146 citations
,
January 2004 in “Hormones” Human skin acts like a hormone-producing organ, making and managing various hormones important for skin and hair health.
4 citations
,
January 2019 in “Annals of Dermatology” RE-ORGA, a Korean herb extract, may help prevent hair loss.
1 citations
,
January 2015 in “Elsevier eBooks” Certain pesticides and fungicides can interfere with male hormone functions, potentially causing reproductive issues in male rats.
March 2023 in “Natural product sciences” Celtis choseniana may help treat hair loss by reducing androgen effects and boosting hair growth signals.
58 citations
,
January 2003 in “Thrombosis and Haemostasis” Testosterone may slow down wound healing and increase inflammation.
35 citations
,
May 2022 in “Baillière's best practice and research in clinical endocrinology and metabolism/Baillière's best practice & research. Clinical endocrinology & metabolism” Androgens like testosterone are important hormones for both men and women, made differently in each sex and affecting the body by regulating genes and quick interactions with cell components.
14 citations
,
November 2014 in “European journal of medicinal chemistry” Researchers found new potential treatments for conditions related to the androgen receptor, like male hormonal contraception, by testing thousands of compounds.
93 citations
,
February 2009 in “Annals of the New York Academy of Sciences” 5α‐reductase isozymes are crucial for prostate development and health, and targeting them can help prevent and treat prostate issues.
November 2025 in “Pharmacological Research” Plant-derived nanoparticles from Polygoni Multiflori Radix promote hair growth better than Minoxidil by affecting androgen pathways.
January 2014 in “theses.fr (ABES)” Androgens regulate Sertoli cells and affect fertility through specific receptors and coregulators.
August 2013 in “Nature Reviews Drug Discovery” New treatments for cancer and skin disorders show promise in disrupting harmful cell interactions and promoting hair growth.
11 citations
,
July 2001 in “APMIS. Acta pathologica, microbiologica et immunologica Scandinavica./APMIS” Estrogens are key for bone growth spurts in both boys and girls and affect growth into adulthood.
July 2005 in “The American Journal of Human Genetics” The AR gene is linked to male-pattern baldness, TNFSF4 to heart disease, SLC19A3 to BBGD, MCT8 to a syndrome, and segmental duplications to genetic variation.
34 citations
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December 1991 in “Annals of the New York Academy of Sciences” Differences in enzyme activity and androgen receptors in hair follicles may explain why hair loss appears differently in men and women.
5 citations
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January 2017 in “Endocrinology” Genetic defects in testosterone production can cause hormonal and developmental disorders, and more research is needed to understand androgen regulation and develop safer treatments.
3 citations
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January 2016 in “Elsevier eBooks” Steroid hormones are crucial for body functions and have various medical uses, but their misuse can lead to dependence.
1 citations
,
January 2021 in “Research Square (Research Square)” Enzalutamide, a prostate cancer drug, may help prevent COVID-19 by blocking the virus from entering lung cells.
1 citations
,
May 2017 in “InTech eBooks” Hair loss in Androgenetic alopecia (AGA) is due to altered cell sensitivity to hormones, not increased hormone levels. Hair growth periods shorten over time, causing hair to become thinner and shorter. This is linked to miscommunication between cell pathways in hair follicles. There's also a change in gene expression related to blood vessels and cell growth in balding hair follicles. The exact molecular causes of AGA are still unclear.
January 2025 in “International Journal of Molecular Sciences” Fenugreek extract may help treat benign prostatic hyperplasia.
3 citations
,
April 2010 in “Endocrinology” The mouse model suggests male pattern baldness may be due to an enzyme increasing DHT and higher androgen receptor levels in hair follicles.
Alopecia areata, a type of hair loss, may be passed through T cells and has genetic links, while treatments vary in effectiveness. Male pattern baldness can be treated with finasteride and is influenced by androgens in hair follicles.
155 citations
,
October 2002 in “The FASEB Journal” Heart-specific steroid metabolism is crucial in cardiac hypertrophy.
26 citations
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January 2005 in “PubMed” RUM-loaded SLN shows promise for treating acne and hair loss topically.
9 citations
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August 2013 in “Archives of Dermatological Research” A gene called BMAL1 plays a role in controlling hair growth.
1 citations
,
May 2012 in “Hair transplant forum international” Hair loss in men may be caused by inflammation triggered by hormones, and treatments reducing inflammation could potentially promote hair growth.
November 2022 in “Scientific Data” The research identified genes and non-coding RNAs in cells that could be affected by testosterone, which may help understand hair loss and prostate cancer.
August 2019 in “KMOU Repository (Korea Maritime and Ocean University)” Sapium rotundifolium extract may help treat enlarged prostate.
August 1994 in “Journal of dermatological science” Different substances affect hair and skin cell growth in various ways.
49 citations
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January 1994 in “The Journal of Steroid Biochemistry and Molecular Biology” RU 58841 may treat acne, hair loss, and excessive hair growth.
5 citations
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January 2004 in “Japanese journal of geriatrics” Male hormones can cause hair loss, but treatments like Minoxidil and Finasteride can help, and targeting TGF-B1 could be a future solution.