research Catamenial-like seizure exacerbation in mice with targeted ablation of extrasynaptic δGABA-a receptors in the brain
Removing certain brain receptors in mice worsens seizure severity and response to treatment during hormone withdrawal.
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30-60 / 1000+ resultsresearch Development of prostate cancer in a patient with primary hypogonadism: intratumoural steroidogenesis in prostate cancer tissues
Prostate cancer can progress even with low testosterone due to internal hormone production in the tumor.
research Coactivator MED1 Ablation in Keratinocytes Results in Hair-Cycling Defects and Epidermal Alterations
Deleting MED1 in skin cells causes hair loss and skin changes.
research Endocrine controls of primary adult human stem cell biology: Thyroid hormones stimulate keratin 15 expression, apoptosis, and differentiation in human hair follicle epithelial stem cells in situ and in vitro
Thyroid hormones affect hair follicle stem cells by promoting differentiation and reducing growth.
research Progressive expression of PPARGC1α is associated with hair miniaturization in androgenetic alopecia
Increased PPARGC1α relates to hair thinning in common baldness.
research An Assessment on Impact of COVID-19 Infection in a Gender Specific Manner
Men have higher COVID-19 mortality rates than women due to biological and lifestyle factors.
research Risk of Abnormal Pregnancy Completing Chemotherapy for Gestational Trophoblastic Tumor
After chemotherapy for a gestational trophoblastic tumor, normal pregnancy rates are possible, but there's a slightly higher risk of the tumor reoccurring in future pregnancies.
research Inhibition of β-catenin signalling in dermal fibroblasts enhances hair follicle regeneration during wound healing
Blocking β-catenin in skin cells improves hair growth during wound healing.
research Impaired Hair Growth and Wound Healing in Mice Lacking Thyroid Hormone Receptors
Thyroid hormone receptors are essential for hair growth and wound healing.
research Sebaceous immunobiology - skin homeostasis, pathophysiology, coordination of innate immunity and inflammatory response and disease associations
Sebaceous glands play a key role in skin health, immunity, and various skin diseases.
research The impact of VDR expression and regulation in vivo
VDR regulation varies by tissue and is crucial for its biological functions.
research Tissue-Selective Regulation of Androgen-Responsive Genes
The same hormone can affect gene expression differently in various tissues, which could lead to new treatments for conditions like hair loss.
research Endocrine effects of long-term calcineurin inhibitor use in solid organ transplant recipients
Long-term use of calcineurin inhibitors in transplant patients can cause hormone issues that can be managed with proper care.
research Androgen Receptor Ligands: Agonists and Antagonists
Different substances that activate or block the androgen receptor can affect male development and treat conditions like prostate cancer.
research American Society for Laser Medicine and Surgery - 2018 Late-Breaking Abstracts
New treatments and technologies in laser medicine show promise for improving skin conditions, fat reduction, cancer treatment, wound healing, and hair restoration.
research Sox2 in the dermal papilla regulates hair follicle pigmentation
Sox2 controls hair color by affecting pigment production in hair follicles.
research Finasteride treatment and neuroactive steroid formation.
Finasteride treatment can decrease certain steroids and increase others, possibly leading to depression symptoms in some cases.
research Newly Developed Targeted Therapies Against the Androgen Receptor in Triple-Negative Breast Cancer: A Review
Targeting androgen receptors shows promise for treating triple-negative breast cancer, but more research is needed.
research The Stem Cell Niche in Regenerative Medicine
Targeting and modifying the stem cell niche can improve regenerative therapies.
research Digital Pseudopad Correction in a Dog Using a CO 2 Laser
CO₂ laser surgery successfully healed a dog's chronic paw condition.
research The Skin Microenvironment: A Dynamic Regulator of Hair Follicle Development, Cycling and Disease
The skin microenvironment significantly affects hair growth and loss, offering potential treatment avenues.
research Redefining hormone resistance in prostate cancer
The conclusion suggests that prostate cancer should be classified by castration status and that new therapies targeting androgen receptor signaling show promise.
research Anticancer effects of metformin on neuroendocrine tumor cells in vitro
Metformin may help treat neuroendocrine tumors.
research Mechanism of androgenic alopecia: Addressing speculations through empirical evidences
Hair loss in men is mainly caused by hormones and genes, and while current treatments can slow it down, they can't fully stop it.
research Chapter 23. Therapeutic Control of Androgen Action
Understanding how androgens work is key for creating new treatments for prostate issues and hair/skin conditions.
research Enhancement of drug permeation across skin through stratum corneum ablation
Removing the outer skin layer increases drug absorption and offers non-invasive treatment options, with some methods allowing for quick skin recovery.
research Testosterone target therapy: focus on immune response, controversies and clinical implications in patients with COVID-19 infection
Testosterone may have a dual role in COVID-19, potentially worsening outcomes in men, and testosterone therapy could help some patients, but more research is needed.
research Prolongation of off-cycle interval by finasteride is not associated with survival improvement in intermittent androgen deprivation therapy in LNCaP tumor model
Finasteride doesn't improve survival in LNCaP tumor model during off-cycle of therapy.
research Rooster feathering, androgenic alopecia, and hormone-dependent tumor growth: What is in common?
Sex hormones affect hair and feather growth and may help manage alopecia and hormone-dependent cancers.
research Androgen Deprivation Therapy in Prostate Cancer: Focusing on Sexual Side Effects
Androgen Deprivation Therapy for prostate cancer often reduces sexual function but intermittent therapy may be more tolerable.