39 citations
,
September 2011 in “Tissue Engineering Part B-reviews” Hair follicle regeneration in skin grafts may be possible using stem cells and tissue engineering.
31 citations
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January 2021 in “Experimental Dermatology” Skin organoids are a promising new model for studying human skin development and testing treatments.
September 2025 in “Frontiers in Cell and Developmental Biology” Retinoic acid may help heal skin without scars by reducing fibrosis and supporting skin regeneration.
Elastin-like recombinamers show promise for better wound healing and skin regeneration.
June 2020 in “Journal of Investigative Dermatology” Certain bacteria can enhance skin regeneration.
69 citations
,
June 2017 in “Experimental Biology and Medicine” Advanced human skin models improve drug development and could replace animal testing.
October 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” Immune cells are essential for early hair and skin development and healing.
120 citations
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August 2008 in “The journal of investigative dermatology/Journal of investigative dermatology” Cytokeratin 19 and cytokeratin 15 are key markers for monitoring the quality and self-renewing potential of engineered skin.
46 citations
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May 2012 in “Molecular and Cellular Endocrinology” Human skin produces sex hormones like estrogen and testosterone, influenced by ARO and StAR, which may affect skin elasticity and hair growth.
27 citations
,
August 2006 in “Laboratory Investigation” SCF and ET-1 together significantly increase skin pigmentation and melanin production.
11 citations
,
April 2013 in “SpringerPlus” Human skin's melanocytes respond to light by changing shape, producing pigments and hormones, which may affect sleep patterns.
2 citations
,
September 2022 in “Organoid” A new method was developed to efficiently grow skin hair follicles from stem cells, potentially aiding alopecia treatment.
January 2021 in “Journal of clinical and cosmetic dermatology” Human skin responds to light with protective mechanisms, but more research is needed to understand these processes and their implications for health and therapy.
62 citations
,
February 2016 in “ACS Applied Materials & Interfaces” Technique creates 3D cell spheroids for hair-follicle regeneration.
3 citations
,
February 2009 in “Chinese Journal of Traumatology (english Edition)” Human hair cells can be used to grow new hair on rat ears, suggesting a possible treatment for hair loss.
202 citations
,
August 2007 in “Biomaterials” Artificial skin development has challenges, but new materials and understanding cell behavior could improve tissue repair. Also, certain growth factors and hydrogel technology show promise for advanced skin replacement therapies.
128 citations
,
August 2015 in “Cell Stem Cell” Damage to skin releases dsRNA, which activates TLR3 and helps in skin and hair follicle regeneration.
75 citations
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January 2011 in “Plastic and Reconstructive Surgery” The dermal regeneration template is effective in skin regeneration, reducing scarring, and has potential for future improvements.
36 citations
,
September 2009 in “Journal of Cellular and Molecular Medicine” New treatments targeting skin stem cells show promise for skin repair, anti-aging, and cancer therapy.
31 citations
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July 2017 in “Clinical Science” MicroRNAs are important for skin health and could be targets for new skin disorder treatments.
24 citations
,
January 2019 in “Science China Life Sciences” Chitosan/LiCl composite scaffolds help heal deep skin wounds better.
24 citations
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September 2018 in “Journal of Materials Science: Materials in Medicine” Hyaluronic acid-based HA2 hydrogel helps heal skin wounds better with less scarring.
18 citations
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September 2013 in “Technology” The study introduced a new imaging technology to track skin healing and bone marrow cell activity over time.
14 citations
,
November 2020 in “International Journal of Biological Macromolecules” Mushroom-based scaffolds help heal skin wounds and regrow hair.
4 citations
,
January 2025 in “Frontiers in Pharmacology” Multiomics helps understand and improve skin healing and repair.
1 citations
,
October 2023 in “bioRxiv (Cold Spring Harbor Laboratory)” Printing human stem cells and a special matrix during surgery can help grow new skin and hair-like structures in rats.
January 2026 in “Biomaterials Science” The formulation helps improve wound healing and skin repair.
May 2024 in “Scientific reports” Twist2 is essential for scarless skin healing and hair growth in mouse fetuses.
February 2024 in “Frontiers in physiology” Lymphatic vessels are important for skin repair and could affect skin disease treatments.
Dermal stem cells help regenerate hair follicles and heal skin wounds.