research Dynamic expression of the zinc-finger transcription factor Trps1 during hair follicle morphogenesis and cycling
Trps1 plays a key role in hair follicle development and cycling.
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240-270 / 1000+ resultsresearch Pmg-1 and Pmg-2 constitute a novel family of KAP genes differentially expressed during skin and mammary gland development
Pmg-1 and Pmg-2 are new genes important for skin and mammary gland development.
research Editors' Picks
New findings suggest targeting IL-23 could treat psoriasis, skin cells can adapt to new roles, direct conversion of skin cells to blood cells may aid cell therapy, removing certain tumor cells could boost cancer immunotherapy, and melanoma may have many tumorigenic cells, not just cancer stem cells.
research Immunohistochemical Expression of the ${\alpha}$ - and ${\gamma}$ -catenin in the Fetal Skin Development
α- and γ-catenins help develop fetal skin by 23 weeks.
research In This Issue
Phosphatidic acid may promote hair growth like minoxidil.
research Dermal‐Epidermal Cross‐Talk: Differential Interactions With Microvascular Endothelial Cells
Human dermal fibroblasts help microvascular endothelial cells grow, but not vice versa.
research Hair Follicle Biology and Topical Minoxidil: Possible Mechanisms of Action
Minoxidil stimulates hair growth by increasing hair thickness and prolonging growth phase.
research High-throughput screening of 3D co-culture hair follicle mimetic tissue with enhanced ECM for the screening of hair growth promoting compounds
The new 3D system helps test hair growth treatments effectively.
research Morphogenetic Events in Hair Follicle Heterotypic Spheroids
Researchers developed a method to create artificial hair follicles that may help with hair loss treatment and research.
research Concepts and Challenges in Hair Follicle Cloning
Hair follicle cloning is possible but faces many challenges before it can replace traditional hair transplants.
research 27 Preclinical ex vivo and in vivo evidence supporting selective inhibition of tyrosine kinase 2-dependent, IL-12-mediated signaling as a novel pharmacological strategy for alopecia areata management
Blocking TYK2 might be a new way to treat hair loss from alopecia areata.
research Integrin signalling regulates YAP/TAZ to control skin homeostasis
YAP and TAZ are crucial for skin cell growth and repair.
research Trans‐species hair growth induction by human hair follicle dermal papillae
Human hair follicle cells can grow hair when put into mouse skin if they stay in contact with mouse cells.
research Unraveling the Link Between Ectodermal Disorders and Primary Immunodeficiencies
Skin abnormalities can indicate immunodeficiency due to shared origins with the immune system.
research CD44 signaling in skin wound healing and regeneration
CD44 signaling can help heal wounds without scars.
research Tracing the cellular origin of cancer
Understanding where cancer cells come from helps create better prevention and treatment methods.
research Regulation of Keratin 9 in Nonpalmoplantar Keratinocytes by Palmoplantar Fibroblasts Through Epithelial–Mesenchymal Interactions
Nonpalmoplantar skin cells can be made to express keratin 9 by interacting with palmoplantar fibroblasts.
research Compartmentation of Mitochondrial and Oxidative Metabolism in Growing Hair Follicles: A Ring of Fire
Growing hair follicles have high mitochondrial activity and ROS in specific regions, aiding hair formation.
research Hairless is a nuclear receptor corepressor essential for skin function
Hairless protein is crucial for healthy skin and hair, and its malfunction can cause hair loss.
research Innate type 2 immunity controls hair follicle commensalism by Demodex mites
Type 2 immunity helps control mite growth in hair follicles, preventing damage.
research Distinct tooth regeneration systems deploy a conserved battery of genes
Different species use the same genes for tooth regeneration.
research Microscopy‐guided laser ablation for the creation of complex skin models with folliculoid appendages
Researchers used a laser to create advanced skin models with hair-like structures.
research Arabidopsis Oil Body-Expressed Oleosin-rhFGF5 Inhibits Hair Growth in Mouse
A protein made in a plant stopped hair growth in mice.
research Scalable production of controllable dermal papilla spheroids on PVA surfaces and the effects of spheroid size on hair follicle regeneration
Larger spheroids improve hair growth, but size doesn't guarantee thicker hair.
research [Wound-induced hair follicle neogenesis: a new perspective on hair follicles regeneration in adult mammals].
Wound-induced hair follicle creation is a complex process in adult mammals that involves various cells and immune responses, and understanding it better could help improve skin healing strategies.
research 175 Understanding immune privilege in an inducible mouse model of primary cicatrcial alopecia
The study found that a key immune pathway protecting hair follicles is reduced in a mouse model of scarring hair loss.
research Activated Kras Alters Epidermal Homeostasis of Mouse Skin, Resulting in Redundant Skin and Defective Hair Cycling
Activating Kras in mouse skin causes excess skin and hair loss.
research STIM1 R304W in mice causes subgingival hair growth and an increased fraction of trabecular bone
The STIM1 R304W mutation in mice leads to bone changes and teeth hair growth.
research Large-Scale Preparation of Hair Follicle Germs Using a Microfluidic Device
A new method using a microfluidic device can prepare hair follicle germs efficiently for potential use in hair loss treatments.
research The expanding significance of keratin intermediate filaments in normal and diseased epithelia
Keratin proteins are increasingly recognized as important for cell health and are linked to many diseases.