11 citations
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February 2019 in “Research and reports in forensic medical science” DNA phenotyping helps predict physical traits from DNA with varying accuracy and requires careful ethical and legal handling.
3 citations
,
December 2024 in “International Journal of Dermatology” Premature hair graying is caused by genetics, stress, and lifestyle, and affects mental health.
September 2016 in “Journal of Dermatological Science” Polarizing light microscopy can easily and reliably diagnose congenital keratinizing disorders like Netherton syndrome.
89 citations
,
April 2023 in “Forensic Science International Genetics” Forensic DNA Phenotyping can now better predict appearance, ancestry, and age from DNA, but more research is needed for precise police use.
26 citations
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October 1998 in “Experimental Dermatology” A keratin hHb6 mutation causes a hair disorder with varying severity, influenced by other factors.
5 citations
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March 2023 in “Journal of the American Academy of Dermatology” Prurigo pigmentosa mainly affects middle-aged White and Asian women, often linked to a ketogenic diet, and is best treated with oral antibiotics.
December 2022 in “IntechOpen eBooks” Forensic DNA Phenotyping accurately predicts physical traits and is used in investigations, but needs more diverse population data for confirmation.
22 citations
,
January 1985 in “Journal of Human Evolution/Journal of human evolution” Human skin and hair color variation is mainly due to melanin produced by a few genes, with melanin protecting against sun damage.
145 citations
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March 2010 in “Fertility and Sterility” Different types of polycystic ovary syndrome (PCOS) have varying severity, with Type I being the most severe and common.
July 2023 in “Journal of Biomedical Science” Different people show different symptoms for genetic diseases because of how sensitive their bodies are to small changes in important factors.
26 citations
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December 2011 in “Journal of Investigative Dermatology” New gene identification techniques have improved the understanding and classification of inherited hair disorders.
3 citations
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May 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” Skin lesions in Carney Complex are caused by a gene change in some skin cells that leads to increased pigmentation and may lead to tumors.
Retinoids or their analogs could treat skin pigmentation disorders like melasma and vitiligo.
February 2022 in “Authorea (Authorea)” PAON shows skin patterns due to genetic mosaicism.
15 citations
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December 2016 in “Obstetrics & Gynecology” Most skin changes during pregnancy are harmless and moles don't significantly change, but many women experience pigmentation changes due to hormones and sun exposure.
60 citations
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October 2010 in “Molecular Imaging and Biology” Increased skin pigmentation in mice reduces bioluminescent signal accuracy.
93 citations
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October 2006 in “The International Journal of Biochemistry & Cell Biology” Melanocytes are crucial for skin pigmentation and can affect conditions like melanoma, vitiligo, and albinism, as well as hair color and hearing.
3 citations
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March 2023 in “Cell Biology International” Stem cell-enriched fat grafts improve facial hyperpigmentation better than conventional grafts.
7 citations
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August 2008 in “Immunogenetics” A gene mutation in mice causes increased mast cells and disorganized hair follicles in their skin.
25 citations
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September 1995 in “Biochemistry and Cell Biology” High levels of human keratin 16 in mice cause skin lesions and abnormal skin development.
2 citations
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November 1995 in “American Journal of Obstetrics and Gynecology” Taking vitamin B6 corrected a pregnant woman's metabolic disorder, which changed her hair color.
7 citations
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March 1990 in “Pigment Cell Research” Certain chemicals cause hair graying in black mice but not yellow mice.
25 citations
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March 2007 in “The journal of investigative dermatology/Journal of investigative dermatology” A specific gene mutation causes varying hair loss severity in a Pakistani family.
450 citations
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January 2005 in “The journal of investigative dermatology/Journal of investigative dermatology” Hair color is determined by melanin produced and transferred in hair follicles.
5 citations
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September 2016 in “Security science and technology” DNA can predict physical traits like eye and hair color accurately, especially in Europeans, but predicting other traits and in diverse populations needs more research.
August 2025 in “International Journal of Contemporary Pediatrics” HLD10 can include increased body hair and Mongolian spots.
89 citations
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March 1996 in “Proceedings of the National Academy of Sciences” CD18-deficient mice developed psoriasis-like skin disease, useful for studying inflammatory skin disorders.
15 citations
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May 2013 in “American Journal of Medical Genetics - Part A” People with X-linked hypohidrotic ectodermal dysplasia have no sweat ducts and less, thinner hair.
16 citations
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February 2008 in “PubMed” Vitamin B12 deficiency can cause skin darkening and white hair, but it's reversible.
9 citations
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September 2020 in “Journal of cosmetic dermatology” A woman developed vitiligo from repeated eyebrow microblading.