130 citations
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June 2003 in “Journal of Investigative Dermatology Symposium Proceedings” Estrogen Receptor ß (ERß) is the main hormone controller in human skin and hair follicles, not Estrogen Receptor α (ERα) or the Androgen Receptor (AR).
86 citations
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August 2000 in “Pigment cell research” Melanocyte activity in hair follicles is linked to the hair growth cycle, being active in growth phases and inactive in rest phases.
November 2023 in “Journal of Investigative Dermatology” Adipose stem cell-derived exosomes may improve hair count and scalp health, potentially outperforming current treatments like minoxidil.
Hair growth is maintained by specific cell signals.
July 2025 in “Scientific Reports” Serotonin helps hair grow by activating certain cells.
25 citations
,
June 2004 in “Journal of Investigative Dermatology” Macrophage-stimulating protein helps hair grow and can start hair growth phase in mice and human hair samples.
January 2010 in “Seoul National University Open Repository (Seoul National University)” Lack of Vitamin D receptors can cause hair loss.
24 citations
,
March 2001 in “Journal of Endocrinology/Journal of endocrinology” Red deer only have androgen receptors in neck hair cells for mane growth during breeding season.
6 citations
,
February 2014 in “Experimental Dermatology” Hair follicle regeneration is possible but challenging, especially in humans, due to the need for specific cells and a better understanding of how they signal growth.
December 2025 in “Preprints.org” Milk-derived exosomes may help treat hair loss by boosting hair cell growth and signaling.
138 citations
,
June 2012 in “Genes & Development” Sonic hedgehog signaling is crucial for hair growth and maintaining hair follicle identity.
December 2024 in “Regenerative Therapy” Inhibiting SFRP1 may help treat hair loss.
32 citations
,
July 2012 in “Stem Cells Translational Medicine” Vitamin D3 can help improve hair growth by enhancing the function of specific skin cells and could be useful in hair regeneration treatments.
211 citations
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April 2013 in “Development” More dermal papilla cells in hair follicles lead to larger, healthier hair, while fewer cells cause hair thinning and loss.
5 citations
,
September 2020 in “Molecules” Extracts from three Polynesian plants were found to promote hair growth by affecting cell growth and gene expression related to hair.
February 2026 in “Cosmetics” Milk-derived exosomes may help treat hair loss by boosting hair follicle growth.
1 citations
,
July 2025 in “Scientific Reports” CD133+ cells are crucial for hair growth.
July 2024 in “Journal of Investigative Dermatology” JW0061 may be a new treatment for hair loss by promoting hair growth through WNT signaling.
2 citations
,
May 2023 in “Marine Drugs” Marine-derived saccharides may help reduce aging effects on skin and hair by promoting cell growth and collagen production.
March 1998 in “Journal of dermatological science” Protease Nexin-1 is found in human hair growth cells and is affected by male hormones.
2 citations
,
June 2022 in “Molecules” Connarus semidecandrus Jack extract promotes hair growth and thickness, reduces prostate cancer cell growth, and could potentially be used as a treatment for hair loss.
July 2023 in “Belarusian State Pedagogical University repository (Belarusian State Pedagogical University)” Litchi twigs and leaves may help treat hair loss and reduce agricultural waste.
September 2021 in “Han'gug mi'saengmul saengmyeong gong haghoeji/Han-guk misaengmul saengmyeong gonghak hoeji” Tetrathelmis tetrathele extract may help prevent hair loss and improve scalp health.
5 citations
,
October 2022 in “Cosmetics” Cell-based models help test if cosmetic ingredients really work for hair growth and skin health.
GPC1 is important for blood vessel growth in hair follicles and could help treat hair loss.
GPC1 is important for hair growth by helping blood vessels form around hair follicles.
GPC1 is important for blood vessel growth in hair follicles and could help treat hair loss.
Glypican-1 is important for hair follicle blood vessel growth and could be a target for treating hair loss.
8 citations
,
April 2020 in “Journal of Ethnopharmacology” Herbs might help with hair loss, but more research is needed to confirm their safety and effectiveness.
April 2026 in “Frontiers in Cell and Developmental Biology” Exosomes from stem cells can rejuvenate the scalp and improve hair growth.