37 citations
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October 2006 in “Archives of Biochemistry and Biophysics” A unique gene mutation causes vitamin D-resistant rickets without causing hair loss.
36 citations
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October 2000 in “British Journal of Dermatology” A different gene near the hairless gene on chromosome 8p21 causes a rare hair loss condition in a German family.
36 citations
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October 1996 in “Dermatologic Clinics” Mice are useful for researching human hair loss and testing treatments, despite some differences between species.
34 citations
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January 2016 in “Analytical Chemistry” A new method can quickly and accurately detect drugs in hair.
33 citations
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December 2017 in “Journal of neuroendocrinology” Sex and stress steroids quickly change brain cell structures in the hippocampus.
33 citations
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January 2009 in “Contraception” Chlormadinone acetate is a strong, well-tolerated hormone used in birth control and hormone therapy with benefits for menstrual pain and skin conditions.
32 citations
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March 2019 in “Climacteric” Premature ovarian insufficiency (POI) can harm women's sexual health, and they may benefit from hormone therapy and counseling.
32 citations
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April 2000 in “Dermatologic Clinics” Skin diseases, especially psoriasis, greatly affect people's quality of life, similar to chronic diseases.
30 citations
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January 2009 in “Nuclear Receptor Signaling” Hairless protein is crucial for healthy skin and hair, and its malfunction can cause hair loss.
29 citations
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May 1998 in “Bulletin of the American College of Nurse-Midwifery” The document concludes that menopause should be seen as a natural part of aging and managed with personalized care and informed choices.
28 citations
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January 2012 in “Biological & pharmaceutical bulletin” Hairless protein can both repress and activate vitamin D receptor functions, affecting gene regulation.
27 citations
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June 2020 in “Genes” Lykoi cats' unique sparse hair is linked to specific genetic variants in the Hairless gene.
27 citations
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March 2006 in “Journal of cosmetic dermatology” HRT helps improve skin issues caused by menopause.
26 citations
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December 2011 in “Journal of Investigative Dermatology” New gene identification techniques have improved the understanding and classification of inherited hair disorders.
26 citations
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February 2009 in “Drug Development Research” 17α-estradiol is a safe estrogen that might protect the brain and doesn't cause feminization, needing more research for treating brain diseases.
25 citations
,
November 2014 in “Ageing Research Reviews” Skin aging is caused by stem cell damage and can potentially be delayed with treatments like antioxidants and stem cell therapy.
23 citations
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July 2003 in “Journal of Investigative Dermatology” Genetic testing for hairless gene mutations is crucial to correctly diagnose and treat atrichia with papular lesions.
23 citations
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June 2019 in “Bioanalysis” Monitoring steroid hormones in blood can better detect testosterone doping.
22 citations
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October 2018 in “British Journal of Haematology” Women have a higher risk of blood clots from hormonal factors and need careful treatment, especially during pregnancy.
21 citations
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April 2015 in “Psychology Research and Behavior Management” Cognitive-behavioral therapy is the best treatment for hair-pulling disorder, and combining it with other therapies could improve results.
20 citations
,
January 2002 in “Laboratory Animals” Mutations in the hairless gene cause hair loss and skin cysts in rhesus macaques.
19 citations
,
May 2006 in “Clinical and Experimental Dermatology” Researchers found a new mutation causing total hair loss from birth.
18 citations
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October 2009 in “Endocrinology” Different Hairless isoforms affect Vitamin D receptor activity in hair regulation, with one repressing and the other stimulating it.
18 citations
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January 2017 in “Dermatologic Surgery” Combining cosmetic procedures with lifestyle changes improves antiaging results.
18 citations
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July 2016 in “British Journal of Dermatology” Cutaneous lupus erythematosus greatly reduces patients' quality of life.
18 citations
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June 1995 in “International Journal of Dermatology” Women experience various skin issues at different life stages, requiring careful treatment and awareness.
17 citations
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November 2012 in “Journal of Investigative Dermatology” The document concludes that over 500 genes are linked to hair disorders and this knowledge is important for creating new treatments.
17 citations
,
March 2012 in “Journal of biological chemistry/The Journal of biological chemistry” Hairless protein affects hair follicle structure by regulating the Dlx3 gene.
17 citations
,
September 2019 in “Journal of Cell Biology” Hair follicle regeneration may slow tumor growth.
17 citations
,
April 2006 in “Dermatologic Clinics” Older women face various skin issues like dryness and thinning, and treatments are available but can have side effects; proper skin care and legal health decisions are important.