January 2007 in “Revista del Centro Dermatológico Pascua” A 2-year-old boy was diagnosed with a rare genetic condition causing fragile hair, intellectual issues, and short stature.
January 2021 in “International journal of dermatology, venereology and leprosy sciences” Trichoscopy shows black dots, yellow dots, and empty follicles are common in Alopecia Areata, with broken and exclamation mark hair as typical patterns.
13 citations
,
January 2001 in “Pediatric dermatology” A dark-haired Chinese girl had hair that looked banded under certain light but was normal under a microscope.
4 citations
,
March 2013 in “The American Journal of Cosmetic Surgery” Melanin absorbing light is necessary but not enough for effective hair removal by light treatment.
2 citations
,
October 2023 in “Dermatology practical & conceptual” More research is needed to understand hair and scalp disorders in people with skin of color.
October 2025 in “Indian Journal of Paediatric Dermatology” Zinc treatment improved skin and hair issues in a boy with a zinc-related condition.
1 citations
,
April 2016 in “Journal of Investigative Dermatology” Zinc deficiency causes reversible hair loss by disrupting hair growth and stem cell function.
2 citations
,
June 2023 in “Skin Research and Technology” Yellow dots and short vellus hairs are the most common signs of Alopecia Areata (AA), and trichoscopy can help diagnose AA and track treatment progress.
47 citations
,
January 2013 in “Indian Journal of Dermatology, Venereology and Leprology” Premature graying of hair may suggest health issues and currently lacks effective treatments.
5 citations
,
October 2012 in “Veterinary Pathology” A Doberman Pinscher had a rare form of autoimmune disease causing hair loss and other severe symptoms.
2 citations
,
September 2021 Patients with alopecia areata may have lower vitamin D levels than healthy people.
Screening for iron levels in patients with hair loss may help find a genetic iron overload condition early.
2 citations
,
January 2014 in “Indian dermatology online journal” A person was born with both a rare hairless condition and a type of birthmark, which is an uncommon combination.
4 citations
,
January 2016 in “Skin research and technology” Oxidative hair dye changes hair color and structure but doesn't weaken it.
2 citations
,
May 2007 in “Pediatrics in Review” Thorough history and examination are crucial for diagnosing genetic disorders like juvenile polyposis and hypomelanosis of Ito.
November 2024 in “SKIN The Journal of Cutaneous Medicine” Alopecia areata severity and symptoms vary by race and ethnicity.
February 2026 in “Journal of the American Academy of Dermatology” This study retrospectively analyzed 150 patients with ophiasis, a challenging form of alopecia areata, to propose a novel three-subtype classification based on scalp involvement patterns. The study found that ophiasis predominantly affects females, has a prolonged disease duration, and exhibits lower activity and regrowth rates compared to other alopecia areata subtypes. Trichoscopic and histopathologic analyses indicated significant vellus hair involvement, abundant yellow dots, minimal inflammation, and increased telogen follicles, suggesting chronicity. The proposed subtypes—typical ophiasis, ophiasis with patchy AA, and diffuse ophiasis—showed different prognoses, with ophiasis with patchy AA having a more favorable regrowth. This classification system can predict treatment response and guide early intervention and stratified treatment, despite limitations such as sample size and retrospective design.
1 citations
,
August 2023 in “Clinical Cosmetic and Investigational Dermatology” Exclamation mark hairs help distinguish syphilitic alopecia from alopecia areata.
3 citations
,
March 2010 in “Dermatologica Sinica” A Taiwanese patient had hair loss and skin bumps without the usual gene mutation, suggesting other genetic factors might be involved.
4 citations
,
January 2012 in “Springer eBooks” The document concludes that signs of male and female pattern baldness include uneven hair thickness, yellow spots, skin discoloration around hair follicles, more thin and soft hairs, and many hair follicles with just one hair.
January 2020 in “Revista Dermatológica Centro Uraga” Recognizing trichoscopic features is crucial for diagnosing various hair loss conditions.
8 citations
,
January 2011 in “International journal of trichology” Accurate diagnosis of APL is crucial to avoid unnecessary treatments.
13 citations
,
July 2012 in “Pigment Cell & Melanoma Research” A mutation in the Adam10 gene causes freckle-like spots on Hairless mice.
1 citations
,
May 2006 in “Thyroid Research and Practice” Skin can become dry and thick in hypothyroidism.
February 2023 in “Zenodo (CERN European Organization for Nuclear Research)” Trichoscopy is a useful and affordable tool for diagnosing Alopecia areata.
April 2021 in “Authorea (Authorea)” A 20-year-old woman had stable Progressive Hemifacial Atrophy and Vitiligo after treatment, suggesting a possible link between the conditions.
32 citations
,
December 2017 in “Journal of the American Academy of Dermatology” Alopecia areata patients often have low vitamin D levels.
1 citations
,
January 2018 in “Jornal Brasileiro de Patologia e Medicina Laboratorial” Monilethrix causes brittle hair and hair loss, and it runs in families.
January 2019 in “Global Dermatology” Genetic hair shaft abnormalities can be seen with microscopes and often affect scalp hair.
8 citations
,
January 2014 in “Indian Journal of Paediatric Dermatology” Congenital atrichia with papular lesions causes permanent hair loss and skin bumps from birth.