434 citations
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October 2003 in “PTR. Phytotherapy research/Phytotherapy research” Natural products in cosmetics are beneficial for skin and hair care with low toxicity.
165 citations
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September 2003 in “Toxicology and applied pharmacology” Blocking COX, especially COX-2, in the skin can reduce inflammation and pain and may help prevent skin cancer.
131 citations
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August 2000 in “International Journal of Dermatology” Inflammation may be linked to hair loss, and targeting specific enzymes could help treat it.
124 citations
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March 2012 in “JAMA” Testosterone's muscle-building effects do not require its conversion to DHT.
61 citations
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May 2010 in “Integrative Cancer Therapies” There is no clear recommendation for using selenium in cancer patients; it may be beneficial to correct low selenium levels before treatment.
54 citations
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July 2002 in “Clinical and Experimental Dermatology” DHT, a testosterone byproduct, causes male pattern baldness.
52 citations
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October 2010 in “Antiviral Therapy” New treatments for Hepatitis C show promise but need more research to confirm their safety and effectiveness for clinical use.
51 citations
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January 2003 in “Hormone Research in Paediatrics” Hormones and their receptors, especially androgens, play a key role in hair growth and disorders like baldness.
50 citations
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April 2000 in “Fertility and Sterility” Diane 35 plus finasteride is more effective in reducing hair growth and androgen levels, but may decrease libido.
45 citations
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April 2018 in “Nature Reviews Urology” Male genital development is driven by androgen signaling and understanding it could help address congenital anomalies.
45 citations
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January 2008 in “Drugs” Dutasteride effectively treats enlarged prostate, reduces prostate cancer risk, and promotes hair regrowth with few side effects.
41 citations
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January 2020 in “Journal of Ovarian Research” Quercetin may help with PCOS symptoms, but more research is needed.
38 citations
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October 1996 in “Dermatologic Clinics” Certain hormone treatments can improve acne and related conditions in women.
37 citations
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January 2015 in “Evidence-based Complementary and Alternative Medicine” An extract from Quercus acutissima bark was found to reduce sebum production and block an enzyme linked to acne.
35 citations
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January 2014 in “Postepy Dermatologii I Alergologii” DHT's role in hair loss is important, but measuring its level for diagnosis is questionable.
32 citations
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March 2020 in “Drug Design Development and Therapy” Finasteride shows promise for female hair loss, but more research needed.
31 citations
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September 2008 in “International Journal of Andrology” 5-alpha-reductase inhibitors may cause a low incidence of erectile dysfunction that decreases over time.
30 citations
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January 2000 in “Dermatologic Clinics” Finasteride and minoxidil are effective FDA-approved treatments for androgenetic alopecia.
27 citations
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January 2017 in “Neuropsychopharmacology” The enzyme 5α-reductase is key in causing psychotic-like effects from sleep deprivation.
24 citations
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January 2013 in “Indian Journal of Dermatology, Venereology and Leprology” Hormonal treatment is effective for women with acne not helped by usual treatments, especially if they have hormonal imbalances.
23 citations
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December 1995 in “Archives of Dermatology” Combination therapy improves hair growth in advanced hair loss.
22 citations
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August 2006 in “Critical Reviews in Plant Sciences” The tropical legume Sesbania rostrata can form nodules in waterlogged conditions using a different method that involves plant hormones and specific genes.
22 citations
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March 2000 in “Clinics in Dermatology” Many treatments for hair loss lack proper testing and FDA approval, so their effectiveness is uncertain.
22 citations
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May 1999 in “International Journal of Dermatology” Hair loss from genetics and hormones can be treated with drugs or surgery.
21 citations
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May 2021 in “Prostate Cancer and Prostatic Diseases” COVID-19 might worsen symptoms and progression of benign prostatic hyperplasia, possibly due to inflammation and metabolic disturbances in the prostate gland. More research is needed to confirm this.
20 citations
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October 2018 in “Clinical Drug Investigation” Dutasteride does not impair mental function in elderly men with enlarged prostate.
20 citations
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August 2018 in “The World Journal of Men's Health” Finasteride may increase erectile dysfunction risk in patients with benign prostatic hyperplasia.
20 citations
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March 2017 in “Reproductive Biology and Endocrinology” Women with PCOS have higher 5α-reductase activity, which may be linked to insulin resistance.
20 citations
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January 2017 in “Nutrition Research and Practice” Corn silk extract helps reduce prostate enlargement symptoms.
14 citations
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April 2021 in “Biology” Thai rice bran extracts, especially from Tubtim Chumphae rice, can significantly reduce the activity of hair loss genes, with x-tocopherol showing potential as an anti-hair loss product.