research From structural resilience to cell specification — Intermediate filaments as regulators of cell fate
Intermediate filaments are crucial for cell differentiation and stem cell function.
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research Epigallocatechin Gallate-Mediated Alteration of the MicroRNA Expression Profile in 5α-Dihydrotestosterone-Treated Human Dermal Papilla Cells
Green tea component EGCG may help prevent hair loss by changing microRNA levels in certain scalp cells.
research Serum Ferritin and Vitamin D in Female Hair Loss: Do They Play a Role?
Low iron and vitamin D levels are linked to hair loss in women.
research Regulation of masculinization: androgen signalling for external genitalia development
Male genital development is driven by androgen signaling and understanding it could help address congenital anomalies.
research The biology and clinical application of systemic glucocorticoids
Glucocorticoids are powerful anti-inflammatory drugs that must be used carefully to avoid serious side effects.
research Cutaneous Blood Flow.
Laser Doppler velocimetry is a valuable noninvasive tool for skin blood flow research in dermatology.
research Hair follicle immune privilege and its collapse in alopecia areata
Hair follicles are normally protected from the immune system, but when this protection fails, it can cause hair loss in alopecia areata.
research The IL-23/IL-17 Pathway in Inflammatory Skin Diseases: From Bench to Bedside
Targeting the IL-23/IL-17 pathway effectively treats several inflammatory skin diseases.
research Cell-free adipose extract inhibits hypertrophic scar formation through collagen remodeling and antiangiogenesis
High-concentration cell-free adipose extract reduces scar formation and improves scar appearance.
research Topical fulvestrant solution has no effect on male and postmenopausal female androgenetic alopecia: results from two randomized, proof-of-concept studies
Fulvestrant solution doesn't help hair loss in men and postmenopausal women.
research Particulate matter 2.5 damages skin cells by inducing oxidative stress, subcellular organelle dysfunction, and apoptosis
Tiny pollution particles called PM2.5 can harm skin cells by causing stress, damage to cell parts, and cell death.
research Fatty acids and related lipid mediators in the regulation of cutaneous inflammation
Certain fats in the skin help control inflammation and health, and changing these fats through diet or supplements might treat skin inflammation.
research Off-label uses of retinoids in dermatology
Retinoids are effective for various skin conditions and hair loss but have serious side effects, so low doses are recommended.
research Dopamine is a novel, direct inducer of catagen in human scalp hair folliclesin vitro
Dopamine stops hair growth and pigment production in human scalp hair follicles.
research Peroxisome proliferator-activated receptors (PPARs) and PPAR agonists: the ‘future’ in dermatology therapeutics?
PPAR agonists show promise for skin conditions but need more research before being a main treatment.
research Glutamate transporter Slc1a3 mediates inter‐niche stem cell activation during skin growth
The protein SLC1A3 is important for activating skin stem cells and is necessary for normal hair and skin growth in mice.
research Low Intensity Ultrasound as an Antidote to Taxane/Paclitaxel-induced Cytotoxicity
Low intensity ultrasound may reduce side effects of chemotherapy drugs like paclitaxel.
research Depletion of S100A4+ stromal cells results in abnormal nipple development and nursing failure
Lack of certain cells causes abnormal nipple development and nursing failure.
research Efficacy of a cosmetic product mimicking PRP in androgenetic alopecia
research What does acne genetics teach us about disease pathogenesis?
Acne is significantly influenced by genetics, and understanding its genetic basis could lead to better, targeted treatments.
research The dihydrotestosterone (DHT) hypothesis of prostate cancer and its therapeutic implications
The document suggests that targeting the hormone DHT could be a more effective treatment for prostate cancer than targeting testosterone.
research A review on phytochemical, ethnomedical and pharmacological studies on genus Sophora, Fabaceae
The genus Sophora has compounds with potential health benefits and could lead to new drugs, but more research is needed to understand their effects and safety.
research Long-Term Administration of Triterpenoids From Ganoderma lucidum Mitigates Age-Associated Brain Physiological Decline via Regulating Sphingolipid Metabolism and Enhancing Autophagy in Mice
Taking triterpenoids from Ganoderma lucidum over a long time can help slow down brain aging and improve overall health in mice.
research 411 The efficacy of 1550-nm erbium-glass fractional laser treatment and its effect on the expression of insulin-like growth factor 1 and Wnt/β-catenin in androgenetic alopecia
Finasteride helps female-pattern hair loss.
research Comparison between single- versus double-spin prepared platelet-rich plasma injection in treatment of female pattern hair loss: clinical effect and relation to vascular endothelial growth factor
Both methods improve hair density and thickness; double-spin may be more effective.
research An Update on Drug-Induced Pigmentation
Some drugs can cause skin and hair color changes, often reversible when the drug is stopped.
research Cicatricial Alopecia
The document concludes that treatments for cicatricial alopecia are not well-supported by evidence, but hair transplantation shows more predictable and satisfactory results.
research Tumour Necrosis Factor Alpha, Interferon Gamma and Substance P Are Novel Modulators of Extrapituitary Prolactin Expression in Human Skin
TNFα, IFNγ, and Substance P significantly affect prolactin levels in human skin, suggesting new treatments for skin and hair conditions.
research Aberrant inflammasome activation as a driving force of human autoimmune skin disease
Faulty inflammasome activation may lead to autoimmune skin diseases and could be a target for new treatments.
research Capture of endothelial cells under flow using immobilized vascular endothelial growth factor
A surface with VEGF can specifically capture endothelial cells from flowing fluids.