research Enhanced Differentiation Potential of Pigmented Human Epidermal Equivalents
PmtHEE is a better model for studying pigmented skin because it includes melanocytes and shows improved cell differentiation.
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540-570 / 1000+ results research The hairless (hr) gene is involved in the congential hypotrichosis of Valle del Belice sheep
The hr gene is linked to hair loss in Valle del Belice sheep.
research Engineering Human Skin with Spatially Defined Hair Peg-Like Structures Using Self-Organizing Composite Organoids and Micropatterned Dermal Scaffolds
research Terrestrial vertebrates have two keratin gene clusters; striking differences in teleost fish
Terrestrial vertebrates have balanced keratin gene clusters, unlike teleost fish.
research Hypoxia improves hair inductivity of dermal papilla cells via nuclearNADPH oxidase 4‐mediated reactive oxygen species generation'
Low oxygen levels can make hair-growing cells better at growing hair through a process involving reactive oxygen species.
research Monilethrix: A Novel Mutation (Glu402Lys) in the Helix Termination Motif and the First Causative Mutation (Asn114Asp) in the Helix Initiation Motif of the Type II Hair Keratin hHb6
New mutations in hair keratin genes cause the rare hair disorder monilethrix.
research GPRC6A-Duox1 Axis Regulates the Hair Cycle Through H2O2 Generation
The GPRC6A-Duox1 axis helps control hair growth and loss by affecting hydrogen peroxide production.
research Biomedical Applications of Layer‐by‐Layer Self‐Assembly for Cell Encapsulation: Current Status and Future Perspectives
Layer-by-Layer self-assembly is promising for biomedical uses like tissue engineering and cell therapy, but challenges remain in material safety and process optimization.
research Improvement of Antioxidant Defences in Keratinocytes Grown in Physioxia: Comparison of 2D and 3D Models
Physioxia improves keratinocyte protection against oxidative stress and better mimics real skin conditions.
research Nucleation and growth of macrofibrils in trichocyte (hard-α) keratins
Sheet formation is key to macrofibril structure differences in wool.
research 551 Combining Laser Capture Microdissection and RNAseq Analysis to Generate a Human Anagen Hair Follicle Transcriptome Atlas
Researchers made a detailed map of gene activity for different parts of human hair follicles to help create targeted hair disorder treatments.
research HOXC13 Is Involved in the Regulation of Human Hair Keratin Gene Expression
HOXC13 is crucial for regulating hair keratin genes in hair follicles.
research Novel Application of Layered Expression Scanning for Proteomic Profiling of Plucked Hair Follicles
A new method for studying hair follicles is easier and more precise, useful for hair loss and cancer treatment research.
research Monilethrix: Mutational Hotspot in the Helix Termination Motif of the Human Hair Basic Keratin 6
Monilethrix severity varies and may be influenced by other genetic or environmental factors.
research Two Different Mutations in the Same Codon of a Type II Hair Keratin (hHb6) in Patients with Monilethrix
Mutations in the hHb6 gene cause the hair disorder monilethrix.
research Ultrastructural localization of hair keratins, high sulfur keratin-associated proteins and sulfhydryl oxidase in the human hair
Hair proteins change location and structure as hair cells mature.
research A Unique Type I Keratin Intermediate Filament Gene Family is Abundantly Expressed in the Inner Root Sheaths of Sheep and Human Hair Follicles
research The hairless gene mutated in congenital hair loss disorders encodes a novel nuclear receptor corepressor
The mutated hairless gene causes hair loss by acting as a new type of corepressor affecting thyroid hormone receptors.
research A Contemporary View on Felix Pinkus’ Concept of the Vitreous Membrane
The vitreous membrane in hair follicles changes shape during the hair cycle and may affect hair growth and nutrient exchange.
research Expression of the Intermediate Filament Keratin Gene,K15,in the Basal Cell Layers of Epithelia and the Hair Follicle
K15 gene is mainly active in the basal layers of hair follicles and epithelia, aiding early skin cell development.
research The heart of the hair fiber: How the inner structure of the coat reflects adaptive variation across color, sex, age, and body region in dromedary camels (Camelus dromedarius)
Camel hair structure, not color, helps camels stay cool in the desert.
research Keratin expression in the human hair follicle
research Roles for Msx and Dlx homeoproteins in vertebrate development
Msx and Dlx genes are crucial for development, controlling cell behaviors like growth and differentiation through their roles as gene regulators.
research Exogen involves gradual release of the hair club fibre in the vibrissa follicle model
Hair sheds gradually from the follicle, with readiness to shed indicated by less attachment material.
research SP1 and KROX20 Regulate the Proliferation of Dermal Papilla Cells and Target the CUX1 Gene
SP1 promotes and KROX20 inhibits hair cell growth by affecting the CUX1 gene.
research Faculty Opinions recommendation of Mapping the molecular and structural specialization of the skin basement membrane for inter-tissue interactions.
The skin basement membrane is specialized for different tissue interactions, important for hair growth and attachment.
research BMP-FGF Signaling Axis Mediates Wnt-Induced Epidermal Stratification in Developing Mammalian Skin
Wnt signaling is essential for forming the skin's spinous layer through a BMP-FGF pathway.
research Hair structure anatomy and comparative anatomy1 1Dedicated to the memory of the late Dr. R. E. Rivett whose untimely death prevented his role in co-authorship.
Human hair is complex and grows in cycles starting from embryonic life.
research O02 Ubiquitomics of CYLD-deficient skin tumours reveals dysregulation of hair follicle keratinocyte processes
CYLD deficiency in skin tumors disrupts hair follicle cell processes and protein secretion.
research Catagen in the hairless house mouse
Hairless mice have longer hair follicles and abnormal structures during the catagen phase.