April 2023 in “Journal of Investigative Dermatology” The study found that aging hair follicle stem cells change behavior, leading to hair loss, but drugs targeting these cells may help restore hair growth.
July 2023 in “Journal of bioscience and bioengineering” DMSO and microfinger devices show promise for preserving hair grafts for hair loss treatments.
March 2026 in “Journal of Investigative Dermatology” Folliculin slows hair growth, and blocking it might help treat hair loss.
August 2021 in “Journal of Investigative Dermatology” Stress causes hair loss by making the body produce cortisol, which stops hair cells from growing.
11 citations
,
June 1985 in “Journal of cutaneous pathology” Examining many sections is key to correctly diagnosing hair follicle disorders.
January 2022 in “Figshare” Melatonin affects when and how goat hair follicle genes turn on and off during growth cycles.
36 citations
,
October 1993 in “British Journal of Dermatology” Human hair follicles can grow in a lab for at least 9 days without serum, keeping their natural characteristics.
A 73-year-old woman's unusual hair loss and growth led to the discovery of a rare condition causing too much testosterone, which improved after her ovaries were removed.
120 citations
,
November 2014 in “Biological Reviews” The telogen phase of hair growth is active and important for preparing hair follicles for regeneration, not just a resting stage.
September 1997 in “JEADV. Journal of the European Academy of Dermatology and Venereology/Journal of the European Academy of Dermatology and Venereology” Blocking IL-1 could help treat some hair loss conditions; alopecia affects liver detox systems; spironolactone is better than finasteride for female hair growth; focusing on the catagen hair phase could lead to new alopecia treatments.
11 citations
,
October 1997 in “British Journal of Dermatology” Wool follicles grew fibres for 8-10 days in a serum-free culture, influenced by calcium, glucose, amino acids, and insulin.
19 citations
,
November 2001 in “Journal of Investigative Dermatology Symposium Proceedings” Human hair follicles can regenerate and recover after severe injury by going through a brief abnormal resting phase before growing again.
8 citations
,
September 2002 in “Genes to Cells” Killing specific cells in hair follicles can lead to hair growth problems in mice.
86 citations
,
February 2012 in “Journal of Clinical Investigation” Stem cells in hair follicles are diverse and change throughout the hair cycle.
5 citations
,
January 2023 in “International Journal of Molecular Sciences” Hair follicles could be used to noninvasively monitor our body's internal clock and help identify risks for related diseases.
40 citations
,
March 2017 in “The journal of investigative dermatology/Journal of investigative dermatology” Growing hair follicles have high mitochondrial activity and ROS in specific regions, aiding hair formation.
23 citations
,
July 1997 in “British Journal of Dermatology” The inner root sheath is vital for hair follicle stability during growth changes.
2 citations
,
April 2017 in “PubMed” Fat cells near hair follicles may affect hair growth and could help treat baldness.
75 citations
,
October 2016 in “Genes & Development” Cells in hair follicles help create fat cells in the skin by releasing a protein called Sonic Hedgehog.
September 2025 in “Digital Commons - RU (Rockefeller University)” FOXC1 is essential for keeping hair follicle stem cells inactive and maintaining their environment for healthy hair growth.
35 citations
,
November 2010 in “Journal of Cutaneous Pathology” Dilated follicular infundibula and increased catagen/telogen follicles are key indicators for diagnosing alopecia areata.
September 2017 in “Journal of Investigative Dermatology” Stabilizing HIF-1A in hair follicles may reduce oxidative stress and promote hair growth by increasing glycolysis.
April 2018 in “Journal of Investigative Dermatology” Older hair follicle stem cells have a reduced ability to renew themselves, leading to more hair loss.
7 citations
,
February 2003 in “Gynecological Endocrinology” Finasteride effectively reduces excess hair in women with certain conditions.
21 citations
,
April 2000 in “Journal of Cutaneous Pathology” The hamartoma is an abnormal hair growth with limited development in the upper hair follicle.
April 2018 in “Journal of Investigative Dermatology” Stabilizing HIF1A in hair follicles increases glycolysis, which may help reduce oxidative stress and support hair growth.
March 2014 in “Anais Brasileiros de Dermatologia” Hair follicles are a key source of stem cells for skin repair and could help treat baldness.
19 citations
,
July 2011 in “Microscopy and Microanalysis” The hair follicle bulge is an important area for adult stem cells involved in hair growth and repair, with potential for medical use needing more research.
January 2021 in “Research Square (Research Square)” Rabbits with high wool production have more hair follicles, influenced by specific long noncoding RNAs.
April 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” T cells with memory features grow in number and gather around hair follicles when there are not enough immune cells.