17 citations
,
May 2011 in “Gene Therapy” Using polyethylenimine-DNA to deliver the hTERT gene can stimulate hair growth and may be useful in treating hair loss, but there could be potential cancer risks.
12 citations
,
January 1981 in “Springer eBooks” Environmental factors like temperature and nutrition affect hair growth, with humans showing seasonal hair growth differences.
January 2025 in “Biochemical Pharmacology” Peficitinib can turn human fibroblasts into cells that help grow hair.
April 2023 in “Journal of Investigative Dermatology” Ashwagandha nanoparticles help increase hair growth.
15 citations
,
March 2022 in “Acta Biomaterialia” The new 3D bioprinting method successfully regenerated hair follicles and shows promise for treating hair loss.
January 2020 in “Journal of St. Marianna University” Human placenta extract may promote hair growth by affecting certain lipid compounds.
April 2017 in “The journal of investigative dermatology/Journal of investigative dermatology” Researchers developed a method to grow human hair follicles using 3D-printed skin models and modified cells.
4 citations
,
September 2004 in “Experimental Dermatology” Connexin mutations can cause various diseases like hearing loss and skin disorders.
321 citations
,
December 2009 in “Journal of Dermatological Science” Dermal cells are key in controlling hair growth and could potentially be used in hair loss treatments, but more research is needed to improve hair regeneration methods.
102 citations
,
February 2008 in “The FASEB Journal” One minoxidil-sensitive potassium channel exists in human hair follicles.
51 citations
,
May 2019 in “Biomaterials” Researchers developed a method to grow hair follicles using special beads that could help with hair loss treatment.
18 citations
,
February 2018 in “International Journal of Molecular Sciences” PGD2 increases androgen receptor activity in hair cells, which could be targeted to treat hair loss.
10 citations
,
December 2021 in “Frontiers in cell and developmental biology” Glypican-1 is important for blood vessel growth in hair follicles and could help treat hair loss.
9 citations
,
June 2020 in “Tissue Engineering and Regenerative Medicine” HHORSC exosomes and PL improve hair growth treatment outcomes.
8 citations
,
October 2021 in “Experimental cell research” Engineered vesicles from macrophages help hair growth in mice and humans.
8 citations
,
September 2021 in “EMBO Molecular Medicine” A new small peptide may help hair growth by activating a specific receptor and should be tested in humans.
5 citations
,
March 2023 in “Journal of Cosmetic Dermatology” Plantago asiatica L. extract can promote hair growth by enhancing the anagen phase.
Certain chemicals and drugs can cause hair loss.
115 citations
,
December 2001 in “Endocrinology” Expressing the human vitamin D receptor in skin cells prevents hair loss in certain mice.
21 citations
,
December 2001 in “Endocrinology” Expressing the human vitamin D receptor in skin cells prevents hair loss in certain mice.
9 citations
,
June 2017 in “PubMed” Stem cell therapy could be a promising alternative for hair regrowth with fewer side effects.
5 citations
,
May 2020 in “Pharmaceutical Research” Heat and chemicals improve finasteride delivery to scalp and hair follicles, potentially enhancing treatment for hair loss.
June 2026 in “Journal of Cosmetic Dermatology” Microneedle delivery of a special collagen shows promise for treating hair loss.
January 2026 in “Industrial Crops and Products” Ginsenoside Rf from Panax ginseng promotes hair growth and could be a natural alternative for treating hair loss.
Baldness is often hereditary and linked to male hormones, becoming noticeable when half the hair is lost.
The curly mutation in SELH/Bc mice affects hair and may help study human genetic disorders.
92 citations
,
December 2005 in “The Journal of clinical investigation/The journal of clinical investigation” Human hair follicle stem cells can be isolated using specific markers for potential therapeutic use.
92 citations
,
June 2005 in “Journal of Investigative Dermatology” All-trans retinoic acid causes hair loss by increasing TGF-β2 in hair follicle cells.
37 citations
,
April 2017 in “npj Regenerative Medicine” PDGF signaling is crucial for maintaining and renewing hair follicle stem cells, which could help treat hair loss.
21 citations
,
May 2018 in “Journal of Cosmetic Dermatology” Costunolide helps human hair cells grow and can stimulate hair growth in mice.