April 2023 in “Journal of Investigative Dermatology” Skin cells and immune cells change in a skin condition called hidradenitis suppurativa, and a certain treatment can improve these changes.
February 2026 in “Psychiatria” Stress and emotional suppression can cause hair loss, so addressing both mental and physical health is important.
49 citations
,
October 1988 in “The Journal of Clinical Endocrinology & Metabolism” Leuprolide effectively reduces hair growth in hirsute women at higher doses.
17 citations
,
April 1997 in “Archives of dermatology” The document describes a treatment for excessive hair growth in a teenage girl using medication and birth control, but does not report the results.
22 citations
,
August 2021 in “Frontiers in medicine” Immune cells in Hidradenitis suppurativa become more inflammatory and may be important for treatment targets.
1 citations
,
September 2024 in “Journal of Clinical & Translational Endocrinology” PCOS women have more severe metabolic issues and higher androgen levels than hyperandrogenic women without PCOS.
4 citations
,
January 2019 in “Evidence-based Complementary and Alternative Medicine” Yangyin Qingre Huoxue Prescription may help treat atherosclerosis with fewer liver side effects than simvastatin.
April 2019 in “Journal of the Endocrine Society” Sex hormones may be linked to inflammation in Hidradenitis Suppurativa.
Blocking 5α-reductase can reduce sleep deprivation-related behavioral issues in rats.
3 citations
,
November 2017 in “PubMed” Alopecia areata progression is linked to stress and hormone changes, suggesting new treatment targets.
60 citations
,
August 2005 in “Endocrinology” αMSH may help regulate immune responses in hair follicles and its disruption could lead to hair loss.
December 2000 in “Journal of the Royal Society of Medicine” Antiandrogen therapy may help treat hidradenitis suppurativa.
1 citations
,
January 2025 in “International Journal of Dermatology” Dupilumab can both improve and worsen alopecia areata, with higher IgE levels linked to better outcomes.
14 citations
,
June 2013 in “Joint Bone Spine” ACTH may be an effective first-line treatment for acute calcium pyrophosphate crystal arthritis.
75 citations
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March 1999 in “Fertility and sterility” Finasteride, CPA, and flutamide are all equally effective in reducing excessive hair growth in women.
April 2023 in “The journal of investigative dermatology/Journal of investigative dermatology” Blocking a key energy pathway in human hair follicles can trigger stress responses that stop cell growth.
77 citations
,
March 2021 in “Nature” Stress hormone corticosterone blocks a growth factor to slow down hair stem cell activity and hair growth.
22 citations
,
January 1992 in “PubMed” Higher CSF 5-HIAA levels may predict better response to serotonin re-uptake inhibitors in trichotillomania.
15 citations
,
October 2022 in “Allergy” Dupilumab treatment reduces Th2-related markers and helps hair growth in alopecia areata, showing Th2's role in the condition.
July 2016 in “British journal of dermatology/British journal of dermatology, Supplement” Hirsutism treatment should focus more on patient needs and quality of life.
64 citations
,
March 1984 in “Journal of steroid biochemistry/Journal of Steroid Biochemistry” Cyproterone acetate effectively reduced hair growth in hirsute patients by lowering androgen levels and altering androgen metabolism.
1 citations
,
January 2025 in “Frontiers in Immunology” Genetically at-risk healthy people show similar immune issues as those with Pemphigus vulgaris or Alopecia areata.
8 citations
,
July 2020 in “Clinical, cosmetic and investigational dermatology” Excessive sun protection might cause frontal fibrosing alopecia by disrupting skin immune balance.
October 2007 in “한방재활의학과학회지” People with androgenetic alopecia have an imbalance in their autonomic nervous system activity.
August 2015 in “Psychoneuroendocrinology”
42 citations
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July 2015 in “Journal of The American Academy of Dermatology” The conclusion is that oral contraceptives and antiandrogens can treat hirsutism and acne in women with cutaneous hyperandrogenism, but more research is needed for effective treatments, especially for hair loss.
4 citations
,
January 2022 in “Australasian Journal of Dermatology” Higher HDAC1 levels in alopecia areata suggest HDAC inhibitors might help treat it and acne.
84 citations
,
October 2007 in “The Journal of Immunology” Myeloid-derived suppressor cells help control autoimmune cells and promote hair regrowth in alopecia areata.
14 citations
,
April 2013 in “Journal of dermatological science” Hairless protein reduces Msx2 gene activity, affecting hair follicle development.
November 2025 in “Journal of the European Academy of Dermatology and Venereology” JAK inhibitors may reduce depression in people with alopecia areata.