research Enhanced Follicular Delivery of Finasteride to Human Scalp Skin Using Heat and Chemical Penetration Enhancers
Heat and chemicals improve finasteride delivery to scalp and hair follicles, potentially enhancing treatment for hair loss.
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research Effects of Finasteride (MK-906), a 5α-Reductase Inhibitor, on Circulating Androgens in Male Volunteers*
Finasteride safely lowers DHT levels without affecting testosterone.
research Effects of finasteride, a 5 alpha-reductase inhibitor, on circulating androgens and gonadotropin secretion in hirsute women.
Finasteride reduces dihydrotestosterone, increases testosterone, and may treat hirsutism in women.
research Clinical Pharmacokinetics and Pharmacodynamics of Finasteride
Finasteride helps regrow hair and shrink prostate by reducing DHT, with some sexual side effects.
research Effect of Citrullus colocynthis Schard on Testosterone-Induced Benign Prostatic Hyperplasia
Citrullus colocynthis fruit extract and its compound may help treat enlarged prostate.
research Hormonal contraceptives: pharmacology tailored to women's health
New hormonal contraceptives are safer, have fewer side effects, and offer health benefits for women.
research Neuroactive steroid levels and psychiatric and andrological features in post-finasteride patients
Post-finasteride patients show changed neuroactive steroid levels, possibly causing erectile dysfunction and depression.
research New steps forward in the neuroactive steroid field
Neuroactive steroids could become safe, effective treatments with more understanding of their complex brain actions and metabolism.
research The anxiolytic effect of pregnancy in rats is reversed by finasteride
Pregnancy reduces anxiety in rats, but finasteride reverses this effect.
research In This Issue
Advancements in hair biology include new treatments and tools for hair growth and alopecia.
research Treatment guidelines in adult women
Hormonal therapy is effective for treating acne in adult women, especially with signs of high androgen levels.
research Selected Disorders of Skin Appendages—Acne, Alopecia, Hyperhidrosis
The conclusion is that acne, alopecia, and hyperhidrosis are common skin issues with various treatments available, and accurate diagnosis is key for effective management.
research Frontal fibrosing alopecia and lichen planus pigmentosus
Mycophenolic acid may help hair growth, a combination treatment improves hair thickness in male hair loss, and early treatment of frontal fibrosing alopecia is important.
research Health Risks Associated with Long-Term Finasteride and Dutasteride Use: It’s Time to Sound the Alarm
Long-term use of finasteride and dutasteride can cause serious health issues like diabetes and liver problems.
research Identification of 5α-reductase isoenzymes in canine skin
Two types of 5α-reductase are in dog skin, which might make dutasteride better than finasteride for treating dog hair loss.
research Androgens and alopecia
Male hormones, particularly DHT, are linked to male pattern hair loss, and treatments like finasteride can help, but they don't work for postmenopausal women's hair loss, which may have different causes.
research Polycystic ovary syndrome and impact on health
PCOS affects women's health by increasing the risk of diabetes, heart disease, and reproductive issues.
research Inhibition of 5α-reductase alters pregnane metabolism in the late pregnant mare
Inhibiting 5α-reductase increases progesterone levels in late pregnant mares.
research Advances in Knowledge of Androgens: How Intentional and Accidental Neurosteroid Changes Inform Us of Their Action and Role
Finasteride can have lasting negative effects on brain function and behavior by disrupting neurosteroid production.
research Androgens and human hair growth
Androgens can cause hair growth in some areas and hair loss on the scalp.
research Female Pattern Hair Loss
Female pattern hair loss is common, linked to polycystic ovarian syndrome, and treated with topical Minoxidil.
research Anabolic-androgenic steroids and cardiovascular risk
Using steroids can increase the risk of heart problems.
research Treatment strategies for alopecia
Some treatments work for common baldness, but there's less evidence for other hair loss types, and more research is needed.
research Bioactives in Chinese Proprietary Medicine Modulates 5α-Reductase Activity and Gene Expression Associated with Androgenetic Alopecia
Chinese medicine may help treat hair loss by affecting genes and enzyme activity.
research Gender-linked differences in human skin
Male and female skin differ in many ways, which could lead to gender-specific skin treatments.
research Selective induction of apoptosis in the hamster flank sebaceous gland organ by a topical liposome 5-α-reductase inhibitor: A treatment strategy for acne
A topical treatment safely and effectively reduced acne by causing targeted cell death in sebaceous glands without side effects.
research Pharmacology of anabolic steroids
Anabolic steroids can build muscle and strength but have risks and need more research on their clinical benefits and side effects.
research Management of androgenetic alopecia
Treat hair loss with finasteride, minoxidil, or surgery; consider side effects and severity.
research Androgens in women
Androgens play a complex role in skin conditions like acne and hair loss in women, and normal blood levels don't always show true androgen status.
research Neuroactive gonadal drugs for neuroprotection in male and female models of Parkinson's disease
Some hormone-related drugs may protect brain cells in Parkinson's disease differently in men and women.