August 2022 in “IntechOpen eBooks” Congenital Adrenal Hyperplasia is a rare inherited disease causing hormone imbalances, affecting growth, fertility, and heart health, diagnosed through blood tests and treated with medication and lifestyle changes.
January 2026 in “International Journal of Molecular Sciences” Hedgehog pathway inhibitors could be effective in treating melanoma.
The RNA AL136131.3 slows down hair growth and speeds up hair loss by affecting sugar breakdown in hair follicles.
3 citations
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November 2022 in “Frontiers in Oncology” Melanin may help melanoma cells grow by aiding their metabolism.
19 citations
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February 1998 in “Cellular Immunology” Hair growth phase in mice weakens certain immune responses.
7 citations
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February 2021 in “Legal Medicine” Hair analysis showed very high metformin levels in two fatal overdose cases, suggesting it's useful in forensics but sweat may affect results.
July 2023 in “Journal of the ASEAN Federation of Endocrine Societies” Metyrapone effectively stabilizes severe Cushing's disease symptoms before surgery.
1 citations
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January 2015 Hyperandrogenism in women often causes acne and excess hair, treatable with lifestyle changes and medications.
21 citations
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January 2015 in “The Journal of Steroid Biochemistry and Molecular Biology” Progesterone byproduct 5αP stimulates mammary tumor growth, but finasteride can suppress it.
49 citations
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March 2017 in “PubMed” Enhancers and super-enhancers are key in controlling specific gene activity and can play a role in cancer development.
14 citations
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February 2022 in “The Journal of clinical investigation/The journal of clinical investigation” Scientists made a mouse model of a serious skin cancer by changing skin cells with a virus and a specific gene, which is similar to the disease in humans.
January 2022 in “Research Square (Research Square)” Serum AMH levels are a strong marker for diagnosing PCOS in Indian women.
4 citations
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April 1986 in “Cancer Letters” GSH-T levels in hair follicles are similar in smokers and non-smokers and don't increase with certain treatments.
77 citations
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April 1968 in “Development” Excess vitamin A can cause hair follicles to change into gland-like structures.
70 citations
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February 2012 in “Human Reproduction” Many young women who donate blood have hormonal disorders like excess male hormones and PCOS.
November 2022 in “Journal of the Endocrine Society” A rare ovarian tumor caused high testosterone and excess hair in a woman, which was resolved after tumor removal.
9 citations
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January 2011 in “American Journal of Dermatopathology” Pilomatrixoma involves abnormal hair keratin production and cell death, causing debris and cysts.
11 citations
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January 2016 in “International Journal of Biological Macromolecules” Enzymatic phosphorylation of hair keratin improves the effectiveness of hair products with cationic ingredients.
12 citations
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September 2018 in “International Journal of Cosmetic Science” Palmitoyl tetrapeptide-20 may help reduce hair greying and increase melanin production.
May 2017 in “Journal of The American Academy of Dermatology” A woman with a skin disorder was found to have hepatitis C, which may be linked, and was safely treated with methotrexate.
Ribonucleotide excision repair is crucial to prevent skin cancer.
October 2020 in “Journal of the American Society of Nephrology” Drospirenone can hide symptoms of certain hormonal disorders, complicating diagnosis.
1 citations
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May 2013 in “Hair transplant forum international” Non-classical 21 hydroxylase deficiency is an underdiagnosed cause of female hair loss and polycystic ovarian syndrome.
17 citations
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July 2013 in “Amino Acids” Increased ODC activity leads to skin tumors by recruiting stem cells, not by toxic byproducts.
31 citations
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February 1997 in “The Journal of Clinical Endocrinology and Metabolism” People who carry the 21-Hydroxylase Deficiency gene are not more likely to have excessive male hormone levels.
November 2023 in “Journal of Pakistan Society of Internal Medicine.” Methotrexate is effective for rheumatoid arthritis but can cause side effects.
The scant hair in snthr-1Bao mice is likely caused by a deletion affecting the Plcd1 gene.
6 citations
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October 2014 in “Endokrynologia Polska” Excessive hair growth is much more common in Chinese women with PCOS than in the general population.
October 2024 in “Journal of the Endocrine Society” Leydig cell tumors can cause high testosterone and symptoms in postmenopausal women, and removing them improves symptoms.
11 citations
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April 2012 in “Journal of Investigative Dermatology” A specific mutation in PA-PLA1α causes abnormal hair growth.