249 citations
,
April 2002 in “The FASEB journal” Human skin can make serotonin and melatonin.
76 citations
,
April 2013 in “PLoS ONE” Chronic stress can cause hair loss by increasing oxidative stress, but antioxidants may help.
66 citations
,
July 2015 in “Journal of Molecular Biology” The document concludes that for hair and feather growth, it's better to target the environment around stem cells than the cells themselves.
59 citations
,
November 2018 in “Psychoneuroendocrinology” Lower levels of certain brain chemicals are linked to worse PTSD symptoms in men.
21 citations
,
February 2012 in “Journal of the European Academy of Dermatology and Venereology” Late-onset alopecia areata in Taiwanese patients is more common in women, usually starts at age 57, often involves less than 10% hair loss, and may have a minimal link to thyroid issues.
20 citations
,
March 2013 in “Journal of Lipid Research” The research explains how a human enzyme binds and processes its substrate, which could relate to its role in biological functions and hair loss.
2 citations
,
January 2025 in “Pharmaceutical Research” Angelica gigas Nakai root extracts may help with cancer, pain, memory loss, and metabolic issues.
June 2026 in “Reports of Morphology” A nutrient-rich diet improved skin and hair health in stressed rats.
L-PGDS has specific binding sites for its functions and could help in drug delivery system design.
December 2015 in “University of Birmingham Institutional Research Archive (University of Birmingham)” AKR1C3 could be a treatment target for metabolic issues in PCOS.
71 citations
,
January 2014 in “Journal of Proteome Research” Women with PCOS have different levels of certain fats and proteins in their blood, which could help diagnose the condition.
28 citations
,
May 1986 in “Clinics in endocrinology and metabolism” New compounds may soon be tested to treat excessive hair growth in women.
6 citations
,
September 2005 in “Expert Opinion on Pharmacotherapy” Androgen therapy can help with symptoms like low libido in women, but more research is needed to understand its long-term safety and effects on health.
4 citations
,
October 2024 in “Cureus” PCOS may increase the risk of high blood pressure and heart issues.
March 2026 in “Inflammopharmacology” Ursolic acid from Ochrosia elliptica leaves may help manage PCOS symptoms.
September 2025 in “Journal of Phytonanotechnology and Pharmaceutical Sciences” Licorice has health benefits but can also cause side effects, so it should be used carefully.
March 2026 in “Journal of Cancer Survivorship” Exercise may help reduce treatment side effects and improve survival in metastatic colorectal cancer.
8 citations
,
February 2013 in “Central European Journal of Biology” Melanocytes are diverse cells important for pigmentation and skin health, influenced by genetics and environment.
18 citations
,
January 2001 in “Annual Reports in Medicinal Chemistry” Selective Androgen Receptor Modulators (SARMs) are drugs that can control the effects of androgens in different tissues, potentially having fewer side effects and promising for treating various conditions.
1 citations
,
May 2017 in “InTech eBooks” Some natural remedies may help with hair regrowth, but more research is needed to confirm their effectiveness and safety.
11 citations
,
August 2009 in “Expert Opinion on Drug Discovery” We need better ways to test and understand SARMs to make safer and more effective treatments.
129 citations
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January 2019 in “Clinical medicine insights” Obesity worsens PCOS symptoms, and PCOS may lead to more weight gain; managing both requires a holistic approach that includes mental health.
59 citations
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August 1998 in “International Journal of Dermatology” Genetics and hormones cause hair loss; finasteride treats it safely.
12 citations
,
January 1981 in “Springer eBooks” Environmental factors like temperature and nutrition affect hair growth, with humans showing seasonal hair growth differences.
97 citations
,
March 2009 in “Dermato-endocrinology” Hormones significantly affect hair and oil gland function in the skin, and more research is needed on skin-related hormone disorders.
44 citations
,
February 2016 in “Zoology” Hair cortisol levels in primates are useful for stress assessment but vary by age, sex, species, and hair collection methods.
February 2026 in “Psychoneuroendocrinology” Hair cortisol concentration partly reflects HPA axis regulation but doesn't capture all its complexities.
50 citations
,
November 2020 in “Physiology & behavior” People with depression often have higher hair cortisol levels, while those with PTSD tend to have lower levels, but more research is needed to understand this fully.
5 citations
,
September 2021 in “Cureus” Depression in women with Polycystic Ovarian Syndrome (PCOS) is linked to insulin resistance and hyperandrogenism, and managing these can help reduce depression. Lifestyle changes and Cognitive Behavioral Therapy can be effective treatments.
18 citations
,
February 2020 in “Journal of pharmaceutical and biomedical analysis” The method accurately measures hormones and endocannabinoids in mice, showing gut microbiota diversity affects these levels and may influence stress and reproductive systems.