research Faculty Opinions recommendation of Autosomal-dominant woolly hair resulting from disruption of keratin 74 (KRT74), a potential determinant of human hair texture.
A mutation in the KRT74 gene causes woolly hair by affecting hair texture.
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30-60 / 762 resultsresearch Faculty Opinions recommendation of Autosomal-dominant woolly hair resulting from disruption of keratin 74 (KRT74), a potential determinant of human hair texture.
A mutation in the KRT74 gene causes woolly hair by affecting hair texture.
research A Novel Human Type II Cytokeratin, K6hf, Specifically Expressed in the Companion Layer of the Hair Follicle
K6hf is a unique protein found only in a specific layer of hair follicles.
research Immunohistochemistry of Canine Hair Follicle Stem Cells (cHFSCs) by using CK15 and CK19
Canine hair follicles have stem cells in the bulge region.
research Expression of Keratin 75 (K6hf) in Oral Squamous Cell Carcinoma
Keratin 75 might be important in oral cancer progression.
research Formation of surface membranes in developing mammalian hair fibres
Mature hair surfaces are formed by keratinized cells with developed layers, not just modified plasma membranes.
research Platelet-Rich Plasma in Dermatology: New Insights on the Cellular Mechanism of Skin Repair and Regeneration
PRP helps skin heal, possibly through special cells called telocytes.
research Fetal wound healing using a genetically modified murine model: the contribution of P-selectin
P-selectin is not the only factor that prevents scarring in fetal wound healing in mice.
research Advances in Laser Therapy for Hidradenitis Suppurativa: A Systematic Assessment of Current Evidence
Laser therapy effectively treats all stages of hidradenitis suppurativa, offering a reliable alternative to medication.
research Topographical and developmental studies on target sites of 1,25 (OH2) vitamin D3 in skin
Vitamin D3 affects cell differentiation in specific skin areas.
research Getting to the Core of the Dermal Papilla
The document concludes that understanding dermal papilla cells is key to improving hair regeneration treatments.
research Immunolocalization of junctional proteins in human hairs indicates that the membrane complex stabilizes the inner root sheath while desmosomes contact the companion layer through specific keratins
Junctional proteins stabilize the inner root sheath and connect the companion layer in human hair.
research NG2 Proteoglycan Expression in Mouse Skin: Altered Postnatal Skin Development in the NG2 Null Mouse
NG2 is crucial for normal skin and hair development in mice.
research Localization of Cathepsins B, D, L, LAMP-1 and .MU.-Calpain in Developing Hair Follicles.
Lysosomal proteases and cytoplasmic enzymes help hair follicle cells develop and differentiate.
research Morphogenesis- and Hair Cycle-dependent Expression of Trichohyalin, Peptidylarginine Deiminase Type III and Deiminated Trichohyalin in Rat Dorsal Skin Hair Follicles
THH and PAD type III appear together early in hair growth, but deiminated THH appears later, suggesting another factor is involved.
research Do nanoparticles have a future in dermal drug delivery?
Nanoparticles can improve drug delivery to hair follicles but struggle to penetrate deeper skin layers.
research Hair follicle differentiation and regulation.
Hair follicle growth and development are controlled by specific genes and molecular signals.
research Scaffolds for epithelial and hair follicle regeneration
Electrospun matrices help regenerate skin and hair follicles using PCL and collagen scaffolds.
research In this Issue
New findings on hair keratin, wound healing, and skin blistering were presented.
research Ex vivo detection of SARS CoV 2 spike protein in human hair follicles and potential link to telogen effluvium
COVID-19 may cause hair loss by affecting hair follicles.
research Disturbed Epidermal Structure in Mice with Temporally Controlled Fatp4 Deficiency
Fatp4 is crucial for healthy skin development and function.
research Genetic basis of skin appendage development
Hair, teeth, and mammary glands develop similarly at first but use different genes later.
research Cutaneous Epithelial Stem Cells
Skin and hair renewal is maintained by both fast and slow cycling stem cells, with hair regrowth primarily driven by specific stem cells in the hair follicle bulge. These cells can also help heal wounds and potentially treat hair loss.
research Bulge cells of human hair follicles: segregation, cultivation and properties
Researchers found that bulge cells from human hair can grow quickly in culture and have properties of hair follicle stem cells, which could be useful for skin treatments.
research Epidermal stem cell diversity and quiescence
Epidermal stem cells are diverse and vary in activity, playing key roles in skin maintenance and repair.
research CD4 expression controls epidermal stem cell balance
CD4 is crucial for maintaining skin stem cell balance and aiding wound healing.
research Acidic and basic hair/nail ("hard") keratins: their colocalization in upper cortical and cuticle cells of the human hair follicle and their relationship to "soft" keratins.
Hair and nail cells share similar proteins, indicating a common differentiation pathway.
research Defining Hair Follicles in the Age of Stem Cell Bioengineering
The study found that bioengineered hair follicles work when using cells from the same species but have issues when combining human and mouse cells.
research Characterisation of CD4+ stem cells of the skin and their role in skin homeostasis and tumourigenesis
CD4+ skin cells may be precursors to basal cell carcinoma.
research Human Derived Immortalized Dermal Papilla Cells With a Constant Expression of Testosterone Receptor
Researchers created immortal human skin cells with constant testosterone receptor activity to study hair loss and test treatments.