77 citations
,
February 2017 in “Stem Cell Reports” SHISA6 helps maintain certain stem cells in mouse testes by blocking signals that would otherwise cause them to differentiate.
70 citations
,
February 2012 in “Human Reproduction” Many young women who donate blood have hormonal disorders like excess male hormones and PCOS.
66 citations
,
December 2003 in “Endocrinology and Metabolism Clinics of North America” Doctors need to be better prepared to assess and treat obesity in patients.
66 citations
,
August 1999 in “The Journal of Clinical Endocrinology & Metabolism” Women with acromegaly often have irregular periods due to hormone imbalances and growth hormone effects.
61 citations
,
February 2001 in “American Journal of Obstetrics and Gynecology” Metabolic syndrome and PCOS are related but separate conditions, with metabolic syndrome increasing the risk of heart disease and diabetes.
59 citations
,
November 2018 in “Psychoneuroendocrinology” Lower levels of certain brain chemicals are linked to worse PTSD symptoms in men.
49 citations
,
May 2018 in “Endocrine” Women with regular menstrual cycles and PCOS have linked kisspeptin and LH hormone patterns, unlike those with irregular cycles.
48 citations
,
February 2014 in “Fertility and Sterility” Women with PCOS often have hair loss, which is linked to acne or excess body hair but not to worse hormone or metabolic issues.
47 citations
,
June 2016 in “JAMA Dermatology” Men with early hair loss have similar hormone levels to women with PCOS, possibly increasing risk of obesity and heart issues.
47 citations
,
June 2015 in “Medicines” Panax ginseng is generally safe with mild side effects and may have health benefits, but more research is needed.
46 citations
,
January 2007 in “The European Journal of Contraception & Reproductive Health Care” Birth control pills increase the risk of blood clots, especially within the first year and with certain types.
42 citations
,
August 2017 in “Human Reproduction” Women with polycystic ovary syndrome tend to have a longer distance between the clitoris and anus.
39 citations
,
January 2012 in “Reproductive Biology and Endocrinology” About 8.5% of women in Salvador, Brazil, have Polycystic Ovary Syndrome.
38 citations
,
February 2005 in “The journal of sexual medicine” The testosterone patch and gel are both effective, but they have different absorption patterns and effects on hormone levels.
35 citations
,
December 2009 in “Human reproduction” Metformin taken during pregnancy increases SHBG in newborns but doesn't change other hormone levels in mothers or babies.
34 citations
,
January 2008 in “International Review of Neurobiology” Epilepsy and certain epilepsy drugs can lead to reproductive problems in women, but changing medication might improve these issues.
32 citations
,
April 2016 in “Journal of Obstetrics and Gynaecology Research” Women with severe types of PCOS are more likely to have metabolic syndrome, and belly fat is a key predictor of this risk.
31 citations
,
September 2015 in “BJUI” Men with benign prostatic hyperplasia are more likely to have metabolic syndrome than those without it.
28 citations
,
August 2003 in “Steroids” Hirsute women have lower type 2 17β-HSD enzyme levels, which improve with treatment.
27 citations
,
October 2016 in “The Journal of Clinical Endocrinology and Metabolism” Daughters of women with PCOS generally experience normal puberty but may have more body hair and different body fat distribution.
25 citations
,
January 2022 in “Endocrine journal” Long COVID patients may have hormonal imbalances linked to their symptoms.
25 citations
,
December 2017 in “The Journal of Clinical Endocrinology & Metabolism” Birth control pills combined with bicalutamide are more effective at reducing excessive hair growth in women with PCOS than birth control pills alone.
25 citations
,
August 2006 in “Human Reproduction” Oral contraceptives lower testosterone levels in women, especially those with certain genetic traits, and may be linked to increased breast cancer risk.
22 citations
,
January 2015 in “BioMed Research International” More adolescent girls in urban areas of India have Polycystic Ovary Syndrome compared to those in rural areas.
21 citations
,
December 2012 in “Maturitas” Testosterone implants in women require pharmacological dosing to be effective and are generally safe and well-tolerated.
19 citations
,
March 2012 in “Clinical Endocrinology” FAI values above 6.4 may suggest high androgen levels and increased metabolic risks in Chinese women of reproductive age.
19 citations
,
January 2011 in “Obstetrics and gynecology international” Red clover extract improved hair, skin, mood, sleep, and tiredness in postmenopausal women.
17 citations
,
June 2010 in “Journal of Cosmetic Dermatology” Many women with hard-to-treat acne also have PCOS.
17 citations
,
December 2008 in “Dermatology” Taking metformin with intense-pulsed-light therapy improves hair removal for people with PCOS.
16 citations
,
March 2014 in “Journal of the European Academy of Dermatology and Venereology” Korean patients with PCOS often have skin problems like acne and excess hair, with different symptoms based on their specific PCOS type.