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research Premature termination of hair follicle morphogenesis and accelerated hair follicle cycling in Iasi congenital atrichia (fz^ica) mice points to fuzzy as a key element of hair cycle control

20 citations , July 2005 in “Experimental dermatology”

The fuzzy gene is crucial for controlling hair growth cycles.

research A mutation in the type II hair keratin KRT86 gene in a Han family with monilethrix

3 citations , January 2011 in “生物医学研究杂志：英文版”

A new mutation in the KRT86 gene causes monilethrix in a Han family.

Loss-Of-Function Mutations of an Inhibitory Upstream ORF in the Human Hairless Transcript Cause Marie Unna Hereditary Hypotrichosis

research Loss-of-function mutations of an inhibitory upstream ORF in the human hairless transcript cause Marie Unna hereditary hypotrichosis

181 citations , January 2009 in “Nature Genetics”

Certain mutations in a hair growth-related gene cause a type of genetic hair loss.

research The nude gene and the skin

41 citations , October 2001 in “Experimental Dermatology”

The nude gene is important for skin and hair development.

research Marie Unna hereditary hypotrichosis caused by a novel mutation in the human hairless transcript

14 citations , July 2010 in “Experimental Dermatology”

A new mutation in the HR gene causes hair loss in a specific family.

research Identification of skin-expressed genes possibly associated with wool growth regulation of Aohan fine wool sheep

30 citations , December 2014 in “BMC Genetics”

Certain genes and proteins may influence wool growth in Aohan fine wool sheep.

research Cyclooxygenase-2 overexpression in the skin of transgenic mice results in suppression of tumor development.

113 citations , May 2002 in “PubMed”

Overexpressing COX-2 in mice skin reduces skin tumor development.

research Regulation of stem cell fate by HSPGs: implication in hair follicle cycling

3 citations , December 2022 in “npj Regenerative Medicine”

HSPGs help control stem cell behavior, affecting hair growth and offering a target for hair loss treatments.

Investigation of the Molecular Identity of the Junctional Zone in Human Skin

research 1351 Investigation of the molecular identity of the junctional zone in human

April 2018 in “The journal of investigative dermatology/Journal of investigative dermatology”

GATA6 is important for maintaining and differentiating cells in a key area of human skin.

research Sostdc1 defines the size and number of skin appendage placodes

56 citations , February 2012 in “Developmental biology”

Sostdc1 controls the size and number of hair and mammary gland structures.

research Hair follicle organoids: advances in construction, applications, and translational challenges

May 2026 in “Frontiers in Cell and Developmental Biology”

Hair follicle organoids can help study hair biology and disorders but need improvements for wider use.

research Pax9 is required for filiform papilla development and suppresses skin-specific differentiation of the mammalian tongue epithelium

56 citations , July 2004 in “Mechanisms of Development”

Pax9 is crucial for proper tongue surface development and preventing skin-like changes.

research Pmg-1 and Pmg-2 constitute a novel family of KAP genes differentially expressed during skin and mammary gland development

22 citations , August 1999 in “Mechanisms of Development”

Pmg-1 and Pmg-2 are new genes important for skin and mammary gland development.

research Venus trap in the mouse embryo reveals distinct molecular dynamics underlying specification of first embryonic lineages

25 citations , July 2015 in “EMBO Reports”

Tmem50b and 2610305D13Rik genes play key roles in early mouse embryo development.

research Acromegaloidism with normal growth hormone secretion associated with X-Tetrasomy

13 citations , June 2006 in “Pituitary”

A woman with acromegaloidism and normal growth hormone levels had a rare X-Tetrasomy, suggesting a need to study X-chromosome genes for their role in growth and facial development.

research Generation of Pax1/PAX1-Specific Monoclonal Antibodies

10 citations , October 2016 in “Monoclonal antibodies in immunodiagnosis and immunotherapy”

Researchers created specific antibodies that detect a protein important in development and various conditions, and can be used for research and diagnosis.

research Msx2 Supports Epidermal Competency during Wound-Induced Hair Follicle Neogenesis

19 citations , March 2018 in “Journal of Investigative Dermatology”

The gene Msx2 is crucial for hair follicle regeneration during wound healing.

research Over-, ectopic-expression of FoxN1 at early life adversely influences lymphopoiesis (HEM3P.280)

May 2014 in “The journal of immunology/The Journal of immunology”

Early over-expression of FoxN1 harms immune and skin development.

research Characterization of New Members of the Human Type II Keratin Gene Family and a General Evaluation of the Keratin Gene Domain on Chromosome 12q13.13

92 citations , February 2005 in “Journal of Investigative Dermatology”

research 882 Syndactyly type III and hypotrichosis in oculodentodigital syndrome with GJA1 mutation

April 2017 in “Journal of Investigative Dermatology”

A boy with Oculodentodigital syndrome had a unique GJA1 gene mutation causing his symptoms.

research Author response: Interplay of opposing fate choices stalls oncogenic growth in murine skin epithelium

December 2020

The balance between cell renewal and differentiation controls the growth of cancerous cells in mouse skin.

Chromatin Remodeler Lymphoid-Specific Helicase (Lsh) Is a Critical Determinant Controlling Postnatal Epidermal Growth, Differentiation, and Response to Injury

research 707 Chromatin remodeler Lymphoid-specific helicase (Lsh) is a critical determinant controlling postnatal epidermal growth, differentiation and response to injury

April 2016 in “Journal of Investigative Dermatology”

Lymphoid-specific helicase (Lsh) is crucial for skin growth, change, and healing after injury.

research Odontogenic Keratocysts Arise from Quiescent Epithelial Rests and Are Associated with Deregulated Hedgehog Signaling in Mice and Humans

35 citations , September 2006 in “American Journal Of Pathology”

Odontogenic keratocysts are caused by abnormal Hedgehog signaling and can lead to tooth and bone issues.

research Hairless Up‐Regulates Tgf‐β2 Expression via Down‐Regulation of miR‐31 in the Skin of “Hairpoor” (Hr^Hp) Mice

11 citations , January 2015 in “Journal of cellular physiology”

HR protein causes abnormal hair cycles by increasing Tgf-β2 and reducing miR-31.

research Identification of key modules and hub genes involved in regulating the feather follicle development of Wannan chickens using WGCNA

3 citations , May 2024 in “Poultry Science”

Certain genes are crucial for feather development in Wannan chickens.

research Multiple roles for activated LEF/TCF transcription complexes during hair follicle development and differentiation

990 citations , October 1999 in “Development”

Activated LEF/TCF complexes are crucial for hair development and cycling.

research More than One Gene Involved in Monilethrix: Intracellular but also Extracellular Players

35 citations , May 2006 in “Journal of Investigative Dermatology”

Monilethrix involves multiple genes affecting hair structure, including DSG4 mutations.

research Shh Gene Regulates the Proliferation and Apoptosis of Dermal Papilla Cells to Affect Its Differential Expression in Secondary Hair Follicle Growth Cycle of Cashmere Goats

7 citations , July 2024 in “Animals”

The Shh gene controls cell growth and death in cashmere goat hair follicles, affecting hair growth.

research Hypotrichosis 14: novel variants of the LSS gene in five Chinese families and insights from literature review

July 2025 in “Human Genomics”

New LSS gene variants help understand congenital hypotrichosis 14 better.

research Bone morphogenetic protein-2 (BMP-2) transactivates Dlx3 through Smad1 and Smad4: alternative mode for Dlx3 induction in mouse keratinocytes

79 citations , January 2002 in “Nucleic Acids Research”

BMP-2 activates the Dlx3 gene in mouse skin cells, important for hair and skin development.

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