research Diagnostic approach to low‐renin hypertension
Recent genetic insights show that low-renin hypertension includes a range from essential hypertension to secondary or familial forms, affecting diagnosis and treatment.
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research Physiology of the Hypothalamic Pituitary Gonadal Axis in the Male
The document explains how the male reproductive system works, its role in making testosterone, and how conditions like obesity can disrupt it, leading to low testosterone and fertility issues.
research Male hormonal contraception: looking back and moving forward
New male hormonal contraceptives show promise but need more research on long-term effects and funding for larger trials.
research Molecular epidemiology of hypospadias: Review of genetic and environmental risk factors
Both genes and environmental factors like chemicals may contribute to the increase in hypospadias, but the exact causes are still unclear.
research Prostate cancer prevention
Prostate cancer prevention includes diet changes, supplements, and medications, with more answers expected soon.
research Polycystic Ovary Syndrome: A Common Reproductive and Metabolic Disorder Necessitating Early Recognition and Treatment
Early diagnosis and treatment of PCOS is crucial to reduce emotional distress and health risks.
research The Mechanisms and Management of Age-Related Oxidative Stress in Male Hypogonadism Associated with Non-communicable Chronic Disease
Managing oxidative stress might help treat low testosterone and related chronic diseases in aging men.
research 5α-reductase inhibition and hair growth promotion of some Thai plants traditionally used for hair treatment
Some Thai plants, especially Carthamus tinctorius, could help prevent hair loss and promote hair growth without adverse effects.
research Effect of Sparasis crispa Extract on 5α-Reductase Gene in Dermal Papilla Cells
Cauliflower Mushroom extract may help treat male hair loss by affecting hair growth-related genes.
research Updates in the understanding and treatments of skin & hair disorders in women of color
New treatments for skin and hair disorders in women of color address unique biological differences and include specific acne medications, sunscreens, skin lighteners, and hair care adjustments.
research Impact of taxol on dermal papilla cells — A proteomics and bioinformatics analysis
Taxol damages hair growth cells, causing hair loss.
research Efficacy of Oral Supplementation with Serenoa Repens, Pumpkin Seed Extract and Cysteine Combined with Topical Minoxidil 5% Vs Topical Minoxidil 5% Alone in Androgenic Alopecia A Randomised Assessor-Blinded 6-Month, Superiority Trial
Combining supplements with minoxidil improves hair growth more than minoxidil alone.
research ORIGINAL RESEARCH—ENDOCRINOLOGY: Comparison of the Steady‐State Pharmacokinetics, Metabolism, and Variability of a Transdermal Testosterone Patch Versus a Transdermal Testosterone Gel in Hypogonadal Men
The testosterone patch and gel are both effective, but they have different absorption patterns and effects on hormone levels.
research Androgen receptor activation integrates complex transcriptional effects in osteoblasts, involving the growth factors TGF-β and IGF-I, and transcription factor C/EBPδ
DHT affects bone growth by altering gene activity in osteoblasts, potentially complicating steroid use.
research Association between finasteride with subjective memory deficits: a study from the NHANES and FAERS databases
Finasteride use is linked to a higher risk of memory problems.
research Nanotechnological reprogramming of the pathological skin microenvironment in scar formation and atopic dermatitis
Nanotechnology could improve treatment for scars and atopic dermatitis by targeting skin issues more effectively.
research Hormonal regulation in male androgenetic alopecia—Sex hormones and beyond: Evidence from recent genetic studies
Hormones and genes affect hair growth and male baldness.
research Repurposing of approved cardiovascular drugs
Some heart drugs show promise for other conditions, but more research is needed to confirm their effectiveness and safety.
research Genetics and other factors in the aetiology of female pattern hair loss
Female pattern hair loss has unclear causes, possibly involving genetics, hormones, and environment, and needs better treatments.
research Repeated finasteride administration induces depression-like behavior in adult male rats
Finasteride use can cause depression-like behavior in male rats.
research Skin steroidogenesis in health and disease
The skin's ability to produce hormones is linked to various skin conditions, and better understanding this process could lead to new treatments.
research The antiandrogen enzalutamide downregulates TMPRSS2 and reduces cellular entry of SARS-CoV-2 in human lung cells
The drug enzalutamide may reduce the ability of the virus causing COVID-19 to enter lung cells.
research Application of Ethanol Extracts From Alnus sibirica Fisch. ex Turcz in Hair Growth Promotion
Extracts from Alnus sibirica and oregonin may help with hair growth and prevent hair loss.
research Dermatologic Changes in Experimental Model of Long COVID
Mice with a virus similar to COVID-19 had skin damage, but a special treatment helped repair it.
research Alopecia areata
Alopecia areata causes hair loss, has no cure, and various treatments exist.
research Male and Female Androgenetic Alopecia
AGA causes permanent hair loss; women use 2% minoxidil, men use 1 mg finasteride daily.
research The efficacy and use of finasteride in women: a systematic review
Finasteride improves hair growth and reduces hirsutism in women, but side effects and optimal dosages need further research.
research Alternative Medicine for Hair Loss
Some natural remedies may help with hair regrowth, but more research is needed to confirm their effectiveness and safety.
research Do 5α-Reductase Inhibitors Raise Circulating Serum Testosterone Levels? A Comprehensive Review and Meta-Analysis to Explaining Paradoxical Results
5α-Reductase inhibitors do not consistently increase testosterone levels in the blood.
research Crystal Structure of 3-Oxo-4-Aza-5-Alpha-Androstone-17 β-Tert-Butyl Carboxamide with an O···H–(C, N) Acceptor Four-Center Hydrogen Bond
The research shows that hydrogen bonds greatly affect the crystal structure of a Finasteride derivative.