256 citations
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October 2013 in “Proceedings of the National Academy of Sciences of the United States of America” Growing human skin cells in a 3D environment can stimulate new hair growth.
248 citations
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December 2011 in “Journal of Neuroscience” Neurosteroids are crucial for stress response, and targeting specific receptors may help treat certain disorders.
245 citations
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January 2018 in “Bone Research” TGF-β is crucial for tissue repair and can cause diseases if not properly regulated.
228 citations
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January 2021 in “Journal of Neuroimmune Pharmacology” Men have more severe COVID-19 outcomes than women.
218 citations
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December 2011 in “Advances in Urology” The document concludes that the 5 alpha-reductase enzymes are important in steroid metabolism and related to various human diseases, with inhibitors used to treat conditions like male pattern baldness and prostate issues.
215 citations
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January 2011 in “Reproductive Biology and Endocrinology” About 7% to 15% of Iranian women have polycystic ovary syndrome, depending on the criteria used to diagnose it.
211 citations
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October 2001 in “The FASEB Journal” Noggin is necessary to start the hair growth phase in skin after birth.
205 citations
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April 2013 in “British Journal of Dermatology” Platelet-rich plasma treatment significantly increased hair regrowth and decreased discomfort in alopecia patients, making it a potentially better and safer treatment option.
202 citations
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August 2017 in “Nature cell biology” Lactate production is important for activating hair growth stem cells.
198 citations
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October 2011 in “Journal der Deutschen Dermatologischen Gesellschaft” Use minoxidil for hair loss; finasteride and dutasteride for men, dutasteride for women.
195 citations
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May 2003 in “Obstetrics and gynecology (New York. 1953. Online)/Obstetrics and gynecology” Most women with excess hair growth have an underlying hormonal issue, often treated with medication and hair removal methods.
192 citations
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January 2015 in “Journal of the American Academy of Dermatology” Targeted cancer therapies often cause serious skin problems that need careful management.
191 citations
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September 2011 in “Cell stem cell” Hair follicle stem cells use specific chromatin changes to control their growth and differentiation.
186 citations
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July 1998 in “Journal of Cutaneous Medicine and Surgery” Shorter CAG repeats may cause hair and skin issues, while longer ones may link to acne.
184 citations
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August 1983 in “The journal of pediatrics/The Journal of pediatrics” Biotinidase deficiency has various symptoms and can be treated with biotin supplements.
182 citations
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December 2007 in “BJCP. British journal of clinical pharmacology/British journal of clinical pharmacology” Hair follicles significantly increase the speed and amount of caffeine absorbed through the skin.
180 citations
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January 2003 in “American Journal of Clinical Dermatology” Menopause can lead to skin and hair problems due to hormonal changes, but hormone replacement therapy might help slow these effects.
178 citations
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May 2006 in “Developmental Dynamics” Jumonji genes are important for development and their mutations can cause abnormalities, especially in the heart and brain.
176 citations
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August 2015 in “The journal of allergy and clinical immunology/Journal of allergy and clinical immunology/The journal of allergy and clinical immunology” Alopecia areata involves immune activation in the scalp, suggesting treatments targeting TH1, TH2, and IL-23 pathways.
168 citations
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December 1986 in “Cancer Chemotherapy and Pharmacology” Epirubicin is as effective as doxorubicin for cancer treatment with less heart damage, but doesn't work on doxorubicin-resistant cancers.
165 citations
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June 2007 in “European Journal of Cell Biology” Hair follicle stem cells are key for hair and skin regeneration, can be reprogrammed, and have potential therapeutic uses, but also carry a risk of cancer.
164 citations
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January 2014 in “Journal of Cutaneous and Aesthetic Surgery” PRP injections increase hair density and satisfaction in androgenetic alopecia patients.
162 citations
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August 2005 in “The journal of investigative dermatology/Journal of investigative dermatology” The new "differential stripping" method effectively measures how much substance gets into hair follicles.
162 citations
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August 2002 in “Survey of Ophthalmology” Latanoprost can make eyelashes longer, thicker, and darker.
161 citations
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July 2003 in “ACM Transactions on Graphics” Researchers developed a new model for more realistic computer graphics rendering of hair by considering how light scatters on hair fibers.
159 citations
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July 2006 in “Endocrine Reviews” Estrogens significantly influence hair growth by interacting with receptors in hair follicles and may help regulate the hair growth cycle.
157 citations
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June 2011 Dermatoscopy and videodermatoscopy are useful for diagnosing and monitoring various skin, hair, and nail conditions.
152 citations
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April 2012 in “Recent Patents on Inflammation & Allergy Drug Discovery” Minoxidil treats hair loss, promotes growth, has side effects, and has recent patents.
152 citations
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December 2007 in “Gender Medicine” Male and female skin differ due to hormones, affecting conditions like hair loss, acne, and skin cancer, and suggesting a need for gender-specific treatments.
151 citations
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November 2018 in “International Journal of Pharmaceutics” Nanoparticles improve drug delivery through the skin but more research is needed on their long-term effects and skin penetration challenges.