research Vitamin D and Human Health: Lessons from Vitamin D Receptor Null Mice
Mice without the vitamin D receptor have bone issues and other health problems, suggesting vitamin D is important for preventing various diseases in humans.
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research Hydroxysteroid Dehydrogenase (17β -HSD3, 17β-HSD5, and 3α-HSD3) Inhibitors:Extragonadal Regulation of Intracellular Sex Steroid Hormone Levels
Certain inhibitors can potentially treat prostate cancer and other hormone-dependent conditions by controlling sex hormone levels in cells.
research Localisation and regulation of cholesterol transporters in the human hair follicle: mapping changes across the hair cycle
Cholesterol transport in hair follicles decreases from growth to regression phase.
research Expression of NAD+dependent 15-hydroxyprostaglandin dehydrogenase and protection of prostaglandins in human hair follicle
A substance called compound-1 could help increase hair growth by maintaining prostaglandin levels in hair follicles.
research Candidate SNP markers of reproductive potential are predicted by a significant change in the affinity of TATA-binding protein for human gene promoters
Certain genetic markers linked to reproductive potential were identified by their impact on a protein's ability to bind to genes.
research A missing piece: the spiny mouse and the puzzle of menstruating species
The spiny mouse is a unique menstruating rodent that can help us understand menstruation and reproductive disorders.
research Annotated Patent Selections
The document highlights various patents for new compounds with potential treatments for multiple diseases, including cancer, hormonal disorders, and diabetes.
research Androgens in women
Androgens play a complex role in skin conditions like acne and hair loss in women, and normal blood levels don't always show true androgen status.
research Evidence for Increased 5α-Reductase Activity During Early Childhood in Daughters of Women With Polycystic Ovary Syndrome
Young girls whose mothers have PCOS may have higher activity of a specific enzyme that could lead to developing PCOS later.
research Antioxidant Capacity and Protective Effect of Cow Placenta Extract on D-Galactose-Induced Skin Aging in Mice
Cow placenta extract has strong antioxidant effects and can delay skin aging in mice.
research Protective Effect and Mechanism of Placenta Extract on Liver
Placenta extract may protect and improve liver health by reducing stress, inflammation, and cell death, and promoting regeneration.
research Ovine placental steroid synthesis and metabolism in late gestation†
Diet changes hormone levels in pregnant ewes by affecting metabolism, not placental synthesis.
research Cutaneous hydroxystereoid dehydrogenases and rat-hair-cycle
Certain enzymes react strongly with some hormones in rat skin during hair growth, mainly in sebaceous glands and hair sheaths.
research Androgen biosynthetic pathways in the human prostate
DHT in the human prostate is produced through multiple pathways, not just from testosterone.
research PLACENTA EXTRACT-LOADED NOVASOME SIGNIFICANTLY IMPROVED HAIR GROWTH IN A RAT IN VIVO MODEL
Placenta extract in novasomes improved rat hair growth better than minoxidil and placenta extract in liposomes.
research Human Skin is a Steroidogenic Tissue: Steroidogenic Enzymes and Cofactors Are Expressed in Epidermis, Normal Sebocytes, and an Immortalized Sebocyte Cell Line (SEB-1)
Human skin can produce steroids from cholesterol.
research Placental mRNA Expression of Neurokinin B Is Increased in PCOS Pregnancies with Female Offspring
Pregnant women with PCOS have higher levels of Neurokinin B in the placenta, especially with female babies.
research Determination of 19 Steroid Hormones in Human Serum and Urine Using Liquid Chromatography-Tandem Mass Spectrometry
The method accurately measures 19 steroid hormones in human blood and urine using a small sample and is suitable for large-scale monitoring.
research Delayed Diagnosis of Congenital Adrenal Hyperplasia Due to 3β-Hydroxysteroid Dehydrogenase Type 2 Deficiency
Consider rare forms of CAH for accurate diagnosis and treatment.
research Exploring the impact of ovariectomy on hair growth: can ovariectomized mouse serve as a model for investigating female pattern hair loss in humans?
research The profile of steroid hormones in human fetal and adult ovaries
Fetal ovaries produce different hormones than adult ovaries, and endocrine-disrupting chemicals may affect this process.
research Analytical method for the biomonitoring of bisphenols and parabens by liquid chromatography coupled to tandem mass spectrometry in human hair
A new method accurately detects bisphenols and parabens in human hair.
research AP collagen peptides (APCPs ) promote hair growth by activating the GSK ‐3β/β‐catenin pathway and improve hair condition
AP collagen peptides help hair grow and improve hair health.
research Ingredients of Trichological Shampoos with Alleged Beneficial Effects on Hair—What Is Really Known About Their Efficacy? A Scoping Review of an Area with More Unknowns than Knowns
Most trichological shampoo ingredients lack strong evidence for effectiveness against hair loss.
research Is dehydroepiandrosterone a hormone?
Dehydroepiandrosterone (DHEA) is a prohormone important for producing sex steroids and has potential health benefits.
research Testicular Steroidogenesis
Genetic defects in testosterone production can cause hormonal and developmental disorders, and more research is needed to understand androgen regulation and develop safer treatments.
research Hair care cosmetics
The document explains how shampoos clean, rinses condition, one-step shampoos offer convenience, and hair growth promoters aim to prevent hair loss, emphasizing the importance of scientific evidence for their effectiveness.
research 5α-Reduced glucocorticoids: a story of natural selection
Natural 5α-reduced glucocorticoids might be anti-inflammatory with fewer side effects than current options.
research Basics of androgen synthesis and action
Androgens like testosterone are important hormones for both men and women, made differently in each sex and affecting the body by regulating genes and quick interactions with cell components.
research An Update of Congenital Adrenal Hyperplasia
Congenital Adrenal Hyperplasia is a genetic disorder with two forms, causing symptoms like early puberty and severe acne, but can be identified through screening and treated with glucocorticoids.