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research Identification of the C-terminal tail domain of AHF/trichohyalin as the critical site for modulation of the keratin filamentous meshwork in the keratinocyte

12 citations , December 2011 in “Journal of Dermatological Science”

The C-terminal tail of AHF/trichohyalin is essential for organizing keratin filaments in keratinocytes.

research KRT72 wt Allele

February 2020 in “Definitions”

KRT72 gene helps form hair.

Male Pattern Hair Loss: The Selfless Gene

research Male pattern hair loss: Taking one for the team: The selfless gene

February 2018 in “Medical Hypotheses”

Male pattern hair loss may have evolved to promote younger fathers for offspring health and survival, encouraging monogamy and paternal nurturing.

research EZH2-mediated inhibition of microRNA-22 promotes differentiation of hair follicle stem cells by elevating STK40 expression

12 citations , July 2020 in “Aging”

The protein EZH2 blocks microRNA-22, increasing STK40 protein, which helps hair follicle stem cells change and grow hair.

research Hair follicle aging is driven by transepidermal elimination of stem cells via COL17A1 proteolysis

8 citations , April 2017 in “Journal of Dermatological Science”

Hair loss is caused by the breakdown of a protein called COL17A1 in hair follicle stem cells.

DMBA/TPA Treatment Is Necessary for Basal Cell Carcinoma Formation from Patched Deficient Epidermal Cells in Ptch Flox/Flox CD4Cre +/- Mice

research DMBA/TPA Treatment Is Necessary for BCC Formation from Patched Deficient Epidermal Cells in Ptch flox/flox CD4Cre +/− Mice

11 citations , March 2014 in “Journal of Investigative Dermatology”

Genetic mutation and carcinogen treatment are both needed for skin cancer to develop in these specific mice.

research High-Throughput Sequencing Reveals miRNAs Affecting Follicle Development in Chicken

2 citations , January 2017 in “International journal of genetics and genomics”

Certain miRNAs are linked to chicken feather development.

research The Role of Histone Demethylases in Disease

1 citations , January 2011 in “Springer eBooks”

Histone demethylases play a key role in the development of many diseases and may be targets for treatment.

research Careless talk costs lives: fibroblast growth factor receptor signalling and the consequences of pathway malfunction

119 citations , November 2014 in “Trends in Cell Biology”

Fibroblast growth factor receptor signaling controls cell development and repair, and its malfunction can cause disorders and cancer, but it also offers potential for targeted therapies.

research Biological significance of FoxN1 gain-of-function mutations during T and B lymphopoiesis in juvenile mice

16 citations , October 2014 in “Cell death and disease”

FoxN1 overexpression in young mice harms immune cell and skin development.

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