8 citations
,
March 2014 in “American Journal of Pathology” Damaged hair follicles make mice more prone to skin inflammation and skin cancer after UV exposure.
7 citations
,
March 2012 in “Journal of Investigative Dermatology” Some thymic peptides can increase human hair growth, while others may inhibit it.
288 citations
,
January 2001 in “Journal of Biological Chemistry” Tgm2 helps stabilize dying cells and aids fibroblast attachment to the extracellular matrix.
103 citations
,
November 2014 in “Journal of Cell Biology” MicroRNA-214 is important for skin and hair growth because it affects the Wnt pathway.
42 citations
,
July 2014 in “Journal of biological chemistry/The Journal of biological chemistry” Heparan sulfate is important for hair growth, preventing new hair formation in mature skin, and controlling oil gland development.
2 citations
,
May 2017 in “InTech eBooks” Stem cells could improve hair growth and new treatments for baldness are being researched.
1 citations
,
June 2025 in “Frontiers in Bioengineering and Biotechnology” Glycopeptide hydrogels are promising for tissue repair, drug delivery, and healing due to their multifunctional properties.
1 citations
,
September 2024 in “Frontiers in Cell and Developmental Biology” Pigs are a good model for studying human hair growth and disorders.
March 2021 in “bioRxiv (Cold Spring Harbor Laboratory)” Removing a specific gene in certain skin cells causes hair loss on the body by disrupting normal hair development.
98 citations
,
July 2014 in “Trends in Molecular Medicine” Hair follicles are hormone-sensitive and involved in growth and other functions, with potential for new treatments, but more research is needed.
316 citations
,
June 2004 in “The journal of investigative dermatology/Journal of investigative dermatology” Microspheres about 1.5 micrometers in size can best penetrate hair follicles, potentially reaching important stem cells.
April 2018 in “Journal of Investigative Dermatology” Glycogen metabolism is important for energy and processes in human hair follicles, and hair follicles may produce glucose from lactate.
30 citations
,
December 2018 in “Trends in Endocrinology and Metabolism” Both immature and mature fat cells are important for hair growth cycles, with immature cells promoting growth and mature cells possibly inhibiting it.
89 citations
,
September 2010 in “Annual Review of Genomics and Human Genetics” The document concludes that understanding the genes and pathways involved in hair growth is crucial for developing treatments for hair diseases.
39 citations
,
August 2018 in “Scientific reports” Claudin-1 is important for the barrier function and growth of hair.
28 citations
,
September 2013 in “Journal of Investigative Dermatology” The document concludes that dermal papilla cells are key for hair growth and could be used in new hair loss treatments.
4 citations
,
April 2010 in “Expert review of dermatology” Restoring immune privilege in hair follicles could help treat certain types of hair loss.
April 2024 in “bioRxiv (Cold Spring Harbor Laboratory)” GRK2 is essential for healthy hair follicle function, and its absence can lead to hair loss and cysts.
September 2018 in “Cosmetics” Inositol and arginine solutions improve hair follicle health and turnover.
14 citations
,
February 2021 in “Experimental Dermatology” Cannabinoid receptor-1 signaling is essential for the survival and growth of human hair follicle stem cells.
7 citations
,
January 2013 in “BioMed research international” Hair follicles and deer antlers regenerate similarly through stem cells and are influenced by hormones and growth factors.
81 citations
,
October 2014 in “The journal of investigative dermatology/Journal of investigative dermatology” Certain genes control the color of human hair by affecting pigment production.
75 citations
,
October 2016 in “Genes & Development” Cells in hair follicles help create fat cells in the skin by releasing a protein called Sonic Hedgehog.
30 citations
,
October 2021 in “Scientific Reports” Inhibiting glycogen metabolism can promote hair growth.
28 citations
,
March 2017 in “Endocrinology” Removing vitamin D and calcium receptors in mice skin cells slows down skin wound healing.
23 citations
,
January 2020 in “Frontiers in Pharmacology” Dihydrotestosterone affects hair growth by changing the Wnt/β-catenin pathway, with low levels helping and high levels hindering growth.
18 citations
,
October 2018 in “Nutrients” Annurca apple extract promotes hair growth by changing hair follicle metabolism to boost keratin production.
18 citations
,
September 2003 in “The journal of investigative dermatology/Journal of investigative dermatology” VDUP1 is found in skin and hair follicles, interacts with sciellin, and may help regulate skin cell differentiation.
April 2020 in “bioRxiv (Cold Spring Harbor Laboratory)” Skin healing from blisters can delay hair growth as stem cells focus on repairing skin over developing hair.
April 2018 in “The journal of investigative dermatology/Journal of investigative dermatology” Researchers created a 3D-printed skin model that grew human hair when grafted onto mice by improving blood supply to the grafts.