January 2023 in “Skin appendage disorders” Two Hispanic women developed Plica neuropathica, a condition causing tangled hair, possibly due to hair damage and various risk factors.
70 citations
,
February 2007 in “Journal of Investigative Dermatology” K39 and K40 are the last keratins expressed in hair development, completing the hair keratin catalog.
2 citations
,
August 2023 in “Autophagy” Autophagy helps control skin inflammation and cancer responses and regulates hair growth by affecting stem cell activity.
10 citations
,
July 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” Human nails and hair follicles have similar gene activity, especially in the cells that contribute to their growth and development.
8 citations
,
February 1968 in “Australian Journal of Zoology” The southern elephant seal's skin layer helps waterproof the skin by being tightly connected to hair shafts.
January 2002 in “Proceedings of The Japanese Society of Animal Models for Human Diseases” Keratin2-6g is crucial for hair follicle development, with mutations causing cell degeneration and vacuolation.
3 citations
,
June 2022 in “European journal of human genetics” A new type of pachyonychia congenita linked to a specific keratin gene mutation was found in two Pakistani families.
May 2006 in “The Journal of Cell Biology” Keratin 17 is crucial for cell growth in wound healing by aiding protein synthesis.
3 citations
,
May 2012 in “Journal of Biological Macromolecules” Keratin film can effectively mimic human hair for testing hair damage.
2 citations
,
July 2019 in “Indian dermatology online journal” A 17-year-old girl and her brothers have a rare hair condition with long eyelashes, thick eyebrows, and easily pluckable hair.
2 citations
,
February 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” Impaired LEF1 activation speeds up skin cell development in Hutchinson-Gilford Progeria Syndrome.
January 2011 in “The Chinese Journal of Dermatovenereology” The woman's skin condition improved with specific oral and topical treatments.
1 citations
,
June 2006 in “Journal of Cosmetic Dermatology” Photoepilation may disrupt normal wound healing and increase the risk of scars.
April 2017 in “The journal of investigative dermatology/Journal of investigative dermatology” A girl with excessive hair growth had a genetic change on chromosome 17 that reduced the activity of two genes linked to hair growth.
41 citations
,
June 2013 in “PLOS ONE” Engineered skin substitutes can grow hair but have limitations like missing sebaceous glands and hair not breaking through the skin naturally.
Daily hair care may cause holes in hair fibers.
February 2026 in “Journal of Cutaneous and Aesthetic Surgery” Ectopic acanthosis nigricans can occur at surgical sites due to skin graft mismatches.
9 citations
,
November 2024 in “Biotechnology for Sustainable Materials” Keratin-based biomaterials are promising for wound healing, drug delivery, and nerve regeneration due to their biodegradability and biocompatibility.
8 citations
,
June 2009 in “British Journal of Dermatology” Human melanocytes in skin and hair follicles don't express keratin 16 or 6 naturally.
80 citations
,
January 1979 in “Journal of Surgical Oncology” Keratoacanthoma is a common, usually non-dangerous skin tumor that looks like squamous cell carcinoma but rarely becomes severe.
12 citations
,
June 2012 in “Wound Repair and Regeneration” Regulating keratinocyte growth in engineered skin can improve wound healing.
24 citations
,
December 2013 in “Archives of Dermatological Research” January 2019 in “Durham e-Theses (Durham University)” Less stiff collagen promotes higher cell growth in hair follicles.
11 citations
,
January 1997 in “Journal of Dermatological Science” A new protein linked to hair strength was identified, aiding in understanding brittle hair conditions.
2 citations
,
December 2015 in “Journal of dermatology” β-interferon injections for melanoma can cause excessive hair growth at the injection sites.
41 citations
,
December 1988 in “Journal of Investigative Dermatology”
4 citations
,
February 2011 in “Dermatology reports” Acitretin can cause excess tissue growth and hair loss.
28 citations
,
January 2013 in “Stem cells” Certain human skin cells marked by CD44 and ALDH are rich in stem cells capable of long-term skin renewal.
March 2016 in “RepositóriUM (Universidade do Minho)” Molecular dynamics simulations help understand keratin's properties and predict hair's response to treatments.
June 1999 in “Connective tissue”