72 citations
,
December 2018 in “Journal of Experimental Zoology Part B Molecular and Developmental Evolution” Corneous beta-proteins evolved uniquely in reptiles and birds, forming scales, claws, beaks, and feathers.
2 citations
,
February 2021 in “Journal of comparative pathology” Sheep with chronic Sarcoptes scabiei dermatitis have altered keratin expression in their skin.
114 citations
,
May 2001 in “Development” Overexpression of Hoxc13 in hair cells causes hair loss and skin issues.
135 citations
,
October 1997 in “Journal of biological chemistry/The Journal of biological chemistry” Trichohyalin is modified by enzymes to form strong structures in hair cells.
16 citations
,
June 2015 in “The journal of investigative dermatology/Journal of investigative dermatology” The enzyme DHHC13 is essential for healthy hair and skin, and its deficiency leads to hair loss and skin problems.
15 citations
,
January 2012 in “Journal of Veterinary Science” Different dog breeds have varying skin thickness and protein expression in their skin.
25 citations
,
September 2014 in “SpringerPlus” Sheep have a unique gene, KAP8-2, that humans don't have, which may affect wool properties.
7 citations
,
February 2002 in “Veterinary Dermatology” Intracorneal vacuoles are common in parakeratotic skin diseases in dogs, especially with more parakeratosis.
14 citations
,
November 1963 in “The journal of investigative dermatology/Journal of investigative dermatology” Pathologic tissues have more soluble proteins than normal tissues.
2 citations
,
September 2004 in “Experimental Dermatology” Keratinocyte adhesion problems can cause skin and hair disorders.
11 citations
,
September 1996 in “Journal of applied polymer science” Potassium cyanide treatment changes hair's disulfide bonds, making it more elastic.
A 5 cm hair sample can reveal blood type and keratin type for forensic use.
6 citations
,
February 2013 in “British Journal of Dermatology” Androgens significantly regulate hair keratin K37 expression.
January 2011 in “Anhui nongye kexue” The vector successfully directed specific gene expression in hair follicles.
May 2025 in “Journal of Developmental Biology” Jawless vertebrates have teeth proteins similar to those in mammalian hair and nails.
5 citations
,
May 2021 in “Small ruminant research” The study found specific proteins that could mark different growth stages of cashmere goat hair and may help improve cashmere production.
55 citations
,
December 2014 in “Dermatologica sinica/Zhōnghuá pífūkē yīxué zázhì” Keratinocytes control how melanocytes work.
8 citations
,
April 2009 in “International journal of oncology” Hair follicle cells resist turning into skin cells.
July 2024 in “bioRxiv (Cold Spring Harbor Laboratory)” Hair loss in certain mice is linked to changes in keratin-related genes.
37 citations
,
January 2010 in “Human Molecular Genetics” FTase and GGTase-I are essential for skin keratinocyte health.
1 citations
,
August 2014 in “OhioLink ETD Center (Ohio Library and Information Network)” Alkylated keratin from human hair can help deliver growth factors for bone healing.
2 citations
,
September 1996 in “Journal of Applied Polymer Science” Potassium cyanide changes hair's disulfide bonds to monosulfide, affecting high-sulfur proteins more.
3 citations
,
March 2009 in “Hirosaki University Repository for Academic Resources (Hirosaki University)” Hirosaki hairless rats have sparse, twisted hair due to missing hair keratin genes.
19 citations
,
May 2008 in “Applied spectroscopy” Human hair has different protein structures in its cuticle and cortex.
6 citations
,
October 2022 in “Journal of cell science” Keratin genes change gradually during skin cell development and should be used carefully as biomarkers.
81 citations
,
May 1986 in “Journal of Investigative Dermatology” 8 citations
,
February 1968 in “Australian Journal of Zoology” The southern elephant seal's skin layer helps waterproof the skin by being tightly connected to hair shafts.
24 citations
,
October 2019 in “Genes” A new sheep gene, KRTAP36-1, may help breed sheep with better wool by reducing prickle factor.
2 citations
,
December 2023 in “International journal of molecular sciences” Understanding keratinization is crucial for treating skin conditions like ichthyoses and psoriasis.
8 citations
,
September 2020 in “Genes & Genomics”