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research De novo filament formation by human hair keratins K85 and K35 follows a filament development pattern distinct from cytokeratin filament networks

2 citations , February 2021 in “FEBS open bio”

Human hair keratins K85 and K35 create unique filament patterns important for early hair formation.

Characterization and Chromosomal Localization of Human Hair-Specific Keratin Genes and Comparative Expression During the Hair Growth Cycle

research Characterization and Chromosomal Localization of Human Hair-Specific Keratin Genes and Comparative Expression During the Hair Growth Cycle

32 citations , February 1998 in “The journal of investigative dermatology/Journal of investigative dermatology”

Two specific hair keratin genes are active during hair growth and decline as hair transitions to rest.

research Structural Stability of Wild Type and Mutated α-Keratin Fragments: Molecular Dynamics and Free Energy Calculations

40 citations , September 2004 in “Biomacromolecules”

The Glu413Lys mutation in keratin affects hair stability, while Glu413Asp does not.

research Protein chains in hair and epidermal keratin IF: Structural features and spatial arrangements

5 citations , January 1997 in “Birkhäuser Basel eBooks”

research Physiological roles of hair structural protein: a possible application of keratin-associated proteins to new hair growing ingredient

December 2007 in “FJ. Fragrance journal”

research Keratin disorders: from gene to therapy

109 citations , September 2011 in “Human molecular genetics online/Human molecular genetics”

New treatments targeting specific genes show promise for treating keratin disorders.

research Existence of trichohyalin-keratohyalin hybrid granules: Co-localization of two major intermediate filament-associated proteins in non-follicular epithelia

54 citations , November 1994 in “Differentiation”

Trichohyalin is found in non-hair tissues and works with filaggrin in certain skin areas and conditions.

research In vivo formation steps of the hard α-keratin intermediate filament along a hair follicle: Evidence for structural polymorphism

22 citations , January 2006 in “Journal of Structural Biology”

Hair follicles form hard α-keratin filaments in four steps, showing structural differences.

research Fine Structure of the Fully Keratinized Hair Cuticle in the Head Hair of the Human

11 citations , January 1981 in “Cells Tissues Organs”

Human hair cuticle has five cell layers with specific junctions and granules.

research Amino Acid as Hair Repair Agent: Unraveling its Mechanism of Interaction with Keratin

May 2026 in “Fibers and Polymers”

research A Unique Type I Keratin Intermediate Filament Gene Family is Abundantly Expressed in the Inner Root Sheaths of Sheep and Human Hair Follicles

41 citations , January 2001 in “Journal of Investigative Dermatology”

research Type II Epithelial Keratin 6hf (K6hf) Is Expressed in the Companion Layer, Matrix, and Medulla in Anagen-Stage Hair Follicles

60 citations , December 2003 in “Journal of Investigative Dermatology”

K6hf is found in specific parts of hair follicles, nails, and tongue, and is linked to hair growth and structure.

research Hair keratin molecular dynamics models

March 2016 in “RepositóriUM (Universidade do Minho)”

Molecular dynamics simulations help understand keratin's properties and predict hair's response to treatments.

research Keratohyalin, Trichohyalin and Keratohyalin‐Trichohyalin Hybrid Granules: An Overview

30 citations , November 1992 in “The Journal of Dermatology”

Keratohyalin and trichohyalin proteins help form and organize skin and hair structures.

research Structural Hierarchy of Trichocyte Keratin Intermediate Filaments

15 citations , January 2018 in “Advances in experimental medicine and biology”

Keratin proteins are crucial for hair growth and structure.

research The Viscoelastic Properties of Chemically Modified alpha-Keratins in Human Hair

1 citations , June 2014 in “[Thesis]. Manchester, UK: The University of Manchester; 2014.”

Chemical modifications can alter hair's stability and flexibility, with hydrophobic interactions helping maintain structure in humid conditions.

research Keratins of the Human Hair Follicle

276 citations , January 2005 in “International review of cytology”

More research is needed to understand how hair keratins work and their role in hair disorders.

research Hair keratin film as a substitute device for human hair

10 citations , January 2012 in “Journal of Biological Macromolecules”

Keratin film can effectively replace human hair for testing hair damage.

research Outer root sheath keratinization in anagen and catagen of the mammalian hair follicle. A seventh distinct type of keratinization in the hair follicle: trichilemmal keratinization.

59 citations , August 1981 in “PubMed”

Trichilemmal keratinization is a unique process in hair follicles where the outer root sheath turns into keratin without a specific layer.

research Directed Expression of a Chimeric Type II Keratin Partially Rescues Keratin 5-null Mice

15 citations , May 2014 in “Journal of Biological Chemistry”

A chimeric keratin partially improved skin structure in mice lacking keratin 5, but didn't fully restore normal skin.

research [Analysis of normal human hair keratins by two-dimensional polyacrylamide gel electrophoresis].

May 1988 in “PubMed”

research Mechanical and biological properties of keratose biomaterials

140 citations , August 2011 in “Biomaterials”

Keratose, derived from human hair, is a non-toxic biomaterial good for tissue regeneration and integrates well with body tissues.

research The structure of the “amorphous” matrix of keratins

30 citations , April 2017 in “Journal of structural biology”

Human hair keratin fibers have a detailed nano-scale structure that changes with different conditions.

research Identification of two novel clusters of ultrahigh-sulfur keratin-associated protein genes on human chromosome 11*1

1 citations , May 2004 in “Biochemical and Biophysical Research Communications”

Two new gene clusters important for hair formation were found on human chromosome 11.

research Penetration of different molecular weight hydrolysed keratins into hair fibres and their effects on the physical properties of textured hair

7 citations , September 2020 in “International Journal of Cosmetic Science”

Different sizes of keratin peptides can strengthen hair, with smaller ones possibly increasing volume and larger ones repairing damage.

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