Krt75 (K6hf) Allele Develop Hair and Nail Defects Resembling Pachyonychia Congenita

46 citations , September 2007 in “Journal of Investigative Dermatology”

research cDNA Cloning, Expression, and Assembly Characteristics of Mouse Keratin 16

32 citations , November 1998 in “Journal of Biological Chemistry”

Mouse and human keratin 16 can both form filaments, with differences likely due to the tail domain, not the helical domain.

research Genomic Organization and Amplification of the Human Keratin 15 and Keratin 19 Genes

12 citations , January 2000 in “Biochemical and Biophysical Research Communications”

The study mapped keratin 15 and 19 genes, aiding future genetic disorder research.

research Keratin 16 Expression Defines a Subset of Epithelial Cells During Skin Morphogenesis and the Hair Cycle

87 citations , November 2002 in “Journal of Investigative Dermatology”

research Characterizing Wool Keratin

69 citations , January 2009 in “Advances in Materials Science and Engineering”

Wool keratin is reactive, biocompatible, biodegradable, and can model keratin from other sources.

research Investigating the role of keratin proteins and microbial associations in hereditary and pathogenic alopecia

October 2024 in “Archives of Dermatological Research”

research Ultrastructural localization of hair keratin homologs in the claw of the lizard Anolis carolinensis

20 citations , December 2010 in “Journal of Morphology”

Lizard claws have hair-like keratins similar to those in mammals.

research Culture of hair matrix and follicular keratinocytes

26 citations , July 1993 in “Journal of Investigative Dermatology”

research Characterization of a Hair (Wool) Keratin Intermediate Filament Gene Domain

40 citations , February 1994 in “Journal of Investigative Dermatology”

research Isolation and characterization of a sheep cysteine-rich cuticle keratin pseudogene

1 citations , January 1992 in “DNA sequence”

Researchers found a non-functional sheep keratin gene due to mutations.

research Expression of type I hair keratins in follicular tumours

26 citations , May 2001 in “British Journal of Dermatology”

Pilomatrixomas likely originate from the hair matrix due to changes in hair keratin expression.

research Seborrheic Keratoses and Trichostasis Spinulosa

26 citations , December 1979 in “Journal of Cutaneous Pathology”

Seborrheic keratoses may partly come from hair follicle cells.

research 1375 Cutaneous adnexal cysts revisited: A novel classification based on morphological and molecular features

April 2018 in “Journal of Investigative Dermatology”

The conclusion introduces a new way to classify skin cysts using their shape and genetic markers.

research A cDNA encoding the human type I hair keratin hHa1

20 citations , October 1995 in “Biochimica et Biophysica Acta (BBA) - Gene Structure and Expression”

hHb1, hHb3, and hHb6 mRNAs start expressing at the same time in hair follicles.

research Mammalian keratin associated proteins (KRTAPs) subgenomes: disentangling hair diversity and adaptation to terrestrial and aquatic environments

65 citations , September 2014 in “BMC genomics”

Different hair types in mammals are linked to variations in specific protein genes, with changes influenced by their living environments.

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