January 2017 in “대한미용학회지” The cuticle layer in hair follicles thickens during keratinization due to incomplete cytosol loss.
198 citations
,
October 1986 in “Differentiation” 161 citations
,
June 1993 in “Journal of Biological Chemistry” Trichohyalin helps in hair and skin cell structure and function by binding calcium and linking proteins.
8 citations
,
April 2009 in “International journal of oncology” Hair follicle cells resist turning into skin cells.
July 2007 in “Manuals in biomedical research” 7 citations
,
January 2017 in “Sub-cellular biochemistry/Subcellular biochemistry” 31 citations
,
October 1992 in “PubMed” A mycobacterial protein shares a similar region with a human skin protein, possibly affecting skin diseases.
35 citations
,
September 1994 in “Journal of Investigative Dermatology” 186 citations
,
December 2012 in “Current opinion in cell biology” Keratin proteins are increasingly recognized as important for cell health and are linked to many diseases.
February 1985 in “PubMed” 22 citations
,
January 2006 in “Journal of Structural Biology” Hair follicles form hard α-keratin filaments in four steps, showing structural differences.
38 citations
,
February 1988 in “Molecular and Cellular Biology” Only one of the two K16 genes on chromosome 17 makes a functional protein for keratin filaments.
25 citations
,
October 1962 in “Journal of Ultrastructure Research” The hair follicle structure is more complex than thought, with new findings on protein formation.
60 citations
,
March 2006 in “Journal of Medical Genetics” A mutation in the KRTHB5 gene causes hair and nail issues.
57 citations
,
January 1987 in “Journal of Biological Chemistry” Different keratins have unique expression patterns in mouse skin cells.
13 citations
,
July 2017 in “Biopolymers” Recombinant keratins can form useful structures for medical applications, overcoming natural keratin limitations.
88 citations
,
March 2004 in “Journal of Investigative Dermatology” 23 citations
,
January 1981 Hair is mostly made of three protein types: helical, high-sulfur, and high-tyrosine.
15 citations
,
January 2018 in “Advances in experimental medicine and biology” Keratin proteins are crucial for hair growth and structure.
10 citations
,
November 2013 in “Biochemistry and Molecular Biology Education” Keratins are crucial proteins for hair and nails, with a structure that helps teach protein principles.
276 citations
,
January 2005 in “International review of cytology” More research is needed to understand how hair keratins work and their role in hair disorders.
5 citations
,
January 1997 in “Birkhäuser Basel eBooks” 13 citations
,
May 2001 in “Current problems in dermatology” Keratin proteins in epithelial cells are dynamic and crucial for cell processes and disease understanding.
19 citations
,
December 2006 in “Journal of Structural Biology” Type I and Type II keratin chains can form heterodimers despite sequence differences.
25 citations
,
September 1995 in “Biochemistry and Cell Biology” High levels of human keratin 16 in mice cause skin lesions and abnormal skin development.
130 citations
,
April 2003 in “Journal of Investigative Dermatology” Four specific keratins in hair follicles help understand hair structure and function.
54 citations
,
November 1994 in “Differentiation” Trichohyalin is found in non-hair tissues and works with filaggrin in certain skin areas and conditions.
13 citations
,
November 2007 in “Journal of Structural Biology” Keratin heterodimers are preferred for their specific and structural advantages.
The trichohyalin gene is located at chromosomal region 1q21 with other skin-related protein genes.