May 2023 in “Pharmaceuticals” Three specific mutations in the LIPH gene can cause hair loss by damaging the protein's structure and function.
38 citations
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March 1997 in “Journal of interferon & cytokine research” IL-1β inhibits human hair follicle growth.
6 citations
,
December 2023 in “Journal of Molecular Cell Biology” Removing Gsdma1/2/3 genes reduces skin cell overgrowth by blocking a specific cell pathway.
1 citations
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January 2018 Sphingosine 1-phosphate and its receptor S1PR3 are key in controlling mechanical pain.
2 citations
,
September 2022 The PER3 rs772027021 SNP may cause mild skin pigmentation changes in a new subtype of dyschromatosis universalis hereditaria.
3 citations
,
January 2022 in “Journal of neuroendocrinology” Sex hormones affect brain cells differently in males and females.
July 2022 in “The journal of investigative dermatology/Journal of investigative dermatology” A patient with a PLEC mutation has epidermolysis bullosa, muscular dystrophy, and myasthenia gravis, which improved with steroid treatment.
12 citations
,
November 2018 in “Archives of Dermatological Research”
October 2020 in “Medicine - Programa De Formación Médica Continuada Acreditado” Female hyperandrogenism is a condition caused by too much male hormones, leading to skin issues and ovulation problems, often due to Polycystic Ovary Syndrome, and is treated based on individual symptoms.
April 2022 in “PANACEA JOURNAL OF MEDICAL SCIENCES” People with both obvious and not-so-obvious underactive thyroid issues often have higher levels of the hormone prolactin.
February 2024 in “bioRxiv (Cold Spring Harbor Laboratory)” Increased energy use in Pik3r1-related insulin resistance isn't due to Ucp1 thermogenesis.
10 citations
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October 2000 in “PubMed” E6/E7 oncogenes in hair follicles cause continuous hair growth by skipping the resting phase.
1 citations
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July 2024 in “British Journal of Dermatology” Inhibiting certain proteins harms hair follicle immunity and increases IL-33, affecting hair health.
December 2012 in “Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature” The conclusion is that the dermal papilla is crucial for hair follicle regrowth, and hair follicles undergo significant structural changes in addition to cell division during regeneration.
24 citations
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March 2017 in “Archives of Gynecology and Obstetrics” The study found that women with hyperandrogenic PCOS have higher levels of AKT1 and AKT2 proteins in their cells, which may lead to cell dysfunction.
September 2024 in “World Journal of Clinical Oncology” Chemotherapy with docetaxel and cisplatin can cause severe low potassium, requiring careful monitoring and treatment.
44 citations
,
February 2009 in “Pain” Progesterone reduces spinal reflex activity by increasing certain GABA(A) receptor subtypes.
248 citations
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December 2011 in “Journal of Neuroscience” Neurosteroids are crucial for stress response, and targeting specific receptors may help treat certain disorders.
During late pregnancy in rats, hormonal changes increased certain GABAA receptors in specific brain cells.
Giant axonal neuropathy changes the structure of keratin in human hair, making it stiffer and stronger.
37 citations
,
January 2008 in “Gynecological Endocrinology” Shorter CAG repeats in a specific gene may increase male hormone activity and symptoms like acne and excess hair in women with PCOS.
138 citations
,
November 2015 in “Journal of Pharmacology and Experimental Therapeutics” Protoporphyrin IX is useful in cancer treatment but can cause health problems if not properly regulated.
April 2018 in “Journal of Investigative Dermatology” Glycogen metabolism is important for energy and processes in human hair follicles, and hair follicles may produce glucose from lactate.
April 2025 in “International Journal of Cosmetic Science” A new hair perming method avoids damage and lasts longer than traditional methods.
121 citations
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June 2009 in “Journal of Cellular Biochemistry” Human hair follicle stem cells can safely and effectively help nerve regeneration.
115 citations
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November 2004 in “Brain Behavior and Immunity” Stress increases nerve fibers and immune cell activity in mouse skin, possibly worsening skin conditions.
December 2022 in “Biochemical and Biophysical Research Communications” HtrA2 activity is crucial for normal hair growth by regulating fat cell development.
January 2024 in “Genetics in Medicine Open” A new IL6ST gene variant may cause a unique form of hyper-IgE syndrome with skin abscesses and high IgE levels.
April 2019 in “Digital Library of Theses and Dissertations (Universidade de São Paulo)” Hair straightening at pH 1.0 improves alignment but weakens hair more than pH 2.0.
1 citations
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March 2018 in “F1000Research” Diabetic neuropathy in mice is linked to poor mitochondria function and lower brain hormone production.