research GABAAreceptor modulation by neurosteroids in models of temporal lobe epilepsies
Neurosteroids change how GABA_A receptors work in the brain, which could be important for treating temporal lobe epilepsy.
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research How Does pH Fit in with Oscillating Polar Growth?
pH, calcium, and reactive oxygen species regulate plant cell growth, with key roles for NADPH oxidases and plasma membrane H+-ATPases.
research Dermatoses of pregnancy
Pregnancy can cause specific skin conditions that need correct diagnosis and treatment to protect both mother and baby.
research Novel agents for the treatment of alopecia
New treatments for hair loss show promise, especially finasteride for men and a stronger minoxidil formula.
research Study of gene expression alteration in male androgenetic alopecia: evidence of predominant molecular signalling pathways
Hair loss involves immune responses, inflammation, and disrupted signaling pathways.
research Erythropoietin promotes hair shaft growth in cultured human hair follicles and modulates hair growth in mice
Erythropoietin helps hair grow and could be a potential treatment for hair loss.
research Safety aspects of androgen treatment with 5α-dihydrotestosterone
DHT is a strong androgen that may pose less risk to the prostate compared to testosterone.
research Premature adrenarche, polycystic ovary syndrome and intrauterine growth retardation: does a relationship exist?
Low birthweight and rapid weight gain after birth may increase the risk of developing polycystic ovary syndrome.
research Microemulsions as Carriers for Therapeutic Molecules
Microemulsions could improve how drugs are delivered and absorbed in the body.
research Three-Dimensional Proteome-Wide Scale Screening for the 5-Alpha Reductase Inhibitor Finasteride: Identification of a Novel Off-Target
Finasteride may affect PNMT, causing side effects.
research Characteristic Localization of Neuronatin in Rat Testis, Hair Follicle, Tongue, and Pancreas
Neuronatin is found in specific cells within rat testis, hair follicles, tongue, and pancreas, suggesting it has various roles in tissue development and function.
research Paternal Finasteride Treatment Can Influence the Testicular Transcriptome Profile of Male Offspring—Preliminary Study
Father's finasteride use may affect son's fertility and testicular function.
research A computationally inferred regulatory heart aging model including post-transcriptional regulations
Researchers created a model to understand heart aging, highlighting key genes and pathways, and suggesting miR-208a as a potential heart attack biomarker.
research The Role of Histone Demethylases in Disease
Histone demethylases play a key role in the development of many diseases and may be targets for treatment.
research Past and Future Strategies for GPCR Deorphanization
Finding functions for unknown GPCRs is hard but key for making new drugs.
research Recent approaches of antibody therapeutics in androgenetic alopecia
Antibody treatments show promise for hair loss but need more research.
research AN OVERVIEW OF MEDICINAL PLANTS USED FOR THE TREATMENT OF HAIR LOSS
Herbal treatments are gaining interest as alternatives for hair loss.
research Prevalence of Type II diabetes mellitus and insulin resistance in parents of women with polycystic ovary syndrome
Parents of women with PCOS have a higher risk of Type II diabetes and insulin resistance, especially fathers.
research Hormonal Therapy for Acne
Hormonal treatments, including birth control and antiandrogens, can effectively treat acne in women.
research Defining hyperandrogenaemia according to the free androgen index in Chinese women: a cross-sectional study
FAI values above 6.4 may suggest high androgen levels and increased metabolic risks in Chinese women of reproductive age.
research High circulating oestrone and low testosterone correlate with adverse clinical outcomes in men with advanced liver disease
Men with advanced liver disease and high oestrone and low testosterone levels have worse health outcomes.
research Male Androgenetic Alopecia and Cardiovascular Risk Factors: A Case-Control Study
Balding men have higher heart disease risk.
research Hirsutism in the Adolescent Female
The conclusion is that young women with excessive hair growth should be quickly tested for hormonal issues and treated to improve their social well-being.
research Update: The Pathogenesis and Treatment of PCOS
New treatments for PCOS focus on managing symptoms and improving fertility.
research Hirsutism
Most women with excessive hair growth have PCOS; treatment varies and focuses on preventing new hair, with electrolysis as the only permanent removal method.
research Persistent Poor Metabolic Profile in Postmenopausal Women With Ovarian Hyperandrogenism After Testosterone Level Normalization
Postmenopausal women with hyperandrogenism didn't have better metabolic health even after their testosterone levels became normal.
research The role of metformin in the management of polycystic ovary syndrome
Metformin helps improve symptoms and reproductive outcomes in people with polycystic ovary syndrome.
research Determination of rat 5α-reductase type 1 isozyme activity and its inhibition by novel steroidal oxazolines
New steroidal compounds moderately block an enzyme related to testosterone conversion, less effectively than finasteride.
research Updates on Hirsutism: A Narrative Review
The review suggests a comprehensive approach to treat hirsutism, focusing on hair removal, medication, and managing emotional effects.
research Disorders of ovulation
Ovulation disorders are a major cause of infertility and menstrual problems in women.