February 2026 in “Applied immunohistochemistry & molecular morphology” CD34+ cells decrease in bald areas, while Sox9 stays high, suggesting hair loss in AGA is linked to stem cell issues.
The YH complex, made from certain plant extracts, effectively promotes hair regrowth and could be a potential treatment for hair loss.
March 2023 in “Research Square (Research Square)” Immune changes and specific genes contribute to male hair loss.
August 2016 in “Journal of Investigative Dermatology” Researchers found a new genetic mutation linked to a hair condition in a Japanese boy.
July 2021 in “Archives of Dermatological Research” Alopecia patients have less GPER-1, which might affect hair loss.
September 2022 in “bioRxiv (Cold Spring Harbor Laboratory)” The research provided new insights into the genetic factors contributing to hair loss and skin conditions by analyzing individual cells from the human scalp.
December 2023 in “Journal of the Endocrine Society” Blocking glucocorticoid receptors improves glucose metabolism in a PCOS mouse model.
54 citations
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May 1994 in “Veterinary Pathology” PTHrP is higher in certain dog tumors and may act as a local growth factor.
September 2023 in “World Rabbit Science” The FRZB gene slows hair growth in rabbits.
6 citations
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January 2004 in “DNA Research” A mutation in the Sgkl gene causes defective hair growth in mice.
5 citations
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August 2012 in “Experimental Dermatology” Artemis phosphorylation at Ser516 may help regulate skin and hair structures.
1 citations
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January 2022 in “Journal of Biosciences and Medicines” Understanding how androgens and their receptors work can lead to improved treatments for skin diseases.
January 2009 in “Journal of Clinical Dermatology” CAG repeat numbers in the AR gene likely don't affect hair loss in Korean men.
31 citations
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July 2004 in “Molecular Medicine” Certain defective glucocorticoid receptor mutants move faster inside cell nuclei and work less effectively.
Researchers found genes in sheep that may affect hair growth and wool quality.
4 citations
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April 2016 in “Experimental Dermatology” AGA causes hair loss through follicle miniaturization and hair cycle changes; regrowth depends on anagen initiation in kenogen follicles.
The arrector pili muscle plays a key role in hair loss in androgenetic alopecia.
January 2019 in “DSpace@MIT (Massachusetts Institute of Technology)” Higher PHGDH levels cause unusual melanin buildup in hair follicles.
1 citations
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February 1991 in “Journal of Biological Chemistry”
9 citations
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January 2005 in “Experimental dermatology” Melatonin receptors in hair follicles help regulate hair growth and could treat hair loss.
1 citations
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January 2023 in “Biochemical and biophysical research communications” Keratin 79 is linked to liver damage and may help diagnose liver diseases.
During late pregnancy in rats, hormonal changes increased certain GABAA receptors in specific brain cells.
July 2023 in “Frontiers in Veterinary Science” Melatonin helps hair grow by activating the RORα receptor in goats.
November 2023 in “Journal of animal science/Journal of animal science ... and ASAS reference compendium” SLICK cattle have better heat tolerance due to specific gene expression and pathway differences.
2 citations
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March 2025 in “Journal of Translational Autoimmunity” Targeting the AhR pathway may help treat alopecia areata.
38 citations
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July 1989 in “Archives of dermatological research” Testosterone causes hair loss in AGA mice, which are good for testing baldness treatments, and both minoxidil and cyproterone acetate can prevent this hair loss.
February 2025 in “International Journal of Molecular Sciences” Maternal melatonin improves offspring hair growth by affecting specific proteins and pathways.
Androgenetic alopecia, or hair loss, is caused by genetic factors and hormones, with different mechanisms in men and women, and can be linked to insulin resistance and polycystic ovary syndrome.
19 citations
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August 2019 in “Expert Opinion on Therapeutic Targets” New treatments for hair loss may target specific pathways and generate new hair follicles.
24 citations
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January 2003 in “Journal of Investigative Dermatology” Blocking a specific receptor slows down hair loss in mice.