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Study of Human Leukocyte Antigen in 13 Cases of Familial Frontal Fibrosing Alopecia: CYP21A2 Gene p.V281L Mutation from Congenital Adrenal Hyperplasia Linked to HLA Class I Haplotype HLA-A*33:01; B*14:02; C*08:02 as a Genetic Marker

research Study of Human Leukocyte Antigen ( HLA ) in 13 cases of familial frontal fibrosing alopecia: CYP 21A2 gene p.V281L mutation from congenital adrenal hyperplasia linked to HLA class I haplotype HLA ‐ A33:01 ; B14:02; C*08:02 as a genetic marker

7 citations , January 2019 in “Australasian Journal of Dermatology”

A genetic marker linked to a type of hair loss was found in most patients studied.

research Identification of Pygopus 2 as a component of the ribosomal RNA transcription complex in cancer

January 2008 in “Memorial University Research Repository (Memorial University)”

Pygopus 2 helps ovarian cancer cells grow by aiding ribosomal RNA production, independent of Wnt signaling.

research Hypoxia inducible factor-1a promotes trichogenic gene expression in human dermal papilla cells

1 citations , November 2022 in “Research Square (Research Square)”

A protein called HIF-1a helps control hair growth genes and could be targeted to treat hair loss.

research Evidence for a functional interaction of WNT10A and EBF1 in male-pattern baldness

12 citations , September 2021 in “PLoS ONE”

WNT10A and EBF1 interaction affects hair growth in male-pattern baldness.

research Molecular evolution of HR, a gene that regulates the postnatal cycle of the hair follicle

9 citations , July 2011 in “Scientific Reports”

Changes in the HR gene have influenced hair growth and may lead to hair loss conditions in humans.

research Expression of apoptosis-related genes in the mouse skin during the first postnatal catagen stage, focused on localization of Bnip3L and caspase-12

4 citations , June 2015 in “Connective tissue research”

The research found changes in gene expression related to cell death in mouse skin that help understand hair follicle development and skin health.

research Topobiology of Human Pigmentation: P-Cadherin Selectively Stimulates Hair Follicle Melanogenesis

29 citations , January 2013 in “The journal of investigative dermatology/Journal of investigative dermatology”

P-cadherin is crucial for hair follicle pigmentation but not skin pigmentation.

research Hair Follicle Pluripotent Stem (hfPS) Cells

2 citations , January 2009 in “Human cell culture”

research Transient Expression of Mouse Hair Keratins in Transfected HeLa Cells: Interactions Between “Hard” and “Soft” Keratins

25 citations , August 1991 in “Journal of Investigative Dermatology”

The Peptide AC 2 Isolated from Bacillus-Treated Trapa Japonica Fruit Extract Rescues DHT-Treated Human Dermal Papilla Cells and Mediates mTORC1 Signaling for Autophagy and Apoptosis Suppression

research The peptide AC 2 isolated from Bacillus-treated Trapa japonica fruit extract rescues DHT (dihydrotestosterone)-treated human dermal papilla cells and mediates mTORC1 signaling for autophagy and apoptosis suppression

9 citations , November 2019 in “Scientific reports”

The AC 2 peptide from Trapa japonica fruit helps protect hair cells and may treat hair loss.

research Studies on the Proteome of Human Hair - Identification of Histones and Deamidated Keratins

54 citations , January 2018 in “Scientific reports”

Human hair contains diverse proteins, including keratins and histones, which could help assess hair health and aging.

Physiological Functions of PP2A: Lessons from Genetically Modified Mice

research Physiologic functions of PP2A: Lessons from genetically modified mice

87 citations , July 2018 in “Biochimica et Biophysica Acta (BBA) - Molecular Cell Research”

Mice studies show that Protein Phosphatase 2A is crucial for cell growth, development, and disease prevention.

research Bikunin, a Serine Protease Inhibitor, is Present on the Cell Boundary of Epidermis

13 citations , August 1999 in “Journal of Investigative Dermatology”

Bikunin is found on the cell boundaries of certain skin layers and may help regulate skin and hair functions.

research Two mouse mutations mapped to chromosome 11 with differing morphologies but similar progressive inflammatory alopecia

7 citations , May 2005 in “Experimental Dermatology”

Two mouse mutations cause similar hair loss despite different skin changes.

research Expression of hair-related keratins in a soft epithelium: Subpopulations of human and mouse dorsal tongue keratinocytes express keratin markers for hair-, skin- and esophageal-types of differentiation

128 citations , March 1989 in “Experimental Cell Research”

Hoxc13 is important for hair and tongue development by controlling hair keratin genes.

research Molecular studies of Hutchinson-Gilford progeria syndrome

May 2009 in “OPAL (Open@LaTrobe) (La Trobe University)”

Suppressing the HGPS mutation may improve symptoms and suggest reversibility.

research YAP1 promotes adipogenesis by regulating the negative feedback mechanism of the Hippo signaling pathway via LATS2

2 citations , January 2025 in “动物学研究”

YAP1 helps fat cell formation by influencing the Hippo pathway.

Double Knockdown of the Androgen Receptor Target Genes DKK1 and SFRP1 Does Not Potentiate the Hair Growth-Promoting Effect of SFRP1 Silencing in Healthy Human Hair Follicles Ex Vivo

research Double Knockdown of the Androgen Receptor Target Genes DKK1 and SFRP1 Does Not Potentiate the Hair Growth-Promoting Effect of SFRP1 Silencing in Healthy Human Hair Follicles Ex Vivo

February 2026 in “International Journal of Molecular Sciences”

Silencing SFRP1 alone promotes hair growth, but adding DKK1 does not help.

research Autosomal-Dominant Woolly Hair Resulting from Disruption of Keratin 74 (KRT74), a Potential Determinant of Human Hair Texture

97 citations , March 2010 in “The American Journal of Human Genetics”

A mutation in the KRT74 gene causes tightly curled hair.

research Keratinocyte-specific ablation of the NF-κB regulatory protein A20 (TNFAIP3) reveals a role in the control of epidermal homeostasis

76 citations , May 2011 in “Cell death and differentiation”

A20 protein is crucial for normal skin and hair development.

research Bone morphogenetic proteins 4 and 2/7 induce osteogenic differentiation of mouse skin derived fibroblast and dermal papilla cells

28 citations , November 2013 in “Cell and Tissue Research”

research Ribonucleic Acids Coding for the Keratin Complex of Hair

5 citations , January 1981

Keratin proteins in hair are complex and come from multiple gene families.

research Electrophoretic analysis of human hair keratins

4 citations , December 1995 in “Anthropologischer Anzeiger”

Family members have similar hair protein patterns, which could be useful for genetic studies.

research Generation of a Novel Inducible and Dermal Papilla‐Specific Wif1‐CreER Knock‐In Mouse Line for Hair Follicle Research

May 2025 in “Experimental Dermatology”

A new genetic tool improves the study of hair growth and potential hair disorder treatments.

research Activation of the OVOL1-OVOL2 axis in the hair bulb and in pilomatricoma and pilomatrix carcinoma

September 2016 in “Journal of dermatological science”

The OVOL1-OVOL2 axis is important for hair follicle differentiation and can help diagnose certain hair-related tumors.

research Mrp3, a Mitogen-Regulated Protein/Proliferin Gene Expressed in Wound Healing and in Hair Follicles

19 citations , May 2001 in “Endocrinology”

Mrp3 may aid in wound healing and hair growth.

research Multiple roles for activated LEF/TCF transcription complexes during hair follicle development and differentiation

990 citations , October 1999 in “Development”

Activated LEF/TCF complexes are crucial for hair development and cycling.