November 2020 in “Research Square (Research Square)” Keratin injections in mice can stimulate hair growth and might help treat hair loss.
Diseased horse foot skin shows increased keratin expression, similar to wound healing in mammals.
135 citations
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October 1997 in “Journal of biological chemistry/The Journal of biological chemistry” Trichohyalin is modified by enzymes to form strong structures in hair cells.
28 citations
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April 1988 in “Archives of Dermatological Research” September 2017 in “Journal of Investigative Dermatology” Activating the hexosamine pathway can improve skin health and increase hair follicle stem cells.
7 citations
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January 2011 in “Biochemistry Research International” Hard α-keratin has a universal molecular structure with a specific superlattice arrangement.
356 citations
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December 1986 in “The journal of cell biology/The Journal of cell biology” Hair and nail cells share similar proteins, indicating a common differentiation pathway.
September 2016 in “Journal of dermatological science” The conclusion is that the variation in hair thinness in patients is mostly due to the amount of underdeveloped hairs, and treatments that thicken fine hairs might work for those with mild to severe conditions.
26 citations
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March 2013 in “Journal of Biomedical Materials Research Part A” Researchers created a 3D hydrogel that mimics human hair follicles, which may help with hair loss treatments.
15 citations
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January 1996 in “Adelaide Research & Scholarship (AR&S) (University of Adelaide)” Keratin gene regulation was emerging, with a key transcription factor found to influence hair growth and gene expression.
7 citations
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January 2017 in “Sub-cellular biochemistry/Subcellular biochemistry” 40 citations
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September 2004 in “Biomacromolecules” The Glu413Lys mutation in keratin affects hair stability, while Glu413Asp does not.
7 citations
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January 2025 in “ACS Applied Materials & Interfaces” The hydrogel made from egg white and zinc speeds up wound healing.
12 citations
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October 1947 in “Journal of the Society of Dyers and Colourists” Mercuric acetate makes wool unshrinkable by changing its elastic properties.
March 2010 in “International Journal of Cosmetic Science” Disulfide bonds affect the melting behavior of hair's crystalline structure, but hair retains some stability even after these bonds are broken.
4 citations
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June 2022 in “Journal of cleaner production” New eco-friendly method strengthens and sets hair using light and causes less damage.
September 2010 in “International Journal of Cosmetic Science” Chemical treatments change hair surface properties, making it more hydrophilic and able to bind conditioners.
May 2009 in “International Journal of Cosmetic Science” Permanent waving damages hair protein and weakens hair, especially with repeated treatments using sodium thioglycolate.
28 citations
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August 1992 in “Differentiation” A new pair of mouse keratins, 65 kD and 48 kD, are found in specific skin areas and are linked to a unique skin differentiation type.
7 citations
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July 2008 in “Experimental Dermatology” The study concluded that a protein important for hair strength is regulated by certain molecular processes and is affected by growth phases.
18 citations
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March 2014 in “Drug Development and Industrial Pharmacy” New gel formulas without ethanol and propylene glycol, containing a minoxidil-methyl-β-cyclodextrin complex, have been created for treating hair loss.
63 citations
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December 1998 in “Biochimica et Biophysica Acta (BBA) - Protein Structure and Molecular Enzymology” The study improved understanding of keratin fiber structure by showing consistent microfibril diameter but varying distances and electron density profiles.
28 citations
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December 2011 in “Biocatalysis and biotransformation” PDI helps restore over-bleached hair's strength and structure by attaching special peptides.
May 2010 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” A mutation in the KRT74 gene causes woolly hair by affecting hair texture.
April 2018 in “Journal of Investigative Dermatology” The keratin network in mouse skin changes during cornification and affects the skin's protective barrier.
April 2025 in “Pharmaceuticals” APA is a promising new compound for repairing damaged hair, outperforming Olaplex® in strength and elasticity.
November 2017 in “Koubunshi rombunshuu/Kōbunshi ronbunshū” Hematin in shampoo helps repair and straighten damaged hair.
August 2024 in “Cosmetics” K18® and Olaplex® both effectively repair bleached hair, improving its strength, smoothness, and overall health.
February 2026 in “Macromolecular Bioscience” Keratin-based hydrogels with calcium are effective for delivering anti-fibrotic drugs.
September 2016 in “Toxicology letters” The 5050 MHA42MCS45 hydrogel blend is suitable for repairing load-bearing soft tissues.