85 citations
,
January 2018 in “Cell stem cell” Different signals work together to change gene activity and guide hair follicle stem cells to become specific cell types.
January 2009 in “Bradford Scholars (University of Bradford)” BMP signaling helps prevent skin tumors by blocking cancer-promoting pathways.
July 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” Blocking mTORC1 activity with rapamycin could help increase hair pigmentation and growth, potentially reversing gray hair.
January 2022 in “Figshare” Melatonin affects when and how certain genes work during the different stages of hair growth in goats.
S1PR1 helps control inflammation in blood vessel cells by affecting gene activity differently in various cell types and locations.
May 2023 in “Pharmaceuticals” Three specific mutations in the LIPH gene can cause hair loss by damaging the protein's structure and function.
April 2019 in “Journal of Investigative Dermatology” Calcium signals and SHH guide the direction of feather growth in chicken skin.
January 2018 in “bioRxiv (Cold Spring Harbor Laboratory)” Researchers found key regions in the mouse hairless gene that control its activity in skin and brain cells, affecting hair follicle function.
74 citations
,
September 2006 in “Cell Cycle” The HR protein's role as a repressor is essential for controlling hair growth.
1 citations
,
February 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” A peptide from hair follicle stem cells promotes hair growth by activating specific skin cells.
26 citations
,
December 2017 in “Journal of Investigative Dermatology” Disrupting Notch signaling in blood vessels increases scarring during wound healing in mice.
31 citations
,
June 2021 in “Biomedicine & Pharmacotherapy” Liposomal honokiol helps hair regrowth by activating certain pathways and reducing specific proteins.
27 citations
,
June 2023 in “Nature” Senescent melanocytes can boost hair growth by activating hair stem cells.
26 citations
,
August 2019 in “Stem Cell Research & Therapy” PBX1 helps hair stem cells grow and change by turning on certain cell signals and preventing cell death, which may be useful for hair regrowth treatments.
February 2024 in “Frontiers in physiology” Modifying certain signals in the body can help wounds heal without scars and regrow hair.
7 citations
,
January 2020 in “The journal of investigative dermatology/Journal of investigative dermatology” NIPP1 is important for healthy skin and could help treat skin inflammation.
35 citations
,
July 2018 in “Cell Reports” The study found that a specific area of the hair follicle helps start hair growth by reducing the blocking effects on certain cells and controlling growth signals.
20 citations
,
February 2010 in “Journal of Investigative Dermatology” Slug (Snai2) helps regulate hair growth timing in mice.
Sox13 is a marker for early hair follicle development but not essential for skin and hair growth.
September 2019 in “Journal of Investigative Dermatology” BMPs are important for hair growth and can counteract the negative effects of androgens on hair follicle stem cells.
137 citations
,
September 2005 in “Proceedings of the National Academy of Sciences of the United States of America” The HR protein helps hair grow by blocking a hair growth inhibitor, aiding in hair follicle regeneration.
January 2024 in “Journal of cellular immunology” Hair follicle stem cells are important for maintaining healthy skin and interact with many signals.
November 2024 in “Research Square (Research Square)” Lipids may help treat hair loss by promoting hair growth through the HIF-1 pathway.
45 citations
,
August 2009 in “American Journal Of Pathology” Noggin promotes skin tumors by activating certain cell signaling pathways.
21 citations
,
September 2010 in “Cancer Prevention Research” Overactive signaling in hair follicles can lead to skin cancer.
79 citations
,
January 2002 in “Nucleic Acids Research” BMP-2 activates the Dlx3 gene in mouse skin cells, important for hair and skin development.
TLR2 helps control hair growth and regeneration, and its reduction with age or obesity can impair hair growth.
30 citations
,
February 2017 in “Histochemistry and Cell Biology” TPA promotes hair growth by increasing stem cell activity and activating specific cell signals.
April 2026 in “International Journal of Biological Macromolecules”