December 2025 in “Zenodo (CERN European Organization for Nuclear Research)” Current drug safety systems fail to detect long-term side effects, needing improvements to protect health and trust.
26 citations
,
March 2006 in “Endocrine, metabolic & immune disorders. Drug targets” This enzyme helps metabolize fatty acids and isoleucine, and could be key in treating neurological diseases and certain cancers.
Nizoral improved menstrual cycles and reduced hair growth in patients with hyperandrogenism.
April 2019 in “Journal of the Endocrine Society” Bilateral ovarian hyperthecosis is a rare but treatable cause of increased facial hair in postmenopausal women.
January 2026 in “Nature Reviews Urology”
4 citations
,
January 2010 in “Acta dermato-venereologica” Low androgen levels can still cause female pattern hair loss.
November 2012 in “Experimental and Clinical Endocrinology & Diabetes” A new genetic mutation causes severe Leydig cell hypoplasia, affecting sexual development.
1 citations
,
January 2016 in “Case Reports in Clinical Medicine” Hair loss in HIV patients should be tested for syphilis as well.
17 citations
,
April 2009 in “Andrologia” A boy's early puberty caused by a testicular tumor returned to normal after surgery.
1 citations
,
February 2009 in “Clinical and Experimental Dermatology” Hormone-replacement therapy improved a woman's skin condition known as lymphomatoid papulosis.
March 2016 in “Journal of the Turkish-German Gynecological Association” The woman likely has a hormonal imbalance causing excessive hair growth.
April 2017 in “Journal of Investigative Dermatology” People with hidradenitis suppurativa who are more resilient tend to have better quality of life and less anxiety and depression.
38 citations
,
November 2005 in “Journal of Investigative Dermatology Symposium Proceedings” March 2024 in “Journal of the American Academy of Dermatology” 8 citations
,
May 2020 in “Arthritis research & therapy” DHT inhibition may increase spinal bone growth in ankylosing spondylitis.
March 2020 in “Journal of Cosmetic Dermatology” Hair loss affects self-esteem; patients seek effective, low side-effect treatments.
1 citations
,
January 2018 in “Journal of Gynecologic Surgery” Removing both ovaries can treat increased testosterone and related symptoms in postmenopausal women with ovarian hyperthecosis.
May 2024 in “The journal of sexual medicine” Finasteride treatment may cause erectile dysfunction, but stopping it reverses these effects.
33 citations
,
April 2015 in “Cochrane library” Some medicines can reduce excessive hair growth in women, but more research is needed to compare treatments and consider side effects.
52 citations
,
January 1995 in “The Journal of Clinical Endocrinology and Metabolism” Finasteride and spironolactone both reduce hirsutism, but finasteride lowers androgen levels more.
47 citations
,
July 2016 in “Current pharmaceutical design” The document concludes that managing hirsutism in PCOS involves long-term treatment guided by severity, using oral contraceptives and possibly antiandrogens, with attention to individual patient needs.
1 citations
,
November 2022 in “Journal of the Academy of Consultation-Liaison Psychiatry” 24 citations
,
November 2007 in “Expert Opinion on Pharmacotherapy” New and future treatments for male hypogonadism include various forms of testosterone therapy and emerging drugs.
1 citations
,
April 2018 in “Revista da Sociedade Portuguesa de Dermatologia e Venereologia” Hidradenitis suppurativa is a chronic skin condition more common in women, linked to genetics and lifestyle factors, and associated with various other health issues.
1 citations
,
August 2019 in “Evidence-Based Practice” Spironolactone and finasteride are equally effective for hirsutism in transgender women.
July 2024 in “Journal of Pediatric Endocrinology and Metabolism” Ovarian hyperthecosis should be considered in young women with severe male-like symptoms and can be managed with hormone treatments.
6 citations
,
November 2015 in “JAMA” Oral contraceptives help mild hirsutism, while flutamide and spironolactone help severe cases.
August 2016 in “Journal of Investigative Dermatology”
192 citations
,
September 2003 in “The Journal of clinical endocrinology and metabolism/Journal of clinical endocrinology & metabolism” Metformin is effective for treating excessive hair growth in women with PCOS and may work better than the standard treatment in some ways.
71 citations
,
June 2006 in “Human Reproduction” Women with PCOS who have low SHBG are more likely to have low good cholesterol and metabolic syndrome.