February 2025 in “bioRxiv (Cold Spring Harbor Laboratory)” Keratin 15 helps keep skin cells in a young, undifferentiated state.
3 citations
,
June 2020 in “Developmental Cell” Feather patterns are influenced by enhancers and chromatin looping, and the structure of protein complexes important for hair growth has been detailed.
33 citations
,
October 2012 in “Journal of Morphology” Reptile skin hardens by layering beta-proteins on keratin.
41 citations
,
December 2011 in “The journal of investigative dermatology/Journal of investigative dermatology” Deleting MED1 in skin cells causes hair loss and skin changes.
3 citations
,
December 2008 in “Frontiers of Agriculture in China” The Cashmere goat hair keratin gene is crucial for hair structure.
7 citations
,
September 2020 in “International Journal of Cosmetic Science” Different sizes of keratin peptides can strengthen hair, with smaller ones possibly increasing volume and larger ones repairing damage.
August 2016 in “Journal of Investigative Dermatology” EZH2 is essential for hair growth and skin cell development.
18 citations
,
October 2009 in “Endocrinology” Different Hairless isoforms affect Vitamin D receptor activity in hair regulation, with one repressing and the other stimulating it.
January 2026 in “Biomaterials and Biosystems” Keratin from chicken feathers can be safely used on damaged skin.
5 citations
,
September 2011 in “Biochimica et Biophysica Acta (BBA) - Molecular Basis of Disease” Hairless protein helps control hair growth by regulating vitamin D receptor activity.
29 citations
,
July 2015 in “Journal of Medical Genetics” A genetic variant in the KRT25 gene causes tightly curled hair.
28 citations
,
April 1988 in “Archives of Dermatological Research” January 2026 in “Health Food & Biotechnology” A hair serum with 3% keratin from chicken feathers made hair smoother, shinier, and more elastic.
December 1991 in “Annals of the New York Academy of Sciences” Keratin proteins are crucial for hair structure and strength.
16 citations
,
September 2018 in “Scientific reports” Scientists created keratinocyte cell lines from human hair that can differentiate similarly to normal skin cells, offering a new way to study skin biology and diseases.
81 citations
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January 1987 in “Current topics in developmental biology/Current Topics in Developmental Biology” Keratins change and are modified differently in skin layers and body parts.
6 citations
,
June 2016 in “Journal of cellular biochemistry” The Hr protein binds to DNA, interacts with p53, and affects cell cycle genes.
34 citations
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July 1958 in “Biochimica et Biophysica Acta” 3 citations
,
December 2018 in “Routledge eBooks” Hair is made of strong keratin fibers that protect against the environment.
January 2002 in “Agritrop (Cirad)” The hr gene is linked to hair loss in Valle del Belice sheep.
177 citations
,
April 2008 in “Biomedical Materials” Human hair proteins can be used to create scaffolds that support cell growth for tissue engineering.
11 citations
,
September 2012 in “The journal of investigative dermatology/Journal of investigative dermatology” A mutation in the KRT71 gene causes a hair disorder by disrupting hair follicle structure and texture.
4 citations
,
August 2006 in “The Journal of Dermatology” HLA can be linked to autoimmune hepatitis.
140 citations
,
April 2004 in “The journal of investigative dermatology/Journal of investigative dermatology” The enzyme 25 Hydroxyvitamin D 1 α-Hydroxylase is essential for healthy skin and recovery after skin damage.
238 citations
,
May 1989 in “Journal of Investigative Dermatology” 25 citations
,
September 1995 in “Biochemistry and Cell Biology” High levels of human keratin 16 in mice cause skin lesions and abnormal skin development.
31 citations
,
March 1995 in “Journal of Investigative Dermatology” 482 citations
,
June 1979 in “Proceedings of the National Academy of Sciences” Keratins provide structural strength in epithelial cells and help identify cell origins.
44 citations
,
March 2012 in “Molecular Carcinogenesis” Keratin 15 cells from hair follicles help develop and maintain skin tumors in mice.
January 2002 in “Academic Journal of Kunming Medical College” Human-hair keratin artificial tendons are biocompatible and degrade well in rabbits.