Search

everythinglearnresearchcommunity

for

Search:↓

Scientists successfully created and analyzed the structure of a part of the human androgen receptor with specific modulators and a peptide to understand how it binds differently in various tissues.

A specific genetic mutation may increase male pattern baldness risk, especially in Europeans.

Higher androgen levels and site-specific AR expression cause sex-related skeletal differences, and certain steroids can boost AR expression and androgen effects in bone cells.

Human keratinocytes do not naturally respond to androgens.

The Androgen Receptor could be a target for treating diseases like cancer, but more research is needed to confirm the effectiveness of potential treatments.

Androgen receptor signaling causes early aging of cells important for hair growth by damaging their DNA.

Dexamethasone increases the activity of androgen receptors in human skin cells, which may link it to certain types of hair loss.

Human hair growth is influenced by androgen hormones, and red deer mane follicles have similar hormone receptors.

PGD2 increases androgen receptor activity in hair cells, which could be targeted to treat hair loss.

LH and hCG reduce certain protein levels in women's skin.

RU58841, a substance from France, can potentially block the effects of hormones that cause hair loss and excessive hair growth, performing better than a similar substance, cyproterone acetate.

Dexamethasone increases androgen receptor activity in scalp cells, which might explain stress-related hair loss.

Antisense oligonucleotides can reduce androgen receptor levels in skin cells, suggesting potential for treating skin disorders.

Genetic variation in the androgen receptor gene mainly causes early-onset hair loss, with maternal inheritance playing a key role.

Platelet factor 4 slows down hair growth and could make hair loss treatments more effective if removed.

Beard hair follicles have more androgen receptors than non-balding scalp hair follicles.

5α-reductases increase epitestosterone's effect on androgen receptors.

Finasteride, a hair loss drug, may cause long-term sexual side effects due to changes in hormone receptor levels.

A point mutation in the androgen receptor gene causes complete androgen insensitivity.

Mutations in certain receptors can cause diseases and offer new treatment options.

Estrogen Receptor ß (ERß) is the main hormone controller in human skin and hair follicles, not Estrogen Receptor α (ERα) or the Androgen Receptor (AR).

Interleukin‐1 α reduces androgen receptor levels and increases certain cytokines in human scalp cells.

Hair sensitivity to androgens is partly controlled by specific enzyme expressions in different hair areas.

Silencing SFRP1 alone promotes hair growth, but adding DKK1 does not help.

Chromosomal differences affect how muscle cells respond to testosterone.

Balding hair follicles have reduced growth factors and increased inhibitory factors, suggesting new treatment paths for hair loss.

Scientists have developed a new method to detect steroid abuse in athletes using cell-based tests, which could be the future of anti-doping methods.

Male hormones affect COVID-19 severity and certain drugs targeting these hormones could help reduce the risk.

New compounds with carborane showed anti-androgen effects similar to flutamide.

Researchers created immortal human skin cells with constant testosterone receptor activity to study hair loss and test treatments.