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The enzyme RDH12 plays a role in vision and retinal disease, with mutations leading to early onset visual loss and blindness, but the exact disease mechanism is unclear and there are no treatments yet.

Notch/RBP-J signaling is crucial for proper placement and timing of melanocyte development in hair follicles.

Mutations in the KRT85 gene cause hair and nail problems.

Low Vitamin D receptor levels in breast cancer are linked to worse outcomes and more bone metastases, and could be a marker for prognosis.

RU58841, a substance from France, can potentially block the effects of hormones that cause hair loss and excessive hair growth, performing better than a similar substance, cyproterone acetate.

17β-estradiol lowers polyamine oxidase levels in breast cancer cells through estrogen receptor 2.

A vitamin D receptor mutation causes rickets and affects immune responses.

Fgfr2b helps maintain healthy skin and prevent cancer.

Prostaglandin E2 helps prevent hair loss from radiotherapy by protecting hair growth cells and aiding self-repair.

Human bone cells mainly produce a type 1 enzyme that may help regulate bone health.

PRC1 influences skin stem cell development by both turning genes on and off, affecting hair growth and skin cell types.

PP2Acα is essential for proper hair and skin development.

RNA aptamers can specifically block FGF5-related cell growth, potentially treating related diseases or hair disorders.

Suppressing ODC activity reduces tumor growth in hair follicles.

Two sisters with rickets and hair loss had a genetic issue with vitamin D processing, and only improved when given phosphorus supplements.

20(S)-Protopanaxadiol-aglycone may help prevent and treat prostate cancer by reducing androgen receptor activity.

BMPR1a-ECD reduces wrinkles much more effectively than retinoic acid.

PRC2 is essential for maintaining intestinal cell balance and aiding regeneration after damage.

A new mutation in the LIPH gene was found to cause a rare hair disorder in a Japanese boy.

FGF signaling is crucial for starting feather development in chicken embryos.

Mutant cells in hair follicles are influenced by their location and interactions with surrounding cells.

rRSPO1 protein boosts hair growth by activating a key signaling pathway.

The SHJH hr mice with a mutated Hr gene show signs of faster skin aging due to poor antioxidative protection.

Targeting LPA could help treat skin disorders.

CXXC5 can both suppress and promote cancer, making it a complex target for treatment.

PDGF-D boosts stem cell growth and movement, enhancing hair regeneration.

YAP and TAZ proteins are necessary for the development of two types of skin cancer.

A new gene mutation causes vitamin D-resistant rickets and hair loss in two siblings.

The research suggests new treatments for skin cancer could target specific cell growth pathways.